SPACE LIFE SCIENCE IN 2000-2001

Chinese scientists studied some of the problems in the field of space life science and achieved success in the area during 2000-2001. Space biological experi ments were carried out in the orbit and the results of ground studies on protein crystallization, space radiation, space motion sickness were introduced in this paper. The influences of simulated weightlessness on the brain-function, the car diovascular, endocrine hormones, immunity, skeletal and muscle systems were presented. In addition, gravity medicine and space environment medicine, as well as countermeasures to space deconditioning, such as the traditional Chinese medicine, were also reported.     

中国航天医学进展

航天医学是随着载人航天事业的发展而兴起的一门特种医学学科、随着人类对太空的不断探索,从学科创建至今的短短几十年时间取得了巨大的发展,我国的载人航天工程于20世纪90年代初启动,但航天医学发展的历史却可追溯到50年代末,特别是近10年来,我国载人航天工程的启动为航天医学的发展带来了重大机遇,目前,我国首次载人航天飞行已获圆满成功,首飞航天员也已安全、健康地重返地球,航天医学专家们与航天员一同经受住了首次载人航天飞行的考验、本文简要介绍了我国航天医学的基础研究和应用研究,以及取得的进展,并展望了今后将面临的挑战和机遇。     

National Report on Space Medicine Progress

The development of Chinese manned space engineering has a great role in promoting the progress of Chinese space medicine. With the accelerated implementation of Chinese Space Station Program, China's space medicine has made fruitful achievements over the past three years. This report summarizes the major progress of Chinese space medicine in terms of basic research and space applications from 2016 to 2018.      

Space Materials Science in China: II. Ground-based Researches and Academic Activities

Activities of space materials science research in China have been continuously supported by two main national programs. One is the China Space Station (CSS) program since 1992, and the other is the Strategic Priority Program (SPP) on Space Science since 2011. In CSS plan in 2019, eleven space materials science experimental projects were officially approved for execution during the construction of the space station. In the SPP Phase II launched in 2018, seven pre-research projects are deployed as the first batch in 2018, and one concept study project in 2019. These pre-research projects will be cultivated as candidates for future selection as space experiment projects on the recovery of scientific experimental satellites in the future. A new apparatus of electrostatic levitation system for ground-based research of space materials science and rapid solidification research has been developed under the support of the National Natural Science Foundation of China. In order to promote domestic academic activities and to enhance the advancement of space materials science in China, the Space Materials Science and Technology Division belong to the Chinese Materials Research Society was established in 2019. We also organized scientists to write five review papers on space materials science as a special topic published in the journal Scientia Sinica to provide valuable scientific and technical references for Chinese researchers.      

Global approach to simulation: a gateway to long-term human presence in space.

The establishment of an autonomous European manned space capability is an objective set up by the ESA Council Meeting at the ministerial level, in 1985/1987. ESA's Long-Term Programme Office (LTPO), charged of the preparation of the programme for a European Manned Space Infrastructure (EMSI), started during 1988 to build up an intellectual framework in the domain of long-duration manned space missions. EMSI scope was eventually extended to embrace Moon/Mars missions and bases. Several exploratory studies on problems related to human factors in long-duration space missions were initiated by LTPO. The work of an ad-hoc group of experts (SIMIS Group) has been focused during 1989/1990 on the planning for simulation of such missions with a broad mandate, covering the physiological, psychological and operational aspects of long-duration exposure to microgravity and isolation/confinement. Preliminary results of SIMIS activities are reported. The HYDREMSI experiment, carried out in a terrestrial, analogous environment for 72 days during 1989, is described as an example of the envisaged simulations.     

