海藻糖载入血小板实验中的超声波强度计算

利用超声波的生物医学效应可强化冻干保护剂海藻糖对细胞膜的渗透特性,对于不同的生物材料,超声波的强度、频率等对细胞的影响程度不同。本文拟提供一种超声波在生物样品中传播的强度估算方法。针对超声波强化海藻糖载入血小板的实验,建立了血小板悬液中超声波的传播模型,并分析得到符合实验要求的各计算参数及边界条件,通过COMSOL Multiphysics软件计算,评估了超声波在样品中的强度分布。计算结果为实验中超声波强度的选择及超声探头与样品等的布置提供了有效的理论指导。同时,为超声波在生物样品中的传播提供了一种新的强度估算方法。     

NUMERICAL STUDY ON EFFECT OF OPERATING TABLE PROTECTED BY HORIZONTAL LAMINAR FLOW SCREEN

Transmission of airborne bacteria is the main factor causing surgical site infection （SSI）, which is harm- ful to patients＇ health and even lives. Numerical study is conducted on the effect of the operating table protected by horizontal laminar flow screen. Discrete phase model （DPM） is used. Numerical simulation is carried out to evalu- ate particle trajectories with the Lagrange approach. As a result, the protecting effect of horizontal laminar flow screen is established, and the protecting parameters of the air velocity supplied by the screen and the protecting dis- tance are optimized. The optimized air velocity supplied by the screen should be at 0.4--0.6 m/s. And the protec- ting distance should be less than 1.3 m. This work provides references for the study on the depuration of operating table or room.