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Astronauts face numerous health challenges during long-duration space missions, including diminished immunity, bone loss and increased risk of radiation-induced carcinogenesis. Changes in the intestinal flora of astronauts may contribute to these problems. Soy-based fermented food products could provide a nutritional strategy to help alleviate these challenges by incorporating beneficial lactic acid bacteria, while reaping the benefits of soy isoflavones. We carried out strain selection for the development of soy ferments, selecting strains of lactic acid bacteria showing the most effective growth and fermentation ability in soy milk (Streptococcus thermophilus ST5, Bifidobacterium longum R0175 and Lactobacillus helveticus R0052). Immunomodulatory bioactivity of selected ferments was assessed using an in vitro challenge system with human intestinal epithelial and macrophage cell lines, and selected ferments show the ability to down-regulate production of the pro-inflammatory cytokine interleukin-8 following challenge with tumour necrosis factor-alpha. The impact of fermentation on vitamin B1 and B6 levels and on isoflavone biotransformation to agluconic forms was also assessed, with strain variation-dependent biotransformation ability detected. Overall this suggests that probiotic bacteria can be successfully utilized to develop soy-based fermented products targeted against health problems associated with long-term space travel.  相似文献   
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The French mobile station for recording geophysical data has been put in operation at Husafell, Iceland (64°5N, 20°8W) between the 10th of July and the 22nd of September, 1977. This place was more or less conjugated with GEOS when this satellite was near its apogee. The equipments installed in the station for recording VLF and ULF phenomena have characteristics (band-pass, sampling rates) which are identical to the similar equipments installed onboard GEOS. Intercomparison between signals recorded at both points are therefore easy. We present here the results which were obtained in the VLF range.In many occasions, VLF emissions (mainly hiss) do present identical variations in amplitude, with a very abrupt (<1 mn) and very large (>20 dB) decrease in amplitude. Because of their simultaneity at both points, such abrupt variations cannot be interpreted in terms of a sudden ionospheric absorption (associated with an enhanced particle precipitation) nor in terms of a sudden crossing of detached plasma regions. In some cases, these abrupt changes in the VLF intensity are associated with the appearance and disappearance of strong ULF emissions, in the Pc-1 frequency range. Some examples of associated onboard measurements of high energy electron fluxes or cold plasma density (when available) are given, which may help understanding these VLF conjugated relationships.  相似文献   
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Requirements are rarely static, and are ever more likely to evolve as the development time of a system stretches out and its service life increases. In this paper, we discuss the evolution of requirements for the US spacesuit, the extravehicular mobility unit (EMU), as a case study to highlight the need for flexibility in system design. We explore one fundamental environmental change, using the Space Shuttle EMU aboard the International Space Station, and the resulting EMU requirement and design changes. The EMU, like other complex systems, faces considerable uncertainty during its service life. Changes in the technical, political, or economic environment cause changes in requirements, which in turn necessitate design modifications or upgrades. We make the case that flexibility is a key attribute that needs to be embedded in the design of long-lived, complex systems to enable them to efficiently meet the inevitability of changing requirements after they have been fielded.  相似文献   
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The Spatio-Temporal Analysis of Field Fluctuations (STAFF) experiment is one of five experiments which together comprise the Wave Experiment Consortium (WEC). STAFF consists of a three-axis search coil magnetometer to measure magnetic fluctuations at frequencies up to 4 kHz, and a spectrum analyser to calculate in near-real time aboard the spacecraft, the complete auto- and cross-spectral matrices using the three magnetic and two electric components of the electromagnetic field. The magnetic waveform at frequencies below either 10 Hz or 180 Hz is also transmitted. The sensitivity of the search coil is adapted to the phenomena theo be studied: the values 3 × 10-3 nT Hz-1/2 and 3 × 10-5 nT Hz-1/2 are achieved respectively at 1 Hz and 100 Hz. The dynamic range of the STAFF instruments is about 96 dB in both waveform and spectral power, so as to allow the study of waves near plasma boundaries. Scientific objectives of the STAFF investigations, particularly those requiring four point measurements, are discussed. Methods by which the wave data will be characterised are described with emphasis on those specific to four-point measurements, including the use of the Field Energy Distribution function.  相似文献   
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The paper deals with the mission analysis and conceptual design of an interplanetary 6U CubeSats system to be implemented in the L1 Earth–Sun Lagrangian Point mission for solar observation and in-situ space weather measurements.  相似文献   