航天“血淤症”及其防护措施

根据实验结果及国外有关资料证明,失重或模拟失重时人和动物血循环系统的紊乱和中医“血淤症”时的变化十分相似,提出我国“活血化淤”中药有可能成为防止失重血循环紊乱的一种有效药物的看法。     

Science Researches of Chinese Manned Space Flight

With the complete success of the 2nd stage of Chinese Manned Space Program (CMSP), several science researches have been performed on Tiangong-1 experimental spacelab, which was docked with three Shenzhou spaceships one after another. The China's real spacelab, Tiangong-2 will be launched in 2015, docked with a Shenzhou spaceship soon. After six months, it will be docked with the first Chinese cargo ship (Tianzhou-1). More space science researches, involving with space biology, fluid physics, fundamental physics, materials science, Earth science, astronomy and space environmental science, will be operated on Tiangong-2 spacelab, and crewed and cargo spaceships. Furthermore, the considerable large-scale space utilization of Shina's Space Station is planned. The research fields include yet not limited to space medicine and physiology, space life science and biotechnology, fluid physics and combustion in microgravity, space material science, and fundamental physics in microgravity, space astronomy, Earth science, space physics and space environment utilization, technology demonstration.      

A lunar laboratory

An international research laboratory can be established on the Moon in the early years of the 21st Century. It can be built using the transportation system now envisioned by the National Aeronautics and Space Administration, which includes a space station for Earth orbital logistics and orbital transfer vehicles for Earth-Moon transportation. A scientific laboratory on the Moon would permit extended surface and subsurface geological exploration; long-duration experiments defining the lunar environment and its modification by surface activity; new classes of observations in astronomy; space plasma and fundamental physics experiments; and lunar resource development. The discovery of a lunar source for propellants may reduce the cost of constructing large facilities in space and enhance other space programs such as Mars exploration.     

National Report on Space Medicine Progress in 2014—2016

The progress of China Spaceflight makes a great impetus for the development of space medicine. With the developing of China Space Station, the national space medicine has attained great achievements. In this paper, the basic research of Space Medicine and its application in China during 2014-2016 are briefly reviewed.      

空间增材制造技术的应用

中国空间站旨在进行大量在轨科学实验和空间应用研究,在轨保障是支持空间站在全寿命周期内完成载人航天任务的重要途径.传统地面制造及上行补给方式难以满足较大规模应用的需求,亟需一种创新性的保障模式突破资源瓶颈,空间增材制造技术具有极大的潜力实现即造即用的资源保障模式.本文根据空间增材制造技术的最新研究进展,结合中国空间站和载人深空探测任务需求,对空间增材制造技术的在轨应用模式进行分析,提出了中国空间增材制造技术未来发展所面临的问题和解决途径.      

Progress of Strategic Priority Program on Space Science

The Strategic Priority Program on Space Science in 2011-2017 (hereafter referred to as SPP I), which officially went ahead in 2011, marks that a new chapter of Chinese space endeavor has been opened. The 4 satellites, Wukong/DAMPE, SJ-10, Mozi/QUESS and Insight/HXMT, has been achieving promising scientific results since their launch, e.g., Wukong directly detected a break in the teraelectronvolt cosmic-ray spectrum of electrons and positrons. To enable the sustainable development of China's space science endeavor, the Strategic Priority Program Ⅱ on Space Science (hereafter referred to as SPP Ⅱ) was officially approved in late 2017. SPP Ⅱ includes 4 satellites-EP, ASO-S, SMILE and GECAM, Intensive Study of Future Space Science Missions, Advanced Research of Space Science Missions and Payloads, Space Science Mission Concept Research, and Data Analysis Research. Dedicated to exploring the unknown, the program is aiming to address scientific questions such as the origin and evolution of the universe and life, search for extraterrestrial life, and the impact of the Sun and the solar system on Earth and human development. Chinese space science community is committed to contributing to the progress of human civilization.      

HUMEX, a study on the survivability and adaptation of humans to long-duration exploratory missions, part I: lunar missions.

