Physics of Cosmic Microwave Background Anisotropies and Primordial Fluctuations

The physics of the origin and evolution of CMB anisotropies is described, followed by a critical discussion of the present status of cosmic parameter estimation with CMB anisotropies.     

Paramecium--a model system for studying cellular graviperception.

Experiments under varied gravitational accelerations as well as in density-adjusted media showed that sensation of gravity in protists may be linked to the known principles of mechanosensation. Paramecium, a ciliate with clear graviresponses (gravitaxis and gravikinesis) is an ideal model system to prove this hypothesis since the ciliary activity and thus the swimming behaviour is controlled by the membrane potential. It has also been assumed that the cytoplasmic mass causes a distinct stimulation of the bipolarly distributed mechano-sensitive K+ and Ca2+ ion channels in the plasma membrane in dependence of the spatial orientation of the cell. In order to prove this hypothesis, different channel blockers are currently under investigation. Gadolinium did not inhibit gravitaxis in Paramecium, showing that it does not specifically block gravireceptors. Further studies concentrated on the question of whether second messengers are involved in the gravity signal transduction chain. Exposure to 5 g for up to 10 min led to a significant increase in cAMP.     

Temperature Fluctuations,H II Region Abundances,and Primordial Helium

There is evidence for temperature fluctuations in Planetary Nebulae and in some Galactic H II regions. If such fluctuations occur in the low metallicity, extragalactic H II regions used to probe the primordial helium abundance, the derived 4He mass fraction, YP, could be systematically different from the true primordial value. Although this effect could be large, there are no data which allow us to estimate the size of the temperature fluctuations for the extragalactic H II regions. Therefore, we have explored this effect via Monte Carlo simulations of the data in which the abundances derived from a fiducial data set are modified by T chosen from a distribution with 0 T Tmax where Tmax is varied from 500 K to 4000 K.     

Subfreezing activity of microorganisms and the potential habitability of Mars' polar regions

The availability of water-ice at the surface in the Mars polar cap and within the top meter of the high-latitude regolith raises the question of whether liquid water can exist there under some circumstances and possibly support the existence of biota. We examine the minimum temperatures at which liquid water can exist at ice grain-dust grain and ice grain-ice grain contacts, the minimum subfreezing temperatures at which terrestrial organisms can grow or multiply, and the maximum temperatures that can occur in martian high-latitude and polar regions, to see if there is overlap. Liquid water can exist at grain contacts above about -20 degrees C. Measurements of growth in organisms isolated from Siberian permafrost indicate growth at -10 degrees C and metabolism at -20 degrees C. Mars polar and high-latitude temperatures rise above -20 degrees C at obliquities greater than ~40 degrees, and under some conditions rise above 0 degrees C. Thus, the environment in the Mars polar regions has overlapped habitable conditions within relatively recent epochs, and Mars appears to be on the edge of being habitable at present. The easy accessibility of the polar surface layer relative to the deep subsurface make these viable locations to search for evidence of life.     

Putative graviperception mechanisms of protists.

Many (if not all) free-living cells use the gravity vector for their spatial orientation (gravitaxis). Additional responses may include gravikinesis as well as changes in morphological and physiological parameters. Though using essentially different modes of locomotion, ameboid and ciliated cells seem to rely on common fundamental graviperception mechanisms. Uniquely in the ciliate family Loxodidae a specialized intracellular gravireceptor organelle has been developed, whereas in all other cells common cell structures seem to be responsible for gravisensing. Changes in direction or magnitude of acceleration (from 0 to 5 g) as well as experiments in density-adjusted media strongly indicate that either the whole cytoplasm or dense organelles like nuclei act as statoliths and open directly or via cytoskeletal elements mechano-sensitive ion channels in the cell membrane. A recent spaceflight experiment (S/MM-06) demonstrated that prolonged (9 d) actual weightlessness did not affect the ability of Loxodes to respond to acceleration stimuli. However, prolonged cooling (> or = l4 d, 4-10 degrees C) destroyed the ability for gravitactic orientation of Paramecium. This may reflect a profound effect either on the gravireceptor itself or on the gravity-signal processing. In gravity signalling the ubiquitous second messenger cAMP may be involved in acceleration-stimulus transduction.     

