The influence of microgravity on invasive growth in Saccharomyces cerevisiae

This study investigates the effects of microgravity on colony growth and the morphological transition from single cells to short invasive filaments in the model eukaryotic organism Saccharomyces cerevisiae. Two-dimensional spreading of the yeast colonies grown on semi-solid agar medium was reduced under microgravity in the Σ1278b laboratory strain but not in the CMBSESA1 industrial strain. This was supported by the Σ1278b proteome map under microgravity conditions, which revealed upregulation of proteins linked to anaerobic conditions. The Σ1278b strain showed a reduced invasive growth in the center of the yeast colony. Bud scar distribution was slightly affected, with a switch toward more random budding. Together, microgravity conditions disturb spatially programmed budding patterns and generate strain-dependent growth differences in yeast colonies on semi-solid medium.     

The Swift Ultra-Violet/Optical Telescope

The Ultra-Violet/Optical Telescope (UVOT) is one of three instruments flying aboard the Swift Gamma-ray Observatory. It is designed to capture the early (∼1 min) UV and optical photons from the afterglow of gamma-ray bursts in the 170–600 nm band as well as long term observations of these afterglows. This is accomplished through the use of UV and optical broadband filters and grisms. The UVOT has a modified Ritchey–Chrétien design with micro-channel plate intensified charged-coupled device detectors that record the arrival time of individual photons and provide sub-arcsecond positioning of sources. We discuss some of the science to be pursued by the UVOT and the overall design of the instrument.     

The IMAGE Observatory

The Imager for Magnetopause-to-Aurora Global Exploration (IMAGE) mission will be the first of the new Medium-class Explorer (MIDEX) missions to fly. IMAGE will utilize a combination of ultraviolet and neutral atom imaging instruments plus an RF sounder to map and image the temporal and spatial features of the magnetosphere. The eight science sensors are mounted to a single deckplate. The deckplate is enveloped in an eight-sided spacecraft bus, 225 cm across the flats, developed by Lockheed Martin Missiles and Space Corporation. Constructed of laminated aluminum honeycomb panels, covered extensively by Gallium Arsenide solar cells, the spacecraft structure is designed to withstand the launch loads of a Delta 7326-9.5 ELV. Attitude control is via a single magnetic torque rod and passive nutation damper with aspect information provided by a star camera, sun sensor, and three-axis magnetometer. A single S-band transponder provides telemetry and command functionality. Interfaces between the self-contained payload and the spacecraft are limited to MIL-STD-1553 and power. This paper lists the requirements that drove the design of the IMAGE Observatory and the implementation that met the requirements.