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This paper reviews the medical operations performed on six European astronauts during seven space missions on board the space station Mir. These missions took place between November 1988 and August 1999, and their duration ranged from 14 days to 189 days. Steps of pre-flight medical selection and flight certification are presented. Countermeasures program used during the flight, as well as rehabilitation program following short and long-duration missions are described. Also reviewed are medical problems encountered during the flight, post-flight physiological changes such as orthostatic intolerance, exercise capacity, blood composition, muscle atrophy, bone density, and radiation exposure.  相似文献   
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Among the principal objectives of the Phase 1 NASA/Mir program were for the United States to gain experience working with an international partner, to gain working experience in long-duration space flight, and to gain working experience in planning for and executing research on a long-duration space platform. The Phase 1 program was to provide the US early experience prior to the construction and operation of the International Space Station (Phase 2 and 3). While it can be argued that Mir and ISS are different platforms and that programmatically Phase 1 and ISS are organized differently, it is also clear that many aspects of operating a long-duration research program are platform independent. This can be demonstrated by a review of lessons learned from Skylab, a US space station program of the mid-1970s, many of which were again “learned” on Mir and are being “learned” on ISS. Among these are optimum crew training strategies, on-orbit crew operations, ground support, medical operations and crew psychological support, and safety certification processes.  相似文献   
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Nazarenko  A.I.  Chobotov  V.A. 《Space Debris》1999,1(2):127-142
Initial orbital parameter errors are used to examine the miss distance between a spacecraft and an ensemble of tracked objects by a Monte Carlo-type analysis. The radial separation between orbits is evaluated and a keep-out zone is determined, which reduces the risk of collision to an acceptable level.An operational prediction methodology is suggested based on a catalog database, which identifies potentially hazardous approaches and computes the probability of collision for selected spacecraft. An example for the Mir Space Station is presented, which estimates the collision probability and the cross-sectional flux of cataloged objects for the time frame of interest. The results appear to be in good agreement with those of other space debris models.  相似文献   
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