DNA damage and repair in oncogenic transformation by heavy ion radiation.

Energetic heavy ions are present in galactic cosmic rays and solar particle events. One of the most important late effects in risk assessment is carcinogenesis. We have studied the carcinogenic effects of heavy ions at the cellular and molecular levels and have obtained quantitative data on dose-response curves and on the repair of oncogenic lesions for heavy particles with various charges and energies. Studies with repair inhibitors and restriction endonucleases indicated that for oncogenic transformation DNA is the primary target. Results from heavy ion experiments showed that the cross section increased with LET and reached a maximum value of about 0.02 micrometer2 at about 500 keV/micrometer. This limited size of cross section suggests that only a fraction of cellular genomic DNA is important in radiogenic transformation. Free radical scavengers, such as DMSO, do not give any effect on induction of oncogenic transformation by 600 MeV/u iron particles, suggesting most oncogenic damage induced by high-LET heavy ions is through direct action. Repair studies with stationary phase cells showed that the amount of reparable oncogenic lesions decreased with an increase of LET and that heavy ions with LET greater than 200 keV/micrometer produced only irreparable oncogenic damage. An enhancement effect for oncogenic transformation was observed in cells irradiated by low-dose-rate argon ions (400 MeV/u; 120 keV/micrometer). Chromosomal aberrations, such as translocation and deletion, but not sister chromatid exchange, are essential for heavy-ion-induced oncogenic transformation. The basic mechanism(s) of misrepair of DNA damage, which form oncogenic lesions, is unknown.     

飞机燃油油量测量及姿态误差修正方法

提出了一种基于 CAD技术的航空燃油油量实时测量方法。采用三维实体造型技术 ,建立了某飞机机翼油箱模型 ,利用油量传感器的输出值及飞机姿态信息 ,对燃油油量进行实时测量及姿态误差修正。     

ERG理论在房地产营销中的应用

在房地产营销中，我们根据ERG多层次需求理论，从S．T．P战略出发，将房地产市场进行细分（Segmentation）后，分析目标客户群（Targeting）并实施产品定位（Positioning）。通过进行4P营销组合，即满意的产品（Product）、适当的价格（Price）、有效的分销渠道（Place）和促销手段（Promotion）最终达到顾客满意。     

民航机场建立呼叫中心的作用及实施对策

论文介绍了呼叫中心的技术原理，在分析民诱机场商务活动的现状的基础上，阐述了呼叫中心的特点及其在机场经营业务中的作用，提出了民航机场呼叫中心的模型，最后论述了民航机场实施呼叫中心的对策。     

胶州湾环境污染—卫星遥感信息分析

陆地卫星主题绘图仪(TM)图象和我国国土普查卫星全景相机照片解译分析与现场调查表明,胶州湾东岸工业废水污染相当严重,主要污染源集中在海泊河、李村河、娄山河以及沧口区沿海一线,污染水带宽达4～7km,在落潮流携带下扩散至湾口外海。由青岛碱厂排污形成的“白滩”污染区现有面积为0.53km~2。青岛市大气污染严重,源自市区的烟羽宽达14km,顺风飘逸远达30km,势必造成酸雨等灾害。     

光栅信号时钟脉冲细分的误差分析

简介时钟脉冲细分技术的原理，着重分析其细分误差因素，给出了计算实际最大细分数的理论公式，并论述了光栅最大运动速度、时钟脉冲分频数和实际最大细分数之间的关系，对光栅信号时钟脉冲细分系统的参数设计具有指导意义。     

气动力星座保持的闭环控制研究

本文研究了利用气动力进行星座保持的闭环控制问题。提出了一种改进的半全局指数收敛闭环控制律，对于指定的任意大的有界域，利用不变集定理论上证明了该控制律的稳定性和抗干扰性，又提出了双ε法以提高响应速度。     

三轴稳定遥感卫星姿控系统故障情况下的系统重构

论述三轴对地稳定遥感卫星姿控系统中部分轮子或部分陀螺故障情况下的姿控系统重构。文中论述了只在俯仰通道有一偏置动量轮正常工作，而滚动和偏航通道轮子故障条件下的系统重构。另外还论述了偏航陀螺故障，姿控系统其它部件正常情况下，控制系统采用Whecon原理与PIM控制相结合的设计。以上两种系统重构拟用于实际系统中，经过数学仿真验证，姿控系统在故障情况下能够完成基本任务。     

Flutter analysis of an airfoil with bounded random parameters in incompressible flow via Gegenbauer polynomial approximation

The effects of parameter uncertainty on the flutter characteristics of a two-dimensional airfoil in an incompressible flow were investigated through Gegenbauer polynomial approximation. The uncertain parameters, such as the linear and cubic pitch stiffness coefficients are modeled as bounded random variables with λ-PDFs (probability density functions). With the aid of Gegenbauer polynomial approximation, the two-dimensional stochastic airfoil system is transformed at first into its equivalent deterministic one. Then the Hopf-bifurcation point is determined through the equivalent deterministic system, and the onset of the flutter, together with the flutter frequency against the probability density distribution parameter and the intensity of the random variable is explored. In addition, the ranges of the peak pitch and plunge responses against the flight speed and the PDFs of the peak pitch response are obtained. Numerical results show how the probability density distribution parameters and the intensities of random parameters affect the flutter onset speed, flutter angular frequency, the upper and lower boundaries of peak responses, and the PDFs of peak responses.     

CDMA网络中CQT定点测试排除掉话故障分析

CDMA网络的建设过程中由于规划、硬件问题、软件参数设置等造成个别地区通话质量差、掉话率高等问题,网络优化人员可以通过后台参数分析、后台信令分析、现场测试等辅助手段排除网络故障。在故障发生地点通过现场定点测试定位故障是处理此类用户故障投诉的较好方法。论文尝试通过测试软件CQT定点测试法分析CDMA网络中典型掉话故障。