X-ray induced alterations in the differentiation and mineralization potential of murine preosteoblastic cells

To evaluate the effects of ionizing radiation (IR) on murine preosteoblastic cell differentiation, we directed OCT-1 cells to the osteoblastic lineage by treatment with a combination of β-glycerophosphate (β-GP), ascorbic acid (AA), and dexamethasone (Dex). In vitro mineralization was evaluated based on histochemical staining and quantification of the hydroxyapatite content of the extracellular bone matrix. Expression of mRNA encoding Runx2, transforming growth factor β1 (TGF-β1), osteocalcin (OCN), and p21^CDKN1A was analyzed. Exposure to IR reduced the growth rate and diminished cell survival of OCT-1 cells under standard conditions. Notably, calcium content analysis revealed that deposition of mineralized matrix increased significantly under osteogenic conditions after X-ray exposure in a time-dependent manner. In this study, higher radiation doses exert significant overall effects on TGF-β1, OCN, and p21^CDKN1A gene expression, suggesting that gene expression following X-ray treatment is affected in a dose-dependent manner. Additionally, we verified that Runx2 was suppressed within 24 h after irradiation at 2 and 4 Gy. Although further studies are required to verify the molecular mechanism, our observations strongly suggest that treatment with IR markedly alters the differentiation and mineralization process of preosteoblastic cells.     

Research on a complex CME event including Hα, LASCO, radio and MDI observations

We present our research on a fast and decelerating partial halo coronal mass ejection (CME) event detected in multi-wavelengths in the chromosphere and the corona on 14 October, 1999. The event involved a whole complex active area which spanned more than 40° of heliolongitude. It included a strong solar flare (XI/1N) and a complex eruptive filament within an active region of the entire complex. Especially, several radio sources were detected in the decimetric range prior to the CME by the Nançay Radioheliograph (NRH). A linear force-free field extrapolation of the Michelson Doppler Imager (MDI) magnetogram was performed to calculate the magnetic topology of the complex prior to the triggering of the event. The presence of a coronal null point combined with the occurrence of two distant and nearly simultaneous radio sources put strong arguments in favor of the generalized breakout model for the triggering of the eruption. The analysis of the subsequent development of the event suggests that large interconnecting loops were ejected together with the CME.     

Faster conception of radically innovative systems: the strategic and organizational challenge for space agencies

Are space agencies able to reform the way they are organized? Attempts to reduce the time it takes to conceive new systems and adapt project management while fostering innovation have so far shown mixed results. In this paper, we describe some of the intellectual, strategic and organizational challenges the agencies are about to face in the coming years: managing the ever growing complexity of space systems; defining a knowledge-based strategy as the basis of a renewed organization; and assuming a central role in the innovation process in relation to industry. This thesis is illustrated with a case study of the CNES Microsatellite Myriade program.     

Space traffic control: a view of the future

This paper provides an overview of a system for providing reliable, ongoing, timely situational awareness services to satellite operators. Such services would include close approach warnings, warnings of potential radio frequency interference, and other offerings designed to help make operators aware of possible threats to the safe operation of their spacecraft and measures they can take to lessen these threats. The paper discusses current trends, proposes operational requirements, and speculates on the type of organization that may emerge to provide space traffic control services. It highlights how the detailed information required for such services may affect the evolution of the use of space.     

振动对空间光通信系统误码率影响的分析

在空间光通信系统中，由于卫星平台的振动，使得光发射机发生振动，从而对通信系统的误码率产生影响，本文针对光射光束为高斯光束时，振动对误码率的影响问题进行研究。结果表明，在振动时不仅振幅影响着误码率，而且波长也对误码率有影响，但通信距离对误码率的影响不大，一般可以忽略。     

深空探测通信技术发展趋势及思考

阐述了深空探测通信的重要地位和意义，就深空探测通信中的主要问题和特点开展论述，分析了深空探测通信的国内外研究现状。提出了利用地球静止轨道卫星编队的方法构建我国自主的天基连续测控和通信系统的构想，并以月球为中继、利用地月系统内的拉格朗日点开展深空探测。建议当前开展深空探测通信中星际互联网络体系结构、高效信道编码技术和空间协议研究的构想。     

基于CCSDS空间数据链路安全协议的星载遥控认证保护

在国际空间数据系统咨询委员会(CCSDS)规定的空间遥控系统数据传输体制下,对星载遥控认证保护进行了研究.选择了遥控数据认证保护层次,并设计了认证保护数据范围.针对上行遥控的认证保护机制与国际空间数据系统咨询委员会的空间遥控链路命令操作过程(COP-1)之间存在的"闭锁"风险,设计了重传请求保护机制.基于空间数据链路安...     

中国空间技术成就斐然——纪念东方红1号卫星发射成功30周年

从1970年至1999年,中国已用长征系列运载火箭进行了68次航天发射,累计发射了84颗人造地球卫星(其中国产卫星52颗、国外卫星32颗)和1艘无人状态的试验飞船,发射成功率约85％。现今,中国对空间技术体系的认识已得到深化,中国的航天器进入太空技术已位居世界前列,中国的航天信息应用技术已取得显著效益。     

深空探测器运行轨道的基本性态

要成功地发射一个深空探测器进入目标轨道,相应的运行过程基本上涉及3个阶段:近地停泊轨道运行段、转移轨道的过渡段和进入目标天体的绕飞段。它们各自的运行状态和相应的数学模型有所差别,特别是转移轨道段的运行特征与绕飞段的卫星轨道的典型特征之间的重大差别,在深空探测任务中受到广泛的重视,如平动点利用中的晕(Halo)轨道和引力加速的节能过渡等。然而,就太阳系而言,这些不同轨道之间有一共同的基本性态,那就是都可以用在牛顿万有引力定律制约下的开普勒轨道(或变化的开普勒轨道)来刻画。本文将针对上述不同运行段轨道对应的数学模型、研究方法和结果,结合我们所做的工作进行综述。     

并联贮箱不平衡输出及其解决途径

分析了空间飞行器推进剂贮箱并联设置时产生的不平衡输出问题，从工程角度估计了不平衡输出的程度。对于不允许测量贮箱压降的金属膜片贮箱，在其出口设置气蚀文都利管是解决并联贮箱不平衡输出的简单而又有效的方案。