| 心室肌动作电位的计算机建模与仿真 |
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| 引用本文： | 李安,揭克敏.心室肌动作电位的计算机建模与仿真[J].南昌航空工业学院学报,2004,18(2):56-64. |
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| 作者姓名： | 李安 揭克敏 |
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| 作者单位： | [1]南昌航空工业学院,江西南昌330034 [2]江西医学院,江西南昌330001 |
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| 摘 要： | 该文以H-H理论为基础，结合了最新离子通道的研究成果，对L-R Phase Ⅰ心室肌动作电位仿真模型进行了改进。根据MATLAB仿真结果分析，该模型比较完善，因为它不但具有较高的去极化速率，并且可以仿真和细胞外钾浓度有关的细胞电生理特征。
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| 关 键 词： | H-H理论 心室肌动作电位 跨膜电位 去极化速率 激活（失活）参数 |
| 文章编号： | 1001-4926(2004)02-0056-09 |
| 收稿时间： | 2004-01-10 |
| 修稿时间： | 2004年1月10日 |
The computer simulation of ventricular cardiac action potential |
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| LI An, JIE Ke - rain.The computer simulation of ventricular cardiac action potential[J].Journal of Nanchang Institute of Aeronautical Technology(Natural Science Edition),2004,18(2):56-64. |
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| Authors: | LI An JIE Ke - rain |
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| Institution: | 1. Nanchang Institute of Aeronautical Technology, Nanchang, Jiangxi 330034; 2. Jiangxi Medical Institute, Nanchang, Jiangxi 330001 |
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| Abstract: | Based on H-H formulation, the action potential model we present in this article has incorporated recent experimental findings of ion channels. We refer to the L-R Phase I Ventricular cardiac action potential model to set up our model, and certainly had made a modification according to our MATLAB emulation result. It shows that the new model is relatively perfect, because this model not only has higher depolarization rate, but also can be used to emulate the electro-biological characteristics of K+ concentration outside cells. |
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| Keywords: | H-H theory Ventricular cardiac action potential Transmembrane potential Depolarization rate Activation(Inactivation) parameter |
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