模拟失重时家兔耳廓微循环的变化

为了解失重时体液头向分布这一因素对微循环的影响,比较了两组兔(平卧组和头低位20°悬吊组)在实验7天中耳廓微循环和血液流变学指标的变化。结果证明体液头向分布可引起一定的微循环障碍,表现为毛细血管和细静脉管径变粗、流速减慢、血液在静脉中潴留、红细胞聚集、耳廓出血及立位时微血管调节功能发生改变,血液流变学指标也出现相应变化。本文分析了其中一些变化的起因,提出一些新的看法。 

Effects of Simulated Weightlessness on Rabbit's Ear Microcirculation

Experiments in two groups of rabbits (supine and head-down 20°) were done to observe the effects of cephalad redistribution of body fluid during simulated weightlessness on rabbit's ear microcirculation.Results showed that cephalad redistribution of body fluid can induce certain changes in microcirculation,i.e.increase of bore of capillaries and veinles,decrease of flow speed and blood pooling in veins,aggregetion of blood cells,patechae in the ears,and changes of regulative function of the microvessels during orthostasis.The indexes of blood rheology also had relative changes.The cause of certain changes were analysed,and some new ideas were postulated.A kind of specially designed rabbit cage and the method of observation of microcirculation through intact rabbit ears were also introduced.