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Astronauts face numerous health challenges during long-duration space missions, including diminished immunity, bone loss and increased risk of radiation-induced carcinogenesis. Changes in the intestinal flora of astronauts may contribute to these problems. Soy-based fermented food products could provide a nutritional strategy to help alleviate these challenges by incorporating beneficial lactic acid bacteria, while reaping the benefits of soy isoflavones. We carried out strain selection for the development of soy ferments, selecting strains of lactic acid bacteria showing the most effective growth and fermentation ability in soy milk (Streptococcus thermophilus ST5, Bifidobacterium longum R0175 and Lactobacillus helveticus R0052). Immunomodulatory bioactivity of selected ferments was assessed using an in vitro challenge system with human intestinal epithelial and macrophage cell lines, and selected ferments show the ability to down-regulate production of the pro-inflammatory cytokine interleukin-8 following challenge with tumour necrosis factor-alpha. The impact of fermentation on vitamin B1 and B6 levels and on isoflavone biotransformation to agluconic forms was also assessed, with strain variation-dependent biotransformation ability detected. Overall this suggests that probiotic bacteria can be successfully utilized to develop soy-based fermented products targeted against health problems associated with long-term space travel.  相似文献   
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THE DIGITAL WAVE-PROCESSING EXPERIMENT ON CLUSTER   总被引:1,自引:0,他引:1  
The wide variety of geophysical plasmas that will be investigated by the Cluster mission contain waves with a frequency range from DC to over 100 kHz with both magnetic and electric components. The characteristic duration of these waves extends from a few milliseconds to minutes and a dynamic range of over 90 dB is desired. All of these factors make it essential that the on-board control system for the Wave-Experiment Consortium (WEC) instruments be flexible so as to make effective use of the limited spacecraft resources of power and telemetry-information bandwidth. The Digital Wave Processing Experiment, (DWP), will be flown on Cluster satellites as a component of the WEC. DWP will coordinate WEC measurements as well as perform particle correlations in order to permit the direct study of wave/particle interactions. The DWP instrument employs a novel architecture based on the use of transputers with parallel processing and re-allocatable tasks to provide a high-reliability system. Members of the DWP team are also providing sophisticated electrical ground support equipment, for use during development and testing by the WEC. This is described further in Pedersen et al. (this issue).  相似文献   
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The French mobile station for recording geophysical data has been put in operation at Husafell, Iceland (64°5N, 20°8W) between the 10th of July and the 22nd of September, 1977. This place was more or less conjugated with GEOS when this satellite was near its apogee. The equipments installed in the station for recording VLF and ULF phenomena have characteristics (band-pass, sampling rates) which are identical to the similar equipments installed onboard GEOS. Intercomparison between signals recorded at both points are therefore easy. We present here the results which were obtained in the VLF range.In many occasions, VLF emissions (mainly hiss) do present identical variations in amplitude, with a very abrupt (<1 mn) and very large (>20 dB) decrease in amplitude. Because of their simultaneity at both points, such abrupt variations cannot be interpreted in terms of a sudden ionospheric absorption (associated with an enhanced particle precipitation) nor in terms of a sudden crossing of detached plasma regions. In some cases, these abrupt changes in the VLF intensity are associated with the appearance and disappearance of strong ULF emissions, in the Pc-1 frequency range. Some examples of associated onboard measurements of high energy electron fluxes or cold plasma density (when available) are given, which may help understanding these VLF conjugated relationships.  相似文献   
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Requirements are rarely static, and are ever more likely to evolve as the development time of a system stretches out and its service life increases. In this paper, we discuss the evolution of requirements for the US spacesuit, the extravehicular mobility unit (EMU), as a case study to highlight the need for flexibility in system design. We explore one fundamental environmental change, using the Space Shuttle EMU aboard the International Space Station, and the resulting EMU requirement and design changes. The EMU, like other complex systems, faces considerable uncertainty during its service life. Changes in the technical, political, or economic environment cause changes in requirements, which in turn necessitate design modifications or upgrades. We make the case that flexibility is a key attribute that needs to be embedded in the design of long-lived, complex systems to enable them to efficiently meet the inevitability of changing requirements after they have been fielded.  相似文献   
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We report the discovery of two hot white dwarfs which have the lowest line-of-sight neutral hydrogen column densities yet measured. The stars were found independently by the ROSAT EUV, Montreal-Cambridge-Tololo, and Edinburgh-Cape surveys. Follow-up observations made using the Voyager 2 ultraviolet spectrometer reveal strong continua shortward of the 912Å Lyman limit from which we deduce that the neutral hydrogen column densities are 1.3 × 1017 and 2.0 × 1017 atoms cm−2.  相似文献   
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The paper deals with the mission analysis and conceptual design of an interplanetary 6U CubeSats system to be implemented in the L1 Earth–Sun Lagrangian Point mission for solar observation and in-situ space weather measurements.  相似文献   
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At the beginning of the GEOS lifetime, some attempts have been made for taking advantage of the passes over Alaska. GEOS was then commanded in a fixed mode and the corresponding telemetry data were recorded at the NASA stations. For two passes over Jim Creek (48°2N–121°9W) where a powerful VLF transmitter (f 0 = 18.6 kHz) is located, GEOS was put in a specific mode in order to study the magnetospheric electromagnetic field in the vicinity of f 0. The results of one pass (June 11, from 0755 UT) are presented here.During this pass, a strong enhancement of all the e.m. components at f 0 has been observed for a specific period of time, when GEOS was very near to the exact conjugacy with NKL. The distance, as measured on the ground, over which the signal was above -6 dB from the maximum is of the order of 800 km. During the corresponding period of time (0740–0750 UT), the satellite altitude varied between 8000 and 6000 km. The magnetospheric region where the signal is strong appears to be structured, as if there were many ducts.Preliminary results concerning the polarization characteristics of the signal are presented. In the absence of precise measurements of these characteristics, the comparison between the electric and magnetic components of the received signal is not easy to interpret. An examination of the onboard computed correlograms (in the frequency range from f 0 -0.6 kHz to f 0 +3.3 kHz) shows that, for this pass, no VLF emissions were triggered by NKL, at the altitude of the satellite.  相似文献   
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