Comparison of hindlimb unloading and partial weight suspension models for spaceflight-type condition induced effects on white blood cells

Animal models are frequently used to assist in the determination of the long- and short-term effects of space flight. The space environment, including microgravity, can impact many physiological and immunological system parameters. It has been found that ground based models of microgravity produce changes in white blood cell counts, which negatively affects immunologic function. As part of the Center of Acute Radiation Research (CARR), we compared the acute effects on white blood cell parameters induced by the more traditionally used animal model of hindlimb unloading (HU) with a recently developed reduced weightbearing analog known as partial weight suspension (PWS). Female ICR mice were either hindlimb unloaded or placed in the PWS system at 16% quadrupedal weightbearing for 4 h, 1, 2, 7 or 10 days, at which point complete blood counts were obtained. Control animals (jacketed and non-jacketed) were exposed to identical conditions without reduced weightbearing. Results indicate that significant changes in total white blood cell (WBC), neutrophil, lymphocyte, monocyte and eosinophil counts were observed within the first 2 days of exposure to each system. These differences in blood cell counts normalized by day 7 in both systems. The results of these studies indicate that there are some statistically significant changes observed in the blood cell counts for animals exposed to both the PWS and HU simulated microgravity systems.     

Life at the wedge: the activity and diversity of arctic ice wedge microbial communities

The discovery of polygonal terrain on Mars underlain by ice heightens interest in the possibility that this water-bearing habitat may be, or may have been, a suitable habitat for extant life. The possibility is supported by the recurring detection of terrestrial microorganisms in subsurface ice environments, such as ice wedges found beneath tundra polygon features. A characterization of the microbial community of ice wedges from the high Arctic was performed to determine whether this ice environment can sustain actively respiring microorganisms and to assess the ecology of this extreme niche. We found that ice wedge samples contained a relatively abundant number of culturable cells compared to other ice habitats (～10(5) CFU·mL(-1)). Respiration assays in which radio-labeled acetate and in situ measurement of CO(2) flux were used suggested low levels of microbial activity, though more sensitive techniques are required to confirm these findings. Based on 16S rRNA gene pyrosequencing, bacterial and archaeal ice wedge communities appeared to reflect surrounding soil communities. Two Pseudomonas sp. were the most abundant taxa in the ice wedge bacterial library (～50%), while taxa related to ammonia-oxidizing Thaumarchaeota occupied 90% of the archaeal library. The tolerance of a variety of isolates to salinity and temperature revealed characteristics of a psychrotolerant, halotolerant community. Our findings support the hypothesis that ice wedges are capable of sustaining a diverse, plausibly active microbial community. As such, ice wedges, compared to other forms of less habitable ground ice, could serve as a reservoir for life on permanently cold, water-scarce, ice-rich extraterrestrial bodies and are therefore of interest to astrobiologists and ecologists alike. .     

The german microgravity program: Objectives and present status

Within the space program of the Federal Republic of Germany the microgravity program in connection with the utilization of SPACELAB constitutes a central task which determines the long-term program concepts and also their relation to German participation in future ESA programs.The scientific preparatory programs under way for some years now have made further progress. Extensive flight experience and valuable scientific results were obtained on the basis of successful rocket pre-programs. The present paper describes the process in which scientific and organisational priorities are being defined for the planning and execution of the experimental programs.In order to obtain a sufficient number of flight opportunities, payloads for SPACE SHUTTLE missions, in particular under the NASA GAS Program, as well as experimental equipment such as the materials laboratory (MSDR) for FSLP are being developed. The German program focuses on preparing a German SPACELAB mission D1 planned for 1985, which is intended to verify the applicability and efficiency of manned research laboratories for industry and the scientific community. A second emphasis is on preparing the use of SHUTTLE-supported re-usable space platforms.     

A slotted waveguide array antenna from carbon fibre reinforced plastics for the European space SAR

This paper deals with the design of a Synthetic Aperture Radar (SAR)-antenna for the proposed European Remote Sensing Satellite. Electrical performance requirements and geometric constraints impose stringent conditions upon structural configuration and mechanical tolerances. A slotted waveguide array antenna is presented in a deployable configuration. It is composed of 5 radiating panels, and a foldable truss structure. Carbon fibre reinforced plastic material is used for structural elements and waveguides.     

The comptel experiment on the NASA Gamma-Ray Observatory

The imaging Compton telescope COMPTEL will be flown on the NASA Gamma-Ray Observatory at the beginning of the next decade. The instrument with its wide field of view and improved angular resolution will provide the first sky survey at MeV energies, as well as deep studies of galactic and extragalactic gamma-ray point sources and diffuse emission. The hardware preparations are close to completion, with calibrations to be done in 1987 prior to integration of the instrument onto the observatory carrying 3 other gamma ray detectors.     

