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41.
T.C. Slaba G.D. Qualls M.S. Clowdsley S.R. Blattnig S.A. Walker L.C. Simonsen 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2010
To estimate astronaut health risk due to space radiation, one must have the ability to calculate various exposure-related quantities that are averaged over specific organs and tissue types. Such calculations require computational models of the ambient space radiation environment, particle transport, nuclear and atomic physics, and the human body. While significant efforts have been made to verify, validate, and quantify the uncertainties associated with many of these models and tools, relatively little work has focused on the uncertainties associated with the representation and utilization of the human phantoms. In this study, we first examine the anatomical properties of the Computerized Anatomical Man (CAM), Computerized Anatomical Female (CAF), Male Adult voXel (MAX), and Female Adult voXel (FAX) models by comparing the masses of various model tissues used to calculate effective dose to the reference values specified by the International Commission on Radiological Protection (ICRP). The MAX and FAX tissue masses are found to be in good agreement with the reference data, while major discrepancies are found between the CAM and CAF tissue masses and the reference data for almost all of the effective dose tissues. We next examine the distribution of target points used with the deterministic transport code HZETRN (High charge (Z) and Energy TRaNsport) to compute mass averaged exposure quantities. A numerical algorithm is presented and used to generate multiple point distributions of varying fidelity for many of the effective dose tissues identified in CAM, CAF, MAX, and FAX. The point distributions are used to compute mass averaged dose equivalent values under both a galactic cosmic ray (GCR) and solar particle event (SPE) environment impinging isotropically on three spherical aluminum shells with areal densities of 0.4 g/cm2, 2.0 g/cm2, and 10.0 g/cm2. The dose equivalent values are examined to identify a recommended set of target points for each of the tissues and to further assess the differences between CAM, CAF, MAX, and FAX. It is concluded that the previously published CAM and CAF point distributions were significantly under-sampled and that the set of point distributions presented here should be adequate for future studies involving CAM, CAF, MAX, or FAX. It is also found that the errors associated with the mass and location of certain tissues in CAM and CAF have a significant impact on the mass averaged dose equivalent values, and it is concluded that MAX and FAX are more accurate than CAM and CAF for space radiation analyses. 相似文献
42.
回顾了当前驾驶舱设计中人因工程学的研究进展,重点探讨了人因工程学研究方法在飞机驾驶舱空间布局设计中的具体应用,总结了设计中需要遵循的原则,并对驾驶舱设计进一步的研究提出了若干建议。 相似文献
44.
Sofya A. Ushakova Alexander A. Tikhomirov Valentin N. Shikhov Jean-Bernard Gros Tamara K. Golovko Igor V. Dal’ke Ilya G. Zakhozhii 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2013
The main objective of a life support system for space missions is to supply a crew with food, water and oxygen, and to eliminate their wastes. The ultimate goal is to achieve the highest degree of closure of the system using controlled processes offering a high level of reliability and flexibility. Enhancement of closure of a biological life support system (BLSS) that includes plants relies on increased regeneration of plant waste, and utilization of solid and liquid human wastes. Clearly, the robustness of a BLSS subjected to stress will be substantially determined by the robustness of the plant components of the phototrophic unit. The aim of the present work was to estimate the heat resistance of two plants (wheat and lettuce) grown on human wastes. Human exometabolites mineralized by hydrogen peroxide in an electromagnetic field were used to make a nutrient solution for the plants. We looked for a possible increase in the heat tolerance of the wheat plants using changes in photosynthetically active radiation (PAR) intensity during heat stress. At age 15 days, plants were subjected to a rise in air temperature (from 23 ± 1 °C to 44 ± 1 °С) under different PAR intensities for 4 h. The status of the photosynthetic apparatus of the plants was assessed by external СО2 gas exchange and fluorescence measurements. The increased irradiance of the plants during the high temperature period demonstrated its protective action for both the photosynthetic apparatus of the leaves and subsequent plant growth and development. The productivity of the plants subjected to temperature changes at 250 W m−2 of PAR did not differ from that of controls, whereas the productivity of the plants subjected to the same heat stress but in darkness was halved. 相似文献
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46.
对2023年3月美国国家航空航天局(NASA)发布的2024财年预算申请进行分析和梳理。分析了NASA在2024财年预算概况以及深空探索系统、空间运行、空间技术、科学领域的重点部署情况。研究并讨论了NASA 2024财年预算案积极响应NASA最新战略规划,预算案对重要领域的重大影响,美国严峻通胀态势以及预算不确定性对NASA未来发展走向的潜在影响等关键问题。 相似文献
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民机客户服务人才对我国民机产业发展具有重要影响,其发展建设已纳入国家“十二五冶人才建设规划。介绍了全球顶尖民机制造商波音与空客的客户服务人力资源现状,总结了其客户服务人才队伍的培养措施,最后结合中国商飞公司实际,从招聘、培养、激励及管理等方面提出了培养公司客户服务人才队伍的建议。 相似文献
50.
通过模拟来研究微重力对hMSC向成骨细胞分化的影响,并利用相关信号通路的激活剂或抑制剂来调节这一分化过程.研究结果表明,在成骨细胞分化诱导条件下,微重力降低了hMSC向成骨细胞定向分化的能力,并且成骨细胞标记性基因的表达明显降低, Runt相关转录因子2(Ruax2)的表达受到抑制.相反,过氧化物酶体增殖激活受体γ(PPARγ2)的表达则增加.同时,微重力也降低了ERK的磷酸化水平,而增加了p38MAPK的磷酸化水平.使用p38MAPK的抑制剂SB203580能够抑制p38MAPK的磷酸化,但不能降低PPARγ2的表达水平.骨形态发生蛋白(BMP)能增加Runx2的表达水平.成纤维细胞生长因子2(FGF2)增加了ERK的磷酸化水平,但也不能显著增加成骨细胞标记性基因的表达水平.采用BMP,FGF2和SB203580三种因子组合来调控微重力下的成骨细胞分化能力,结果表明三者的协同作用能显著逆转微重力对成骨细胞定向分化的生物学效应.研究结果还说明,模拟微重力应该是通过不同的细胞信号通路来抑制成骨细胞分化和提升脂肪细胞分化的. 相似文献