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561.
IntroductionLocomotor and some resistance exercises in space require a gravity replacement force in order to allow 1g-like ground reaction forces to be generated. Currently bungee cords, or other loading devices, interface with the crew member through a harness with a waist belt and shoulder straps. Crew members often find the application of the required loads to be uncomfortable, particularly at the hips.MethodsAn experimental harness was built that differed from previous in-flight designs by having a wider, moldable waist belt and contoured shoulder straps with additional padding. Eight subjects ran at 100% body weight (BW) loading for a total duration of 30 min per day on 12 days over a 3-week period in simulated 0-g conditions using horizontal suspension. A 100 mm Visual Analog Scale (VAS)1 was used to assess harness-related and lower extremity discomfort at the end of each run.ResultsThe overall rating of harness discomfort decreased from 27 mm on the 100 mm scale on day 1 to 10 mm on day 12, with significant decreases recorded for the back and hip regions as well as the overall harness.DiscussionThe experimental harness allows for repeated exposure to 30-minute bouts of 100% BW loaded simulated 0-g running with levels of discomfort less than 30 mm on a VAS scale of 0–100 mm. We believe that the use of such a harness during on-orbit exercise countermeasures may allow exercise to be performed at levels which are more effective in preventing bone and muscle loss. 相似文献
562.
L.F. Hu A.R. Qian Y. Wang S.M. Di P. Shang 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2013
The bone loss induced by microgravity is partly due to the decrease of mature osteoblasts. In the present study, we employed the random positioning machine (RPM) to simulate microgravity and investigated the acute effects of simulated microgravity on the differentiation of 2T3 preosteoblasts. Following 7 days’ culture under normal (1 g) condition, cells were exposed to simulated microgravity for 24 h. The results showed that 24 h treatment of simulated microgravity significantly decreased alkaline phosphatase (ALP) activity without changing the cell morphology. In addition, the mRNA expressions of osteogenic genes, including runt-related gene 2 (Runx2), osterix, osteocalcin (OC), type I collagen (Col I) and bone morphogenetic protein (BMP), were dramatically downregulated. Moreover, western blot analysis of total extracellular signal-regulated kinase (Erk) and phosphorylated Erk (p-Erk) indicated that p-Erk level, which represents the Erk activation status, was increased. Taken together, our results suggested that acute exposure to simulated microgravity inhibited osteoblast differentiation through modulating the expression of osteogenic genes and the Erk activity. These findings provide new insight for bone loss due to microgravity and unloading. 相似文献
563.
In a paper submitted to A&A we present the first line blanketed hydrodynamic models of spherically expanding atmospheres of hot stars. This paper is complementary to the submitted paper. Here, we emphasize the advantages and the weak points of our approach and we present additional technical aspects.The models are characterised by a simultaneous solution of the equation of motion, the non-LTE populations of H and He, and radiation transfer in a line blanketed atmosphere. The entire domain from the optically thick photosphere out to the terminal velocity of the wind is treated. The radiative forces are evaluated consistently with the depth-dependent radiation field, taking into account multiple scattering by metal lines and line overlap. 相似文献
564.
一种被称为液弹的新型技术问世了,它是将液体和弹性元素结合在一起,能提供极好的动态特性来解决直升机振动和阻尼问题的。本文阐述了液弹阻尼器的工作原理,并将液弹阻尼器同粘弹阻尼器和液压阻尼器进行了对比。 相似文献
565.
马勉军%罗崇泰%张德靖%黄良甫 《宇航材料工艺》2006,36(Z1):31-37
简述了DC93-500和GN511硅凝胶材料原子氧环境试验过程,分析和考察了DC93-500和GN511硅凝胶材料在原子氧环境作用下的侵蚀效应,探索了原子氧环境对硅凝胶材料的作用机理.结果表明在原子氧环境作用下,DC93-500和GN511硅凝胶材料样品的可见光透射率明显下降;样品表面被氧化并出现龟裂裂纹和凸起的小岛;随着原子氧作用累积通量的进一步增加,样品表面会由于小岛被剥落而发生质损现象;相对于GN511而言,DC93-500硅凝胶材料在原子氧环境下的结构和性质较为稳定. 相似文献
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在某些特殊工艺的感应加热中,感应线圈需要通过延伸电缆与电源连接.为了解决延伸电缆带来的功率损耗高的问题,分析了并行实芯导体结构、同轴空心导体结构和多束细漆包线密布结构等3种结构形式的电缆的功率损耗和回路电感储能的情况,并进行了试验测定与分析,结果表明,多束细漆包线密布结构电缆上的功率损耗最小,同轴空心导体结构电缆回路的电感量最小.据此,提出了以同轴空心导体结构为基本结构,内、外导体为多束细漆包线密布而成的延伸电缆结构形式. 相似文献
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