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Genetic differentiation induced by spaceflight treatment of Cistanche deserticola and identification of inter-simple sequence repeat markers associated with its medicinal constituent contents
Authors:Y Wu  DY Yang  PF Tu  YZ Tian  YH Guo  XM Wang  XB Li
Institution:1. School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, PR China;2. Modern Research Center of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100083, PR China;3. Forest and Desert Control Research Institute of Alxa League, Alxa League 750306, China;4. College of Agronomy and Biotechnology, China Agricultural University, Beijing 100094, PR China
Abstract:The dried, fleshy stems of Cistanche deserticola (Orobanchaceae) are popular tonics in Traditional Chinese Medicine (TCM) to treat the inability of kidney in expelling extra fluid in the body, causing fluid retention, and reform reproductive system. However, the wild plants of C. deserticola have become endangered due to habitat downsizing and over-harvesting for its medicinal usages. The present research was carried out for the following purposes: (1) promoting the space-breeding research; (2) providing molecular evidence for agricultural selective breeding; and (3) protecting this endangered herbal medicine and conserving its genetic resources.
Keywords:Cistanche deserticola  Spaceflight mutation  Inter-simple sequence repeat (ISSR)  Genetic diversity  Ecological restoration
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