Water and salt disturbances under condition of microgravity

Under conditions of microgravity severe alterations in body fluid composition and volume take place largely as a result of "cardiothoracic pooling" or headward shift of blood. Inappropriate endocrine, renal and cardiovascular responses result from the "misreading" of homeostatic signals by physiological receptors to produce an as yet incompletely defined syndrome under microgravitational conditions.