High magnetic gradient environment causes alterations of cytoskeleton and cytoskeleton-associated genes in human osteoblasts cultured in vitro |
| |
| Authors: | AR Qian PF Yang LF Hu W Zhang SM Di Z Wang J Han X Gao P Shang |
| |
| Institution: | Key Laboratory for Space Biosciences and Biotechnology, Institute of Special Environmental Biophysics, Faculty of Life Sciences, Northwestern Polytechnical University, Xi’an 710072, China |
| |
| Abstract: | The effects of a high magnetic gradient environment (HMGE) on the cytoskeletal architecture and genes associated with the cytoskeleton in osteoblasts (MC3T3-E1 and MG-63 cells) were investigated using confocal microscopy, real-time polymerase chain reaction (PCR) and atomic force microscopy (AFM). The findings showed that, under diamagnetic levitation conditions, the architecture and average height of the cytoskeleton and surface roughness in osteoblasts were dramatically altered. HMGE affects cytoskeleton arrangement and cytoskeleton-associated gene expression. |
| |
| Keywords: | High magnetic gradient environment Diamagnetic levitation Simulated weightlessness Cytoskeleton Osteoblast |
| 本文献已被 ScienceDirect 等数据库收录！ |
