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251.
The aim of this study was to estimate the acute effects of low dose 12C6+ ions or X-ray radiation on human immune function. The human peripheral blood lymphocytes (HPBL) of seven healthy donors were exposed to 0.05 Gy 12C6+ ions or X-ray radiation and cell responses were measured at 24 h after exposure. The cytotoxic activities of HPBL were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT); the percentages of T and NK cells subsets were detected by flow cytometry; mRNA expression of interleukin (IL)-2, tumor necrosis factor (TNF)-α and interferon (IFN)-γ were examined by real time quantitative RT-PCR (qRT-PCR); and these cytokines protein levels in supernatant of cultured cells were assayed by enzyme-linked immunosorbent assays (ELISA). The results showed that the cytotoxic activity of HPBL, mRNA expression of IL-2, IFN-γ and TNF-α in HPBL and their protein levels in supernatant were significantly increased at 24 h after exposure to 0.05 Gy 12C6+ ions radiation and the effects were stronger than observed for X-ray exposure. However, there was no significant change in the percentage of T and NK cells subsets of HPBL. These results suggested that 0.05 Gy high linear energy transfer (LET) 12C6+ radiation was a more effective approach to host immune enhancement than that of low LET X-ray. We conclude that cytokines production might be used as sensitive indicators of acute response to LDI.  相似文献   
252.
The low background values at nighttime of the mesospheric hydroxyl (OH) radical make it easier to single out the atmospheric response to the external solar forcing in Polar Regions. Because of the short lifetime of HOx, it is possible to follow the trails of Solar Energetic Particle (SEP) events in the terrestrial atmosphere, as shown by Storini and Damiani (2008). The sensitivity of this indicator makes discernible not only extreme particle events with a flux peak of several thousand pfu [1 pfu = 1 particle/(cm2 s sr)] at energies >10 MeV, but also those with lower flux up to about 300 pfu. Using data from the Microwave Limb Sounder (MLS) on board the EOS AURA satellite, we examined the correlation of OH abundance vs. solar proton flux for almost all the identified SEP events spanning from November 2004 to December 2006 (later on no more SEP events occurred during Solar Cycle no. 23). The channels at energies greater than 5 MeV and 10 MeV showed the best correlation values (r ∼ 0.90–0.95) at altitudes around 65–75 km whereas, as expected, the most energetic channels were most highly correlated at lower altitudes. Therefore, it is reasonably possible to estimate the solar proton flux from values of mesospheric OH (and viceversa) and it could be useful in studying periods with gaps in the records of solar particles.  相似文献   
253.
In this paper, Science Operations Planning Expertise (SOPE) is defined as the expertise that is held by people who have the two following qualities. First they have both theoretical and practical experience in operations planning, in general, and in space science operations planning in particular. Second, they can be used, on request and at least, to provide with advice the teams that design and implement science operations systems in order to optimise the performance and productivity of the mission. However, the relevance and use of such SOPE early on during the Mission Design Phase (MDP) is not sufficiently recognised. As a result, science operations planning is often neglected or poorly assessed during the mission definition phases. This can result in mission architectures that are not optimum in terms of cost and scientific returns, particularly for missions that require a significant amount of science operations planning. Consequently, science operations planning difficulties and cost underestimations are often realised only when it is too late to design and implement the most appropriate solutions. In addition, higher costs can potentially reduce both the number of new missions and the chances of existing ones to be extended. Moreover, the quality, and subsequently efficiency, of SOPE can vary greatly. This is why we also believe that the best possible type of SOPE requires a structure similar to the ones of existing bodies of expertise dedicated to the data processing such as the International Planetary Data Alliance (IPDA), the Space Physics Archive Search and Extract (SPASE) or the Planetary Data System (PDS). Indeed, this is the only way of efficiently identifying science operations planning issues and their solutions as well as of keeping track of them in order to apply them to new missions. Therefore, this paper advocates for the need to allocate resources in order to both optimise the use of SOPE early on during the MDP and to perform, at least, a feasibility study of such a more structured SOPE.  相似文献   
254.
轴对称结构RBCC发动机超燃模态试验和数值模拟   总被引:1,自引:0,他引:1  
为研究轴对称结构RBCC发动机超燃模态下的点火和燃烧性能,进行了地面直连试验。采用中心支板火箭与小支板组喷注相结合的方式作为点火和火焰稳定方式,并对燃料喷注方案进行了研究。试验与数值模拟结果表明,采用这种点火方式能实现轴对称结构RBCC发动机的可靠点火和稳定燃烧。二次燃料采取多级喷注的方式能充分利用流道中的氧气,实现较充分的燃烧,但应控制燃料喷注比例。双支板组的加入,能促进燃料与中心空气流的充分掺混,提升燃烧效率,获得较优的燃烧性能。  相似文献   
255.
空间实验室大面积太阳电池阵技术研究   总被引:3,自引:0,他引:3  
介绍了空间实验室大面积太阳电池阵的方案构型,并进行了模态分析、热结构耦合分析和动力学仿真分析。生产出了全尺寸的集成演示样机,进行了展开试验、主展开机构的模态试验,以及半刚性太阳电池板和二自由度驱动机构的振动试验。计算和试验结果表明,技术方案是可行的。  相似文献   
256.
