The application of micro-CT in monitoring bone alterations in tail-suspended rats in vivo

Osteopenia is a pathological process that affects human skeletal health not only on earth but also in long-time spaceflight. Micro-computed tomography (micro-CT) is a nondestructive method for assessing both bone quantity and bone quality. To investigate the characteristics of micro-CT on evaluating the microgravity-induced osteopenia (e.g. early detection time and the sensitive parameters), the bone loss process of tail-suspended rats was monitored by micro-CT in this study. 8-Week-old female Sprague Dawley rats were divided into two groups: tail suspension (TS) and control (CON). Volumetric bone mineral density (vBMD) and microstructure of the femur and tibia were evaluated in vivo by micro-CT at 0, 7, 14, 22 days. Biomechanical properties of the femur and tibia were determined by three-point bending test. The ash weight of bone was also investigated. The results showed that (1) bone loss in the proximal tibia appeared earlier than in the distal femur. (2) On day 7, the percent bone volume (BV/TV) of the tibia 15.44% decreased significantly, and the trabecular separation (Tb.Sp) 30.29% increased significantly in TS group, both of which were detected earlier than other parameters. (3) Biomechanical properties (e.g. femur, −22.4% maximum load and −23.75% Young’s modulus vs. CON) and ash weight of the femur and tibia decreased significantly in the TS group in comparison to CON group. (4) vBMD of the femur and tibia were clearly related to bone ash and dry weight (r = 0.75–0.87, p < 0.05). (5) BV/TV of both femur and tibia were clearly related to maximum load and Young’s modulus (r = 0.66–0.87, p < 0.05). Similarly, trabecular vBMD and BV/TV of the femur and tibia were clearly related to Young’s modulus (r = 0.73–0.89, p < 0.05). These indicated that BV/TV and Tb.Sp were more sensitive than other parameters for evaluating bone loss induced by tail suspension, moreover, trabecular vBMD and other parameters might be used to evaluate bone strength. Therefore, micro-CT is a reliable and sensitive method for predicting unloading-induced bone loss in small animals.     

激光焊接带口盖加筋壁板剪切性能分析

针对双光束激光焊接带口盖加筋壁板开展了剪切稳定性试验,分析了带口盖加筋壁板在受剪状态下的屈曲载荷、屈曲形式、后屈曲承载能力及破坏形式。建立了壁板与剪切夹具的有限元模型,对壁板的剪切失稳形式及后屈曲承载能力进行仿真计算,并探究了口盖对加筋壁板的承载能力、应力变化及面外变形的影响。结果表明:带口盖加筋壁板在剪切状态下,当屈曲比达到1.95时,加筋壁板进入后屈曲,最终破坏载荷约为屈曲载荷的2.98倍。仿真与试验得到的载荷-位移曲线较为吻合,有限元法得到的屈曲载荷和破坏载荷与试验平均值误差分别为8.7%、1.02%。开口壁板的承载能力及刚度均下降,螺栓紧固口盖对加筋壁板的应力与面外变形影响较大。      

δ0.05mm薄钢带力学性能测试方法研究

研究了拉伸速率、试样类型、试样表面状态对δ0.05mm薄钢带力学性能测试的影响,通过数据对比,结果表明：拉伸速率对薄钢带的力学性能测试结果影响并不大,而试样的类型和试样的表面状态对力学性能测试结果有很大的影响;表面无缺陷的哑铃型试样可以满足检测要求,提高钢带检验一次合格率。     

两种不同注水方式的燃气蒸汽式发射系统内弹道性能比较

对逐渐注水冷却与集中注水冷却燃气蒸汽式发射动力系统进行了研究,着重分析不同注水方式下发射动力系统结构的差异、注水的特点及其对发射内弹道性能的影响,在此基础上开发出一套用于预估和比较不同注水方式下发射系统内弹道性能的系统化程序。计算结果显示,不同注水方式下导弹在发射筒内运动加速度、速度、位移随时间变化的规律和发射筒内工质气体状态参数随时间变化的规律,为燃气蒸汽式发射系统的设计和方案选择提供参考依据。     

增塑剂对双基推进剂动态力学性能的影响

用动态热机械分析方法考察了NC含氮量、液态含能增塑剂DDXZ和NG以及固态增塑剂P对双基推进剂动态力学性能的影响.双基推进剂具有高低温2个力学松弛过程,即α-转变和β-转变.发现β-转变的tanδ峰温随NC含氮量的增加而下降,混合液态增塑剂NG/DDXZ中NG的比例增大时,β-转变的tanδ峰温上升,α-转变中tanδ峰温和峰值都提高.随着固态增塑剂P含量的增加,高温α-转变的tanδ峰温下降,峰值增大,柔量亦增大.     

高可靠小条件数压缩感知叶尖定时信号辨识

为增强基于任意角度压缩感知(CS)叶尖定时信号(BTT)重构的稳定性,采用小生境微种群遗传算法提出了基于小条件数的高稳定性传感器安装布置方法。研究发现:任意角度CS的恢复矩阵条件数越小,不同信噪比下同步和非同步振动信号重构误差越趋于稳定在较低范围,优化后发现条件数为1的排布方案下,相邻传感器角度间隔趋向于均布2m取K的形式。利用条件数为1的矩阵冗余特性,设计了高可靠性的传感器排布方案,数值试验和有限元仿真验证表明叶尖定时系统在失效一个传感器的情况下仍可稳定得到准确的重构结果。在信噪比为5 dB时,冗余排布相比参考排布的主倍频幅值重构误差降低4.4%以上,验证了采用最小条件数排布的任意角度CS信号辨识方法在噪声及传感器失效情况下仍可保证BTT测量结果的有效性和可靠性。      

纳米材料拉伸装置的设计及定量化分析

以压电陶瓷为主体设计了一种用于单体纳米材料原位拉伸变形实验的装置,为了实现力学性能的定量化测量,在该装置中加装了用于测量力的悬臂梁针尖,通过悬臂梁针尖的变形可实现纳米材料力学性能测试中的定量化性能测试.利用该自主设计的纳米材料拉伸仪,以利用热蒸发法制备的非晶氧化硅纳米线为实例,在光学显微镜和扫描电子显微镜下进行了原位力学性能测试实验.实验结果显示:该原位纳米材料拉伸装置可以有效地实现纳米材料的拉伸变形操作,同时对施加在材料样品本身上的力学信号给出定量化的结果.      

三(叠氮乙酰氧甲基)硝基甲烷的合成与性能

以三羟甲基硝基甲烷为原料,经酯化、叠氮化两步反应合成出三(叠氮乙酰氧甲基)硝基甲烷,总收率为83.0%。利用红外光谱、核磁共振、元素分析表征了其结构。探讨了叠氮化反应的影响因素,确定其最佳反应条件为:Na N3摩尔加入量为理论值的1.10倍,混合溶剂中水占总体积的10%~25%,反应时间1 h。测试得到TMNTA的密度为1.45 g/cm3,热分解温度为235.7℃,玻璃化转变温度为-26.23℃,撞击感度H50=44.7 cm(落锤2 kg),爆炸概率4%(摆角66°)。