The European Space Agency has recently initiated a study of the human responses, limits and needs with regard to the stress environments of interplanetary and planetary missions. Emphasis has been laid on human health and performance care as well as advanced life support developments including bioregenerative life support systems and environmental monitoring. The overall study goals were as follows: (i) to define reference scenarios for a European participation in human exploration and to estimate their influence on the life sciences and life support requirements; (ii) for selected mission scenarios, to critically assess the limiting factors for human health, wellbeing, and performance and to recommend relevant countermeasures; (iii) for selected mission scenarios, to critically assess the potential of advanced life support developments and to propose a European strategy including terrestrial applications; (iv) to critically assess the feasibility of existing facilities and technologies on ground and in space as testbeds in preparation for human exploratory missions and to develop a test plan for ground and space campaigns; (v) to develop a roadmap for a future European strategy towards human exploratory missions, including preparatory activities and terrestrial applications and benefits. This paper covers the part of the HUMEX study dealing with lunar missions. A lunar base at the south pole where long-time sunlight and potential water ice deposits could be assumed was selected as the Moon reference scenario. The impact on human health, performance and well being has been investigated from the view point of the effects of microgravity (during space travel), reduced gravity (on the Moon) and abrupt gravity changes (during launch and landing), of the effects of cosmic radiation including solar particle events, of psychological issues as well as general health care. Countermeasures as well as necessary research using ground-based test beds and/or the International Space Station have been defined. Likewise advanced life support systems with a high degree of autonomy and regenerative capacity and synergy effects were considered where bioregenerative life support systems and biodiagnostic systems become essential. Finally, a European strategy leading to a potential European participation in future human exploratory missions has been recommended.     

Space Weather Service for Chinese Space Science Satellites

Strategic Priority Research Program on Space Science has gained remarkable achievements. Space Environment Prediction Center (SEPC) affiliated with the National Space Science Center (NSSC) has been providing space weather services and helps secure space missions. Presently, SEPC is capable to offer a variety of space weather services covering many phases of space science missions including planning, design, launch, and orbital operation. The service packages consist of space weather forecasts, warnings, and effect analysis that can be utilized to avoid potential space weather hazard or reduce the damage caused by space storms, space radiation exposure for example. Extensive solar storms that occurred over Chinese Ghost Festival (CGF) in September 2017 led to a large enhancement of the solar energetic particle flux at 1 AU, which affected the near Earth radiation environment and brought great threat to orbiting satellites. Based on the space weather service by SEPC, satellite ground support groups collaborating with the space Tracking, Telemetering and Command system (TT&C) team were able to take immediate measures to react to the CGF solar storm event.      

The effects of simulated microgravity on the seminiferous tubules of rats

Space flight has been shown to have many adverse effects on various systems throughout the body. Because the opportunity to place research animals on board a Space Shuttle or the International Space Station is infrequent, various techniques have been designed to simulate the effects of microgravity in Earth based laboratories. A commonly used technique is known as antiorthostatic suspension, also often referred to as hind limb suspension. In this technique the hind portion of the animal is raised so that its hind limbs are non-weight bearing. This places the animal in roughly a 30° head down tilt position. This results in cephalic fluid shifts similar to those seen in actual space flight. This technique has also been shown to mimic other physiological parameters that are affected during space flight. This study examined testicular tissue from rats subjected to a 7 day antiorthostatic suspension. This tissue was acquired through a tissue sharing program and some of the experimental animals were injected with Interleukin 1 receptor antagonist (IL-1ra) which was hoped to ameliorate some of the effects of antiorthostatic suspension. The injection of IL-1ra was not expected to have any effect on testicular tissue, however this tissue was included in the morphological and statistical analysis to conduct a more complete study. All tissues were embedded in paraffin, sectioned, and stained using standard H&E staining. The tissue was then qualitatively ranked according to the “health” of the seminiferous tubules. Our findings indicate that 7 days of antiorthostatic suspension had adverse effects on the tissue that comprises the walls of the seminiferous tubules. It has long been known that antiorthostatic suspension has deleterious effects on testicular tissue, however this research indicates that these effects occur much faster than indicated by previous researchers. This is a significant finding because it indicates that meaningful earth based studies in this area can be carried out in a shorter time span. This could result in more studies per year as well as saving money by avoiding longer than necessary animal suspensions. This is especially important as we enter an era when, without Space Shuttle, flight opportunities will become scarce. These antiorthostatic suspension studies indicate that space flight, even short duration spaceflight, may have harmful effects on the seminiferous tubules and blood-testis barrier of astronauts.     

Controlled Ecological Life Support Systems (CELSS) flight experimentation.