Transfer of space science and technology: A third world point of view

In contrast to the more common discussions on the how, where and when of transfer of space science and technology, we open a general discussion on the consequences of the space era in the developing countries and draw attention to the fact that space science and technology create a scientific and economic dependence on the industrially developed countries. Recommendations are made to render the space programs more beneficial to the Third World. These include : formation of local groups of high level space scientists and experts; instead of sophisticated transferred technology the use of space technologies appropriate to local economic and social status; services to the poorest fraction of the population and educational programs that protect the indigenous cultures.     

Comparative studies of the graviresponses of Paramecium and Loxodes.

Gravitactic protozoa offer advantages in studying how the gravity stimulus is perceived on the cellular level. By means of a slow rotating centrifuge microscope in space the acceleration thresholds for gravitaxis of Loxodes striatus and Paramecium biaurelia were determined: < or = 0.15 x g for Loxodes and 0.3 x g for Paramecium, indicating different sensitivities of these species. Neutral-buoyant densities of immobilized cells were determined using media of different densities, revealing densities of 1.03 to 1.035 g/cm3 for Loxodes and 1.04 g/cm3 to 1.045 g/cm3 for Paramecium. Behavioral studies revealed that gravitaxis of Loxodes persisted independent of the density of the medium. In contrast, negative gravitaxis of Paramecium was no longer measurable if the density of the medium approached the density of the cell. The results suggest that in the case of Loxodes gravity is perceived by an intracellular receptor and, in the case of Paramecium by its own mass via the pressure on the lower cell membrane.     

Effects of simulated weightlessness on fish otolith growth: Clinostat versus Rotating-Wall Vessel

Stimulus dependence is a general feature of developing sensory systems. It has been shown earlier that the growth of inner ear heavy stones (otoliths) of late-stage Cichlid fish (Oreochromis mossambicus) and Zebrafish (Danio rerio) is slowed down by hypergravity, whereas microgravity during space flight yields an opposite effect, i.e. larger than 1 g otoliths, in Swordtail (Xiphophorus helleri) and in Cichlid fish late-stage embryos. These and related studies proposed that otolith growth is actively adjusted via a feedback mechanism to produce a test mass of the appropriate physical capacity. Using ground-based techniques to apply simulated weightlessness, long-term clinorotation (CR; exposure on a fast-rotating Clinostat with one axis of rotation) led to larger than 1 g otoliths in late-stage Cichlid fish. Larger than normal otoliths were also found in early-staged Zebrafish embryos after short-term Wall Vessel Rotation (WVR; also regarded as a method to simulate weightlessness). These results are basically in line with the results obtained on Swordtails from space flight.     

Source Region of High and Low Speed Wind during the Spartan 201-05 Flight

The large-scale coronal magnetic fields of the Sun are believed to play an important role in organizing the coronal plasma and channeling the high and low speed solar wind along the open magnetic field lines of the polar coronal holes and the rapidly diverging field lines close to the current sheet regions, as has been observed by the instruments aboard the Ulysses spacecraft from March 1992 to March 1997. We have performed a study of this phenomena within the framework of a semi-empirical model of the coronal expansion and solar wind using Spartan, SOHO, and Ulysses observations during the quiescent phase of the solar cycle. Key to this understanding is the demonstration that the white light coronagraph data can be used to trace out the topology of the coronal magnetic field and then using the Ulysses data to fix the strength of the surface magnetic field of the Sun. As a consequence, it is possible to utilize this semi-empirical model with remote sensing observation of the shape and density of the solar corona and in situ data of magnetic field and mass flux to predict values of the solar wind at all latitudes through out the solar system. We have applied this technique to the observations of Spartan 201-05 on 1–2 November, 1998, SOHO and Ulysses during the rising phase of this solar cycle and speculate on what solar wind velocities Ulysses will observe during its polar passes over the south and the north poles during September of 2000 and 2001. In order to do this the model has been generalized to include multiple streamer belts and co-located current sheets. The model shows some interesting new results. This revised version was published online in August 2006 with corrections to the Cover Date.