Effects of simulated weightlessness on the intestinal mucosal barrier of rats

This study employed a rat tail-suspension model to investigate the effects of simulated weightlessness on the intestinal mucosal barrier. Twenty-four Wistar rats were randomly divided into control (CON), 14-day tail-suspension (SUS-14d), and 21-day tail-suspension (SUS-21d) groups (n = 8 per group). Expression of occludin and zonula occludins-1 (ZO-1), proteins of the tight junction (TJ), in the intestinal mucosa was measured by immunohistochemical analysis, Western blotting, and mRNA fluorescent quantitation PCR. Plasma concentrations of diamine oxidase (DAO) and d-lactate were determined using an enzymatic spectrophotometric assay. Expression of occludin and ZO-1 was reduced in the SUS-14d and SUS-21d groups as compared to the CON group, with lowest expression observed in the SUS-21d group (P < 0.01). Examination by transmission electron microscopy (TEM) of the jejunal epithelium revealed increased intercellular space, decreased TJ and desmosome densities, and destruction of microvilli in the SUS-14d and SUS-21d groups. Plasma DAO and d-lactate concentrations in the SUS-21d group were higher than those in SUS-14d group and significantly higher than those in the CON group (P < 0.01). In all three groups, the expression of occludin and ZO-1 was found to correlate negatively with DAO (P < 0.01) and d-lactate (P < 0.01) concentrations. It is concluded that simulated weightless results in down-regulation of expression of TJ proteins in the rat intestinal mucosa. Simulated weightlessness is proposed to increase intestinal permeability through damage to the TJ.     

Debris Discs Around Stars: The 2004 ISO Legacy

Debris discs around stars were first discovered by the Infrared Astronomical Satellite (IRAS) in 1983. For the first time material orbiting another star than the Sun, but distinct from a circumstellar envelope, was observed through its far infrared emission. This major discovery motivated astronomers to investigate those discs by further analyzing the IRAS data, using ground-based telescopes for the hunting of exoplanets, developing several projects using the Infrared Space Observatory (ISO), and now exploiting the ISO Data Archive (IDA). This review presents the main ISO results, statistical as well as individual, on debris discs in orbit around pre-main-sequence and main-sequence stars. Based on observations with ISO, an ESA project with instruments funded by ESA Member States (especially the PI countries: France, Germany, The Netherlands, and the United Kingdom), and with the participation of ISAS and NASA.     

PWM型半桥式开关稳压电源的设计

介绍了一款基于PWM技术的半桥式开关稳压电源.给出了高频变压器、PWM控制及驱动电路的详细设计方法.用该方法设计了一台功率为150 W、输出电压为 15 V的半桥式开关稳压电源,并给出了实验波形.     

Thermoelectric Properties of Mg2Si1-xSnx Synthesized by Bulk Mechanical Alloying

Bulk mechanical alloying （BMA） has been successfully applied to solid-state synthesis of p-type and n-type thermoelectric materials Mg2Si1-xSnx （x = 0, 0.2, 0.4, 0.6, 0.8, 1） from element-powders at the room temperature in a relatively short time. The electrical conductivity, the Seebeck coefficient and the thermal conductivity of the Mg2Si1-xSnx are quite sensitive to the x-content. With the x-content rising, the electrical conductivity increases. When x = 0.6, it reaches the lowest and Mg2Si shows an n-type of semi-conducting However, when x = 0.2 and T 〉525 K, the Seebeck coefficient of the samples will change the opposite way. While x≥0.4, the samples present a p-type of semi-conducting. The figure of merit, Z of Mg2Si1-xSnx will be obtained in the range from 300 K to 700 K. When x = 0.6, Z proves to be higher than that of other samples at 300 K≤ T≤650 K.     

