Emergence of adaptable systems and evolution of a translation device |
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Authors: | U Lehmann H Kuhn |
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Institution: | Max-Planck-Institut für Biophysikalische Chemie, (Karl-Friedrich Bonhoeffer-Institut), Molekularer Systemaufbau, D 3400, Göttingen-Nikolausberg, F.R.G. |
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Abstract: | An over-all organizational framework for the origin of life is outlined and attemps for realization are given. Evolution can be described as a process resulting in an increase of “knowledge” where knowledge is the number of carriers of genetic information discarded, on the average, until the evolutionary state under consideration is reached. A model for the evolution of a translation device, a crucial event in the origin of life, is described in detail. Aggregates of short polynucleotide strands in a hairpin conformation play a major role in this model. Experimental evidence for the selectivity of aggregation supports the idea of aggregates as error filters. Chromatographic separation as selection process during chemical evolution supports the model of the early translation device leading to the origin of the genetic code. |
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