Mercury Ion Analyzer (MIA) onboard Mercury Magnetospheric Orbiter: MMO

The Mercury Magnetopsheric Orbiter (MMO) is one of the spacecraft of the BepiColombo mission; the mission is scheduled for launch in 2014 and plans to revisit Mercury with modern instrumentation. MMO is to elucidate the detailed plasma structure and dynamics around Mercury, one of the least-explored planets in our solar system. The Mercury Plasma Particle Experiment (MPPE) on board MMO is a comprehensive instrument package for plasma, high-energy particle, and energetic neutral particle atom measurements. The Mercury Ion Analyzer (MIA) is one of the plasma instruments of MPPE, and measures the three dimensional velocity distribution of low-energy ions (from 5 eV to 30 keV) by using a top-hat electrostatic analyzer for half a spin period (2 s). By combining both the mechanical and electrical sensitivity controls, MIA has a wide dynamic range of count rates for the proton flux expected around Mercury, which ranges from 10⁶ to 10¹² cm⁻² s⁻¹ str⁻¹ keV⁻¹, in the solar wind between 0.3 and 0.47 AU from the sun, and in both the hot and cold plasma sheet of Mercury’s magnetosphere. The geometrical factor of MIA is variable, ranging from 1.0 × 10⁻⁷ cm² str keV/keV for large fluxes of solar wind ions to 4.7 × 10⁻⁴ cm² str keV/keV for small fluxes of magnetospheric ions. The entrance grid used for the mechanical sensitivity control of incident ions also work to significantly reduce the contamination of solar UV radiation, whose intensity is about 10 times larger than that around Earth’s orbit.     

Expression of p53-regulated genes in human cultured lymphoblastoid TSCE5 and WTK1 cell lines after spaceflight in a frozen state

The 53 kDa tumor suppressor protein p53 is generally thought to contribute to the genetic stability of cells and to protect cells from DNA damage through the activity of p53-centered signal transduction pathways. To clarify the effect of space radiation on the expression of p53-dependent regulated genes, gene expression profiles were compared between two human cultured lymphoblastoid cell lines: one line (TSCE5) has a wild-type p53 gene status, and the other line (WTK1) has a mutated p53 gene status. Frozen human lymphoblastoid cells were stored in a freezer in the International Space Station (ISS) for 133 days. Gene expression was analyzed using DNA chips after culturing the space samples for 6 h on the ground after their return from space. Ground control samples were also cultured for 6 h after being stored in a frozen state on the ground for the same time period that the frozen cells were in space. p53-Dependent gene expression was calculated from the ratio of the gene expression values in wild-type p53 cells and in mutated p53 cells. The expression of 50 p53-dependent genes was up-regulated, and the expression of 94 p53-dependent genes was down-regulated after spaceflight. These expression data identified genes which could be useful in advancing studies in basic space radiation biology. The biological meaning of these results is discussed from the aspect of gene functions in the up- and down-regulated genes after exposure to low doses of space radiation.     

In-flight Performance and Initial Results of Plasma Energy Angle and Composition Experiment (PACE) on SELENE (Kaguya)

MAP-PACE (MAgnetic field and Plasma experiment—Plasma energy Angle and Composition Experiment) on SELENE (Kaguya) has completed its ～1.5-year observation of low-energy charged particles around the Moon. MAP-PACE consists of 4 sensors: ESA (Electron Spectrum Analyzer)-S1, ESA-S2, IMA (Ion Mass Analyzer), and IEA (Ion Energy Analyzer). ESA-S1 and S2 measured the distribution function of low-energy electrons in the energy range 6 eV–9 keV and 9 eV–16 keV, respectively. IMA and IEA measured the distribution function of low-energy ions in the energy ranges 7 eV/q–28 keV/q and 7 eV/q–29 keV/q. All the sensors performed quite well as expected from the laboratory experiment carried out before launch. Since each sensor has a hemispherical field of view, two electron sensors and two ion sensors installed on the spacecraft panels opposite each other could cover the full 3-dimensional phase space of low-energy electrons and ions. One of the ion sensors IMA is an energy mass spectrometer. IMA measured mass-specific ion energy spectra that have never before been obtained at a 100 km altitude polar orbit around the Moon. The newly observed data show characteristic ion populations around the Moon. Besides the solar wind, MAP-PACE-IMA found four clearly distinguishable ion populations on the dayside of the Moon: (1) Solar wind protons backscattered at the lunar surface, (2) Solar wind protons reflected by magnetic anomalies on the lunar surface, (3) Reflected/backscattered protons picked-up by the solar wind, and (4) Ions originating from the lunar surface/lunar exosphere.