提高飞机使用可用度的途径

飞机的使用可用度是与飞机战备完好性相关的重要参数,本文研究了提高飞机使用可用度的途 径,并提出了飞机可用度最低门限值的概念     

CBERS-1卫星红外多光谱扫描仪主光学装置设计

文章介绍了CBERS -1卫星IRMSS主光学装置的设计 ,叙述了光学系统和结构选择、装配调试、像质的稳定性、可靠性问题。该装置在焦面Φ8mm范围内弥散园优于Φ0.010mm ,调制传递函数MTF优于0.91。     

两种信道编码记录方式在光盘应用中的对比

依据数字编码理论对几种光盘编码调制的结构参数性能进行了比较，着重分析了光盘的两种信道编码记录方式：用于磁光（ＭａｇｎｅｔｏＯｐｔｉｃａｌｄｉｓｋ－ＭＯ）光盘的游程长度受限（ＲｕｎＬｅｎｇｔｈＬｉｍｉｍｔｅｄ）脉宽调制（ＰｕｌｓｅＷｉｄｔｈＭｏｄｕｌａｔｉｏｎ）［ＲＬＬ（１，７）－ＰＷＭ］记录方式，及用于相变（ＰｈａｓｅＣｈａｎｇｅ－ＰＣ）光盘的游程长度受限（ＲｕｎＬｅｎｇｔｈＬｉｍｉｍｔｅｄ）脉位调制（ＰｕｌｓｅＰｏｓｉｔｉｏｎＭｏｄｕｌａｔｉｏｎ）［ＲＬＬ（２，７）－ＰＰＭ］记录方式，并结合记录介质的特点，阐明了两者并存的原因．     

基于DTW的HJ-1B卫星地表温度产品质量检验

HJ-1B卫星热红外数据应用广泛,但其地表温度反演产品的质量检验工作尚不完善。以黑河流域为研究区,利用普适性单通道算法得到HJ 1B地表温度,基于7个地面站点（下垫面为荒漠、沙漠、植被、农作物、雪地和湿地）同步观测资料和MODIS地表温度产品（MOD11A1）,引入动态时间规整方法（DTW）对站点处HJ 1B地表温度进行验证。试验结果表明：HJ 1B地表温度反演产品与地面观测值的偏差值在沙漠和荒漠站点为1K以内,均方根误差在05K左右;对于植被和农作物站点的偏差在2K以内,均方根误差为1~2K;基于DTW的验证对时序不匹配的数据评价结果与现有指标表现一致。HJ-1B地表温度反演产品与地面站点的相对偏差均低于其与MODIS地表温度反演产品的相对偏差。     

嫦娥一号卫星热设计及计算分析

嫦娥一号卫星整星主结构以东方红三号卫星平台为基础。由于其复杂的飞行阶段和飞行姿态、以及月球表面特殊的温度分布,卫星表面的外热流非常复杂、变化剧烈,给整星的热控设计带来很大困难,使得整星的热控方案与东方红三号卫星有很大不同。文章着重分析了卫星的特点,并且给出了主要的热控设计方案,最后给出了整星的热分析模型,并对计算结果进行了分析。分析结果表明目前的设计方案满足了卫星在各种工况下的温度指标,实现了总体提出的热控要求。     

“嫦娥一号”卫星观测近月太阳风离子特征

"嫦娥一号"卫星的太阳风离子探测器(SWIDs)的科学目标是研究太阳风与月球的相互作用以及相应的近月空间等离子体环境。文章利用"嫦娥一号"卫星SWIDs探测器在2007年12月30日的观测数据对近月太阳风等离子体环境,包括向阳侧太阳风离子、"拾起"离子以及在月球尾迹边界处的太阳风离子的特征进行分析,得到以下主要观测结果:1)在慢速太阳风中观测到双峰结构,分别为太阳风中的氢离子和二价氦离子;2)在行星际磁场具有明显昏向(+By)分量期间,在月球向阳侧持续观测到有月表散射或反射后被拾起的太阳风离子;3)与入射的太阳风离子不同,这些拾起的太阳风离子具有明显的角度分布特征;4)在行星际磁场昏向(晨向)期间,太阳风中的氢离子在月球尾迹北半球的边界处呈现减速(加速)特征并进入尾迹;而并未发现氦离子进入尾迹的特征。"嫦娥一号"卫星的这些观测数据对于认识近月空间等离子体环境有着重要的意义。