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At the beginning of the GEOS lifetime, some attempts have been made for taking advantage of the passes over Alaska. GEOS was then commanded in a fixed mode and the corresponding telemetry data were recorded at the NASA stations. For two passes over Jim Creek (48°2N–121°9W) where a powerful VLF transmitter (f 0 = 18.6 kHz) is located, GEOS was put in a specific mode in order to study the magnetospheric electromagnetic field in the vicinity of f 0. The results of one pass (June 11, from 0755 UT) are presented here.During this pass, a strong enhancement of all the e.m. components at f 0 has been observed for a specific period of time, when GEOS was very near to the exact conjugacy with NKL. The distance, as measured on the ground, over which the signal was above -6 dB from the maximum is of the order of 800 km. During the corresponding period of time (0740–0750 UT), the satellite altitude varied between 8000 and 6000 km. The magnetospheric region where the signal is strong appears to be structured, as if there were many ducts.Preliminary results concerning the polarization characteristics of the signal are presented. In the absence of precise measurements of these characteristics, the comparison between the electric and magnetic components of the received signal is not easy to interpret. An examination of the onboard computed correlograms (in the frequency range from f 0 -0.6 kHz to f 0 +3.3 kHz) shows that, for this pass, no VLF emissions were triggered by NKL, at the altitude of the satellite.  相似文献   
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Highly efficient low-thrust propulsion is increasingly applied beyond commercial use, also in mainstream and flagship science missions, in combination with gravity assist propulsion. Another recent development is the growth of small spacecraft solutions, not in size but in numbers and individual capabilities.Just over ten years ago, the DLR-ESTEC Gossamer Roadmap to Solar Sailing was set up to guide technology developments towards a propellant-less and highly efficient class of spacecraft for solar system exploration and applications missions: small spacecraft solar sails designed for carefree handling and equipped with carried application modules.Soon, in three dedicated Gossamer Roadmap Science Working Groups it initiated studies of missions uniquely feasible with solar sails such as Displaced L1 (DL1) space weather advance warning and monitoring, Solar Polar Orbiter (SPO) delivery to very high inclination heliocentric orbit, and multiple Near-Earth Asteroid (NEA) rendezvous (MNR). Together, they demonstrate the capability of near-term solar sails to achieve at least in the inner solar system almost any kind of heliocentric orbit within 10 years, from the Earth-co-orbital to the extremely inclined, eccentric and even retrograde. Noted as part of the MNR study, sail-propelled head-on retrograde kinetic impactors (RKI) go to this extreme to achieve the highest possible specific kinetic energy for the deflection of hazardous asteroids.At DLR, the experience gained in the development of deployable membrane structures leading up to the successful ground deployment test of a (20 m)2, i.e., 20 m by 20 m square solar sail at DLR Cologne in 1999 was revitalized and directed towards a 3-step small spacecraft development line from as-soon-as-possible sail deployment demonstration (Gossamer-1) via in-flight evaluation of sail attitude control actuators (Gossamer-2) to an envisaged proving-the-principle flight in the Earth-Moon system (Gossamer-3). First, it turned the concept of solar sail deployment on its head by introducing four separable Boom Sail Deployment Units (BSDU) to be discarded after deployment, enabling lightweight 3-axis stabilized sailcraft. By 2015, this effort culminated in the ground-qualified technology of the DLR Gossamer-1 deployment demonstrator Engineering Qualification Model (EQM). For mission types using separable payloads, such as SPO, MNR and RKI, design concepts can be derived from the BSDU characteristic of DLR Gossamer solar sail technology which share elements with the separation systems of asteroid nanolanders like MASCOT. These nano-spacecraft are an ideal match for solar sails in micro-spacecraft format whose launch configurations are compatible with ESPA and ASAP secondary payload platforms.Like any roadmap, this one contained much more than the planned route from departure to destination and the much shorter distance actually travelled. It is full of lanes, narrow and wide, detours and shortcuts, options and decision branches. Some became the path taken on which we previously reported. More were explored along the originally planned path or as new sidings in search of better options when circumstance changed and the project had to take another turn. But none were dead ends, they just faced the inevitable changes when roadmaps face realities and they were no longer part of the road ahead. To us, they were valuable lessons learned or options up our sleeves. But for future sailors they may be on their road ahead.  相似文献   
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We present a study of wave particle interaction in the vicinity of interplanetary shocks in the ecliptic plane, as observed by the Ulysses spacecraft. We focus here on some events, for which electromagnetic waves are observed, mainly down-stream of the shock. The whistler mode waves are studied by means of the Unified RAdio and Plasma wave experiment (URAP) and the electron distribution functions are obtained from the Ulysses' plasma experiment (SWOOPS). The results are discussed in the light of electron-cyclotron instabilities.  相似文献   
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