SPR生物传感器在生命科学及在航天医学中的应用

表面等离子体共振生物传感器在分析生物分子相互作用方面，具有灵敏度高、实时在线、简单快捷和抗干扰能力强等优点，被广泛应用于临床检验、药物筛选等研究领域；因其能满足空间特殊环境下的使用要求，在航天医学领域具有广阔的应用前景．本文综述了表面等离子体共振生物传感器的原理、特点、在生命科学研究中的应用及在航天医学中的应用前景．     

磨削表面粗糙度在线实时测量的研究

在试验研究的基础上,研制了一种新的光纤表面粗糙度在线测量系统。以光散射法为理论基础,用光纤束作为传感器,并用单片机进行数据处理和实时显示。针对外圆磨削在线检测中存在的冷却液、工件尺寸变化、环境干扰以及仪器的装夹与对中等问题进行了研究,找到了改进或解决的办法,从而更利于该测试技术的实施与推广。     

工件表面轮廓均方根斜率的光散射测量

描述并确定具有明显纹理粗糙表面均方根斜率的光散射技术(均方根斜率是联合表面轮廓高度和波长特性的混合参数)。称为散射光锥法(The scattered light-conemethod)的该技术是基于激光角散射检测阵列(DALLAS——Defector Array for Laser LishtAngular Scattering),它用于测量粗糙表面散射光角分布的仪器。均方根斜率是从DALLAS光散射图象的角宽得到的。一般可以发现角宽(即估计的均方根斜率)对光的入射角和散射角变化相当大时是不敏感的。这些结果与表面材料无关,并且对正弦和随机粗糙表面都是有效的。介绍了散射光锥法的测量原理、实验、数据分析和几点结论。     

GH4169材料磨削后数控抛光表面残余应力分析

数控抛光能够达到一致性较高的表面粗糙度要求。试验研究了羊毛毡轮数控抛光层数对磨削后GH4169表面残余应力的影响,进给方向表面残余正应力随深度增加先升高后下降,而垂直进给方向表面残余正应力先基本不变后下降,优化抛光层数为3层。针对磨削后抛光工艺,提出了"加强筋"模型,将羊毛毡轮抛光过程分为两个阶段,解释了抛光对表面残余应力的影响机理,并改变抛光参数进行了初步的试验验证。     

Effects of Mach numbers on Magnus induced surface pressure

Experimental and numerical methods were used to investigate the Magnus phenomena over a spinning projectile. The pressure force acting on the surface of a spinning projectile was measured for various cases by employing a relatively novel experimental technique. A set of miniature pressure sensors along with a data acquisition board, battery and storage memory were placed inside a spinning model and the surface pressure were obtained through a remotely controlled system. Circumferential pressures of the model for both rotational and static conditions were obtained at two different free stream Mach numbers of 0.4 and 0.8 and at different angles of attack. The results showed the ability of this new test method to measure the very small Magnus force via surface pressures over the projectile. The results provide a deep insight into the flow structure and illustrate changes in the cross-flow separation locations as a result of rotation. Similar results were obtained by the numerical simulations and were compared with the experimental data.     

A surface parametric control and global optimization method for axial flow compressor blades

An aerodynamic optimization method for axial flow compressor blades available for engineering is developed in this paper. Bezier surface is adopted as parameterization method to control the suction surface of the blades, which brings the following advantages:(A) significantly reducing design variables;(B) easy to ensure the mechanical strength of rotating blades;(C) better physical understanding;(D) easy to achieve smooth surface. The Improved Artificial Bee Colony(IABC) algorithm, which significantly increases the convergence speed and global optimization ability, is adopted to find the optimal result. A new engineering optimization tool is constructed by combining the surface parametric control method, the IABC algorithm, with a verified Computational Fluid Dynamics(CFD) simulation method, and it has been successfully applied in the aerodynamic optimization for a single-row transonic rotor(Rotor 37) and a single-stage transonic axialflow compressor(Stage 35). With the constraint that the relative change in the flow rate is less than0.5% and the total pressure ratio does not decrease, within the acceptable time in engineering, the adiabatic efficiency of Rotor 37 at design point increases by 1.02%, while its surge margin 0.84%,and the adiabatic efficiency of Stage 35 0.54%, while its surge margin 1.11% after optimization, to verify the effectiveness and potential in engineering of this new tool for optimization of axial compressor blade.     

基于型面节点的复合材料构件模具型面修正研究

针对复合材料在热压罐中固化变形造成的零件尺寸误差、带应力装配、降低疲劳寿命等长期困扰航空、航天工业的问题,研究复合材料固化变形的影响因素、作用机理等,并利用基准点的位置坐标,实现两曲面间的匹配,提出变形修正的算法和切实可行的修正手段,从而在模具设计时对模具型面做相应的补偿,减少试模、修模次数,实现复合材料固化变形的有效控制,达到复合材料精准制造的目的。     

基于响应面近似技术的平流层飞艇协同设计优化

针对平流层飞艇多学科设计优化问题,引入协同优化算法,分析基于响应面近似模型的协同优化方法CO/RSA的执行步骤和特点,并介绍响应面近似模型的构建方法;建立平流层飞艇各学科模型,并对学科间耦合关系进行分析;运用建立的气动/推进、结构、能源三个耦合子系统的学科分析模型和系统优化模型,以平流层飞艇总质量最小为优化目标,综合考虑浮重、推阻和能源平衡,采用CO/RSA方法对平流层飞艇进行设计优化.结果表明:所建立的平流层飞艇的MDO模型是合理的,CO/RSA算法应用于飞艇总体设计优化是有效的,研究结果可为平流层飞艇方案论证和方案设计提供参考.     

A100钢外螺纹椭圆超声滚压强化试验研究

A100钢有较高的疲劳抗力和显著的减重效果.在航空工业中,飞机起落架主要承力件正逐步采用A100钢,且主要承力件多采用螺纹联接.为了提高螺纹疲劳寿命,提出了超声振动滚压强化工艺方法,设计了外螺纹超声滚压强化装置,进行了螺纹超声滚压强化前后性能对比试验.利用X射线分析仪、维式硬度计、粗糙度仪和疲劳试验机,分别测量了螺纹超声滚压强化前后的残余应力、维氏硬度、表面粗糙度以及疲劳寿命.结果表明,超声滚压强化后牙底残余应力提高了70％,显微硬度提高了14％,粗糙度降低了51％,600MPa应力条件下寿命提高了5倍.     

原位自生TiB2/Al复合材料车削参数多目标优化方法

原位自生TiB2/Al复合材料具有密度小、比强度高、高耐磨等特点,在航空航天领域具有广泛的应用前景.主要针对TiB2/Al复合材料车削参数对表面粗糙度的影响进行探索性研究.首先,以车削速度、进给速度、车削深度为对象,基于单因素试验研究了车削参数控制域.进一步在控制域内设计正交试验,并基于试验结果研究了表面粗糙度与车削参数的映射关系,推导了材料去除率模型.最后,以表面粗糙度和材料去除率为优化目标,提出并研究了基于GA-Pareto的车削参数多目标优化方法,并通过试验验证了该方法的可行性和有效性.