Confocal microscopy in microgravity research. |
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| Authors: | A P Goede G J Brakenhoff C L Woldringh J W Aalders J P Imhof P van Kralingen W A Mels P Schreinemakers A Zegers |
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| Institution: | SRON, Laboratory for Space Research, Utrecht, The Netherlands. |
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| Abstract: | We have studied the application and the feasibility of confocal scanning laser microscopy (CSLM) in microgravity research. Its superior spatial resolution and 3D imaging capabilities and its use of light as a probe, render this instrument ideally suited for the study of living biological material on a (sub-)cellular level. In this paper a number of pertinent biological microgravity experiments is listed, concentrating on the direct observation of developing cells and cellular structures under microgravity condition. A conceptual instrument design is also presented, aimed at sounding rocket application followed by Biorack/Biolab application at a later stage. |
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