Remote sensing scientists work under assumptions that should not be taken for granted and should, therefore, be challenged. These assumptions include the following:1. Space, especially Low Earth Orbit (LEO), will always be available to governmental and commercial space entities that launch Earth remote sensing missions.2. Space launches are benign with respect to environmental impacts.3. Minimization of Type 1 error, which provides increased confidence in the experimental outcome, is the best way to assess the significance of environmental change.4. Large-area remote sensing investigations, i.e. national, continental, global studies, are best done from space.5. National space missions should trump international, cooperative space missions to ensure national control and distribution of the data products.At best, all of these points are arguable, and in some cases, they're wrong. Development of observational space systems that are compatible with sustainability principles should be a primary concern when Earth remote sensing space systems are envisioned, designed, and launched. The discussion is based on the hypothesis that reducing the environmental impacts of the data acquisition step, which is at the very beginning of the information stream leading to decision and action, will enhance coherence in the information stream and strengthen the capacity of measurement processes to meet their stated functional goal, i.e. sustainable management of Earth resources. We suggest that unconventional points of view should be adopted and when appropriate, remedial measures considered that could help to reduce the environmental footprint of space remote sensing and of Earth observation and monitoring systems in general. This article discusses these five assumptions in the context of sustainable management of Earth's resources. Taking each assumption in turn, we find the following:(1) Space debris may limit access to Low Earth Orbit over the next decades.(2) Relatively speaking, given that they're rare event, space launches may be benign, but study is merited on upper stratospheric and exospheric layers given the chemical activity associated with rocket combustion by-products.(3) Minimization of Type II error should be considered in situations where minimization of Type I error greatly hampers or precludes our ability to correct the environmental condition being studied.(4) In certain situations, airborne collects may be less expensive and more environmentally benign, and comparative studies should be done to determine which path is wisest.(5) International cooperation and data sharing will reduce instrument and launch costs and mission redundancy. Given fiscal concerns of most of the major space agencies – e.g. NASA, ESA, CNES – it seems prudent to combine resources.  相似文献   
257.
为同时兼顾千米量级尺度空间太阳能电站聚光系统的在轨发射安装难度、光学收集效率、稳定性及结构工艺等多方面的因素,提出采用基于球面正多面体的经纬线划分法模块化构建球形聚光器。该方法不仅可实现基础划分单元分布均匀、规格种类少,降低在轨构建与运载发射难度。而且只要合理控制弧高等分数和基础划分单元的口径就可以同时保证聚光系统的光学收集效率。理论与仿真结果显示,当弧高等分数为24时,该划分法共有25种基础单元件,整个球面被分成5762块。并且此时模块化构建的实际球形聚光器的光学收集效率与理想球面相比基本保持不变,解决了太阳能电站聚光系统设计中存在的关键问题。  相似文献   
258.
李献斌  王建  范广腾 《宇航学报》2020,41(5):592-598
为提高低轨指向性信息分发链路的频谱利用效率,从天基分发平台与地面用户的相对位置关系入手,建立了分发指向、编码增益与信道传输容量的量化关系。在此基础上,提出一种低轨天基信息定向分发区域分割编码控制方法,该方法针对不同信息分发区域,采用最小均方误差(MMSE)作为区域分割准则选择编码方式,既提升了信道传输效率也便于工程实现。最后,本文通过仿真分析了方法的效能和性能影响因素,并与现有自适应编码方法进行了对比,验证了本方法的有效性和可靠性。  相似文献   
259.
低轨卫星的轨道寿命主要取决于大气的耗散作用,其轨道在不断变小(即高度降低)变圆的状态下进入地球稠密大气层中陨落。但地球转移轨道(GTO)碎片的运行轨道是一个近地点高度为200km,远地点高度达36000km的大偏心率(e=0.73)椭圆轨道,其轨道寿命主要由第三体(日、月)引力摄动所决定,而且还与其轨道的初始状态有密切关系。本文将根据地球卫星轨道变化规律进行理论分析,阐明力学机制,并给出相应的数值验证。  相似文献   
260.
Small space robots have the potential to revolutionise space exploration by facilitating the on-orbit assembly of infrastructure, in shorter time scales, at reduced costs. Their commercial appeal will be further improved if such a system is also capable of performing on-orbit servicing missions, in line with the current drive to limit space debris and prolong the lifetime of satellites already in orbit. Whilst there have been a limited number of successful demonstrations of technologies capable of these on-orbit operations, the systems remain large and bespoke. The recent surge in small satellite technologies is changing the economics of space and in the near future, downsizing a space robot might become be a viable option with a host of benefits. This industry wide shift means some of the technologies for use with a downsized space robot, such as power and communication subsystems, now exist. However, there are still dynamic and control issues that need to be overcome before a downsized space robot can be capable of undertaking useful missions. This paper first outlines these issues, before analyzing the effect of downsizing a system on its operational capability. Therefore presenting the smallest controllable system such that the benefits of a small space robot can be achieved with current technologies. The sizing of the base spacecraft and manipulator are addressed here. The design presented consists of a 3 link, 6 degrees of freedom robotic manipulator mounted on a 12U form factor satellite. The feasibility of this 12U space robot was evaluated in simulation and the in-depth results presented here support the hypothesis that a small space robot is a viable solution for in-orbit operations.  相似文献   
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