Priorities in space for the USA

This article follows the story of Shuttle development, in the context of the history of the US space programme from Apollo to the Space Station. The Shuttle was chosen as one of a series of ‘space spectaculars’ and has proven to be prohibitively expensive and unreliable, practical only for a very limited number of specialized missions. The Space Station, too, cannot be economically supplied, even if the USA could afford to build it. The author concludes that NASA should cancel the Space Station and the replacement orbiter for Challenger, and engage on a major programme of launch vehicle development, independent of the US military. The aim should be a dramatic reduction of launch vehicle costs, making spaceflight practical, and a truly independent NASA which could restore the USA to space preeminence.     

Upgrade of the GOCE Level 1b gradiometer processor

This paper describes the upgrade of the GOCE Level 1b gradiometer processing as part of ESA’s Payload Data Segment (PDS). Four processing steps have been identified which can be improved: 1. The optimal determination of the angular rates of the satellite, based on a combination of star sensor and gradiometer data. This is the so-called angular rate reconstruction. 2. The optimal determination of the spacecraft’s attitude, again based on a combination of star sensor and gradiometer data. 3. The combination of data of all simultaneously available star sensors. And, 4. the calibration of the measured accelerations is improved by taking the time dependence of selected calibration parameters into account.     

Experiments on velocity augmentation of spherical flames by grids

Using spherical wire mesh screens with a wire diameter d and a mesh size l, an experimental study was carried out involving homogeneous mixtures of propane/air, ethylene/air, acetylene/air and with oxygen enriched air. Streak photographs of the processes were taken, yielding information on the flame propagation speeds inside and outside the screen. The ratio of the two speeds immediately before and after crossing the screen, α, can be interpreted as practically equivalent (for the same “heat release”) to the ratio of flame velocities relative to the unburned gas, i.e. Values of (α − 1) are correlated with the Reynolds number based on the wire thickness d, density and viscosity of the unburned gas and flame propagation speed inside the wire mesh. The experiments were repeated with two and three spheres of different diameters, e.g. inner screen 9 cm in diameter and outer screen 18 cm in diameter or three screens, 9, 13.5 and 18 cm, respectively. The second screen usually added a factor of 2 on the value of α. The third screen produced very little additional effect. The highest value of α we ever obtained for mixtures with air was about 12 (for acetylene/air). With oxygen enriched air the situation is quite different. If the flame velocity of the laminar flame relative to the unburned gas exceeds 2 m/sec, the value of α may increase up to a level corresponding to detonation.     

Atmospheric Science with InSight

In November 2018, for the first time a dedicated geophysical station, the InSight lander, will be deployed on the surface of Mars. Along with the two main geophysical packages, the Seismic Experiment for Interior Structure (SEIS) and the Heat-Flow and Physical Properties Package (HP³), the InSight lander holds a highly sensitive pressure sensor (PS) and the Temperature and Winds for InSight (TWINS) instrument, both of which (along with the InSight FluxGate (IFG) Magnetometer) form the Auxiliary Sensor Payload Suite (APSS). Associated with the RADiometer (RAD) instrument which will measure the surface brightness temperature, and the Instrument Deployment Camera (IDC) which will be used to quantify atmospheric opacity, this will make InSight capable to act as a meteorological station at the surface of Mars. While probing the internal structure of Mars is the primary scientific goal of the mission, atmospheric science remains a key science objective for InSight. InSight has the potential to provide a more continuous and higher-frequency record of pressure, air temperature and winds at the surface of Mars than previous in situ missions. In the paper, key results from multiscale meteorological modeling, from Global Climate Models to Large-Eddy Simulations, are described as a reference for future studies based on the InSight measurements during operations. We summarize the capabilities of InSight for atmospheric observations, from profiling during Entry, Descent and Landing to surface measurements (pressure, temperature, winds, angular momentum), and the plans for how InSight’s sensors will be used during operations, as well as possible synergies with orbital observations. In a dedicated section, we describe the seismic impact of atmospheric phenomena (from the point of view of both “noise” to be decorrelated from the seismic signal and “signal” to provide information on atmospheric processes). We discuss in this framework Planetary Boundary Layer turbulence, with a focus on convective vortices and dust devils, gravity waves (with idealized modeling), and large-scale circulations. Our paper also presents possible new, exploratory, studies with the InSight instrumentation: surface layer scaling and exploration of the Monin-Obukhov model, aeolian surface changes and saltation / lifing studies, and monitoring of secular pressure changes. The InSight mission will be instrumental in broadening the knowledge of the Martian atmosphere, with a unique set of measurements from the surface of Mars.     

Gamma-ray Lines From cr Source Regions

Gamma-ray lines arise from radioactivities produced in nucleosynthesis sites, and from deexcitation of nuclei which have been activated through energetic particle collisions. Since the bulk of nucleosynthesis activity relates to activities inside massive stars, both these processes are related to the likely sources of cosmic rays: Supernova remnants show radioactivity afterglows at time scales which bracket their likely phases of relevance as CR acceleration sites; ²⁶Al radioactivity may trace regions of intense wind interactions from groups of massive stars, and also encode information about the possible injection of matter into CR acceleration environments through interstellar dust grains. The status of -ray line measurements after the Compton Observatory mission is presented, with models and interpretations of current results, and the prospects of upcoming measurements.