| 中风患者康复期运动皮层网络的功能磁共振成像 |
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| 引用本文： | 郝冬梅,秦文,于春水,董会卿,刘楠.中风患者康复期运动皮层网络的功能磁共振成像[J].南京航空航天大学学报(英文版),2010,27(1):55-61. |
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| 作者姓名： | 郝冬梅 秦文 于春水 董会卿 刘楠 |
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| 作者单位： | 1. 北京工业大学生命科学与生物工程学院,北京100124,中国
2. 首都医科大学宣武医院,北京,100053,中国 |
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| 基金项目： | Supported by the National Natural Science Foundation of China (30670543)~~ |
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| 摘 要： | 为了了解中风患者康复期间大脑皮层功能激活区和运动皮层网络连通性的变化，以5名左侧大脑皮层有病变的患者为研究对象，在其发病后的第2，4，8和16周进行功能磁共振检查。利用SPM5软件对患者左、右手握拳任务下的图像进行分析，得到大脑运动皮层激活图。利用激活区域提取大脑运动皮层网络并计算其结构和功能特征以反映网络连通性。研究结果显示，在握拳任务下，损伤侧大脑半球与非损伤侧大脑半球相比，具有较多的激活区和较低的激活程度；运动皮层网络随着患者的逐渐康复表现出整体上较强的独立性和运动区域间较强的依赖性。研究有助于理解康复的机制。
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| 关 键 词： | 大脑 康复 中风 运动皮层网络 功能磁共振成像 |
MOTOR CORTEX NETWORKS IN STROKE PATIENTS DURING RECOVERY WITH FMRI |
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| Hao Dongmei,Qin Wen,Yu Chunshui,Dong Huiqing,Liu Nan.MOTOR CORTEX NETWORKS IN STROKE PATIENTS DURING RECOVERY WITH FMRI[J].Transactions of Nanjing University of Aeronautics & Astronautics,2010,27(1):55-61. |
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| Authors: | Hao Dongmei Qin Wen Yu Chunshui Dong Huiqing Liu Nan |
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| Institution: | 1.College of Life Science and Bioengineering/a>;Beijing University of Technology/a>;Beijing/a>;100124/a>;P.R.China/a>;2.Xuan Wu Hospital/a>;Capital Medical University/a>;100053/a>;P.R.China |
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| Abstract: | To investigate changes of functional activation areas of the cerebral cortex and the connectivity of motor cortex networks (MCNs) in stroke patients during the recovery,five patients with the infarct in their left hemispheres are recruited.Functional magnetic resonance imaging (fMRI) is performed in the second,fourth,eighth,and sixteenth weeks after the stroke.Images are analyzed using the professional software SPM5 to obtain the bilateral activation of the motor cortex in left and right handgrip tests.MCN ... |
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| Keywords: | brain recovery stroke motor cortex network functional magnetic resonance imaging (fMRI) |
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