Anomalous phosphenes in ocular protontherapy |
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Authors: | E Khan F Maréchal R Dendale C Mabit V Calugaru L Desjardin L Narici |
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Institution: | 1. Institut de Physique Nucléaire IN2P3/CNRS, Univ. Paris Sud, 91406 Orsay Cedex, France;2. Institut Curie Centre de Protonthérapie d’Orsay, Campus Universitaire, Bat 101, 91898 Orsay Cedex, France;3. Department of Physics, University of Rome ‘Tor Vergata’, via della Ricerca Scientifica, 1, 00133 Rome, Italy |
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Abstract: | We have undertaken a clinical ground study of proton-induced light flashes (phosphenes). Patients treated at the Institut Curie – Centre de Protonthérapie in Orsay, France, received radiation therapy to cure ocular and skull-base cancers. Sixty percent of the patients treated for choroidal melanomas using 73 MeV protons report anomalous phosphenes. Delivering a radiation dose on the retina only is not sufficient to trigger the light flash. The present study may be the first indication of phosphenes triggered by protons of few tens of MeV. |
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Keywords: | Protons Phosphenes Light flashes ALTEA |
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