The NASA CELSS program has the goal of developing life support systems for humans in space based on the use of higher plants. The program has supported research at universities with a primary focus of increasing the productivity of candidate crop plants. To understand the effects of the space environment on plant productivity, the CELSS Test Facility (CTF) has been been conceived as an instrument that will permit the evaluation of plant productivity on Space Station Freedom. The CTF will maintain specific environmental conditions and collect data on gas exchange rates and biomass accumulation over the growth period of several crop plants grown sequentially from seed to harvest. The science requirements of the CTF will be described, as will current design concepts and specific technology requirements for operation in micro-gravity.     

抗磁性物质磁悬浮方法在空间生物学与生物技术中的应用

失重是特定空间运动条件下的重要环境物理特征之一, 一般以微重力环境来表示. 几十年来人类利用空间失重环境进行了多学科领域的科学研究与探索. 由于真实空间失重环境下科学实验机会稀少, 人类为研究空间失重环境或效应, 开发了多种地基的空间模拟实验技术方法. 然而, 对于空间生物学和空间生物技术研究而言, 已有的各种模拟实验技术手段在原理上和应用上均存在一定的局限性. 本文介绍了抗磁性物质在大梯度强磁场中的悬浮现象, 及将其用于模拟空间失重环境的方法与原理;简述了近年来利用抗磁性物质悬浮方法进行生物大分子晶体生长、分子细胞生物学及整体生物学等方面研究与应用的进展.      

Spaceflight hardware for conducting plant growth experiments in space: the early years 1960-2000.

The best strategy for supporting long-duration space missions is believed to be bioregenerative life support systems (BLSS). An integral part of a BLSS is a chamber supporting the growth of higher plants that would provide food, water, and atmosphere regeneration for the human crew. Such a chamber will have to be a complete plant growth system, capable of providing lighting, water, and nutrients to plants in microgravity. Other capabilities include temperature, humidity, and atmospheric gas composition controls. Many spaceflight experiments to date have utilized incomplete growth systems (typically having a hydration system but lacking lighting) to study tropic and metabolic changes in germinating seedlings and young plants. American, European, and Russian scientists have also developed a number of small complete plant growth systems for use in spaceflight research. Currently we are entering a new era of experimentation and hardware development as a result of long-term spaceflight opportunities available on the International Space Station. This is already impacting development of plant growth hardware. To take full advantage of these new opportunities and construct innovative systems, we must understand the results of past spaceflight experiments and the basic capabilities of the diverse plant growth systems that were used to conduct these experiments. The objective of this paper is to describe the most influential pieces of plant growth hardware that have been used for the purpose of conducting scientific experiments during the first 40 years of research.     

Porous Tube Plant Nutrient Delivery System development: a device for nutrient delivery in microgravity.

The Porous Tube Plant Nutrient Delivery System or PTPNDS (U.S. Patent #4,926,585) has been under development for the past six years with the goal of providing a means for culturing plants in microgravity, specifically providing water and nutrients to the roots. Direct applications of the PTPNDS include plant space biology investigations on the Space Shuttle and plant research for life support in Space Station Freedom. In the past, we investigated various configurations, the suitability of different porous materials, and the effects of pressure and pore size on plant growth. Current work is focused on characterizing the physical operation of the system, examining the effects of solution aeration, and developing prototype configurations for the Plant Growth Unit (PGU), the flight system for the Shuttle mid-deck. Future developments will involve testing on KC-135 parabolic flights, the design of flight hardware and testing aboard the Space Shuttle.     

Recent Advances in Observation and Research of the Chinese Meridian Project

The Chinese Meridian Space Weather Monitoring Project (Meridian Project) is a ground-based geospace monitoring chain in China. It consists of 15 ground-based observation stations located roughly along 120°E longitude and 30°N latitude. In recent two years, using data from the Meridian Project, significant progress has been made in space weather and space physics research. These advances are mainly in four aspects:regional characteristics of space environment above China or along 120°E meridian line, coupling between space spheres at different heights and different physical processes, space weather disturbance and its propagation along the meridian chain, and space weather effects on ground technical facilities.