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| 不同扫描条件下的小动物成像评估 | |
| 引用本文： | 贾鹏翔,王浩宇,闫镔,李磊,陈健,张锋,包尚联.不同扫描条件下的小动物成像评估[J].南京航空航天大学学报(英文版),2010,27(1):27-33. |
| 作者姓名： | 贾鹏翔 王浩宇 闫镔 李磊 陈健 张锋 包尚联 |
| 作者单位： | 1. 北京大学医学物理和工程北京市重点实验室,北京,100871,中国 2. 北京大学医学物理和工程北京市重点实验室,北京,100871,中国;国家数字交换系统工程技术研究中心,郑州,450002,中国 3. 国家数字交换系统工程技术研究中心,郑州,450002,中国 4. 北京大学医学物理和工程北京市重点实验室,北京,100871,中国;北京海思威科技有限公司,北京,100084,中国 |
| 基金项目： | Supported by the National Natural Science Foundation of China (60672104,10527003);;the Nation-al Basic Research Program of China (“973”Program)(2006CB705705);;the Joint Research Foundation of Beijing Mu-nicipal Commission of Education (JD100010607)~~ |
| 摘 要： | 为了评估在不同高压、滤光片厚度和管电流条件下的小动物成像，开发了一套动物成像微型CT装置，并在此装置上进行了不同高压、滤光片厚度、球管电流和曝光时间条件下的老鼠成像。以蒙特卡罗软件包PENELOPE为基础，开发了模拟本装置使用的X射线球管光谱的模型。同时，基于Matlab平台开发了计算X射线柬各种参数，包括平均能量、光强变化以及透射率变化等的软件平台。评估了各种影响微型CT成像的参数对信噪比（SDNR）的影响，并分析了成像参数选择与信噪比之间的关系。文中一系列针对小动物成像和图像质量评估的工具和方法可被广泛应用于小动物成像领域。 |
| 关 键 词： | 成像技术 微型CT 图像质量 蒙特卡罗模拟 |
EVALUATION OF SMALL ANIMAL IMAGING UNDER DIFFERENT SCAN CONDITIONS |
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| Jia Pengxiang,Wang Haoyu,Yan Bin,Li Lei,Chen Jian,Zhang Feng,Bao Shanglian.EVALUATION OF SMALL ANIMAL IMAGING UNDER DIFFERENT SCAN CONDITIONS[J].Transactions of Nanjing University of Aeronautics & Astronautics,2010,27(1):27-33. | |
| Authors: | Jia Pengxiang Wang Haoyu Yan Bin Li Lei Chen Jian Zhang Feng Bao Shanglian |
| Institution: | 1.Beijing City Key Lab of Medical Physics and Engineering/a>;Peking University/a>;Beijing/a>;100871/a>;P.R.China/a>;2.China National Digital Switching System Engineering and Technological Research Center/a>;Zhengzhou/a>;450002/a>;3.Handling Equipment Mechanical Department/a>;Academy of Military Transportation/a>;Tianjin/a>;300161/a>;4.Beijing Healthware Science & Technology Inc./a>;100084/a>;P.R.China |
| Abstract: | To evaluae small animal imaging with individual different high voltage,filter thickness and tube current,an animal X-ray micro-computed tomography (micro-CT) system based on panel detector is developed and a rat is scanned by using the system with individual high voltage,tube current,filter thickness,and exposure time.A model is presented based on the Monte Carlo code PENELOPE for generating the X-ray spectra of X-ray tube used in the micro-CT system.A platform developed based on Matlab allows for calculati... |
| Keywords: | imaging techniques micro-computed tomography (CT) imaging performance Monte Carlo simulation |
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