Early effects of low dose C ion or X-ray irradiation on human peripheral blood lymphocytes

The aim of this study was to estimate the acute effects of low dose ¹²C⁶⁺ ions or X-ray radiation on human immune function. The human peripheral blood lymphocytes (HPBL) of seven healthy donors were exposed to 0.05 Gy ¹²C⁶⁺ ions or X-ray radiation and cell responses were measured at 24 h after exposure. The cytotoxic activities of HPBL were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT); the percentages of T and NK cells subsets were detected by flow cytometry; mRNA expression of interleukin (IL)-2, tumor necrosis factor (TNF)-α and interferon (IFN)-γ were examined by real time quantitative RT-PCR (qRT-PCR); and these cytokines protein levels in supernatant of cultured cells were assayed by enzyme-linked immunosorbent assays (ELISA). The results showed that the cytotoxic activity of HPBL, mRNA expression of IL-2, IFN-γ and TNF-α in HPBL and their protein levels in supernatant were significantly increased at 24 h after exposure to 0.05 Gy ¹²C⁶⁺ ions radiation and the effects were stronger than observed for X-ray exposure. However, there was no significant change in the percentage of T and NK cells subsets of HPBL. These results suggested that 0.05 Gy high linear energy transfer (LET) ¹²C⁶⁺ radiation was a more effective approach to host immune enhancement than that of low LET X-ray. We conclude that cytokines production might be used as sensitive indicators of acute response to LDI.     

基于Probit模型的航空差旅管理市场分析

研究分析企业和差旅管理公司的哪些因素会对差旅管理业务的选择产生影响,帮助差旅管理公司明确企业的差旅管理偏好,从而推动中国航空差旅管理市场的发展.针对航空差旅管理市场的现状,在对50家企业进行问卷调查后,通过Probit模型得出10个因素对企业选择差旅管理业务的影响程度,其中“现金流量”、“资金结算手段”、“增值服务种类”和“政策与系统的匹配度”4个因素具有显著性.最后,根据实证结果对企业和差旅管理公司提出相应的建议.     

利用地月间空间站的载人登月飞行模式分析

为提高空间站利用率,降低载人登月任务成本,有效开发地月空间,研究了基于地月空间不同轨道空间站的载人登月飞行模式。首先对比直接往返登月飞行模式,对基于空间站的载人登月飞行模式进行任务分析,通过空间站将载人登月任务解耦为载人天地往返任务和登月任务两部分;其次通过轨道设计和稳定性分析提出考虑登月任务需求的地月间空间站可运行轨道和停泊点;最后建立一套飞行模式评价模型,从速度增量需求、飞行时间、空间环境、登月任务窗口、测控条件、交会对接技术难度、后续任务支持性和任务可靠性方面对6种不同位置空间站的登月飞行模式进行分析和定量评价。评价结果表明基于L2点Halo轨道空间站的载人登月飞行模式为更优飞行模式。     

基于人因分析的可靠性管理研究和实践

以人因研究为基础,提出安全性工作与经济性工作结合、质量管理工作与工程管理工作结合、技术管理工作与绩效管理工作结合的观点,旨在寻求一条能使生产单位直接获益的可靠性管理新思路,并由此探索将总部与基地的可靠性管理工作紧密结合的新途径。     

高转速风扇叶片外物撞击损伤的定量评价方法

外物撞击是造成航空发动机风扇叶片变形、损伤甚至断裂的主要因素。针对外物撞击持续时间短、瞬间载荷大、损伤影 响因素多，难以进行定量损伤评价的问题，提出基于叶片损伤参数α的叶片损伤定量评价方法。以发动机风扇叶片受冰撞为例， 采用非接触叶尖计时测量方法，对叶片撞击产生的叶尖位移进行监测分析，验证了该方法的可行性。采用瞬态动力学分析方法对 叶片经受撞击过程进行全流程仿真模拟，并采用正交试验法定量研究了外物撞击过程中的撞击速度、叶片转速、撞击位置3种因 素对叶片损伤参数α的影响，拟合回归方程并绘制了这3种因素的3D响应曲面图，得到各因素的影响权重。结果表明：冰块速度 与撞击位置同时下降时，叶片损伤弱化效果显著。该方法可为大型风扇叶片抗外物打击性能设计和在役健康监测提供理论支撑。     

Crew autonomy for deep space exploration: Lessons from the Antarctic Search for Meteorites

Future piloted missions to explore asteroids, Mars, and other targets beyond the Moon will experience strict limitations on communication between vehicles in space and control centers on Earth. These limitations will require crews to operate with greater autonomy than any past space mission has demonstrated. The Antarctic Search for Meteorites (ANSMET) project, which regularly sends small teams of researchers to remote parts of the southern continent, resembles a space mission in many ways but does not rely upon a control center. It provides a useful crew autonomy model for planners of future deep space exploration missions. In contrast to current space missions, ANSMET gives the crew the authority to adjust competing work priorities, task assignments, and daily schedules; allows the crew to be the primary monitor of mission progress; demands greater crew accountability for operational errors; requires the crew to make the most of limited communication bandwidth; adopts systems designed for simple operation and failure recovery; and grants the crew a leading role in the selection and stowage of their equipment.     

浅谈影响大学外语听力教学的因素及其提高途径

听力教学是语言教学的重要组成部分，听力水平的提高受到多种因素的影响与制约。如何利用积极有利的因素，克服消极不利的因素，采取行之有效的方法提高学生的听力水平，对整个的外语教学起着十分重要的作用。     

Pilots for space tourism

This article sheds light on the key player needed for any space tourism adventure: the pilot who flies the spacecraft. The paper addresses the potential benefits of including a pilot at the controls when designing a space tourism spacecraft. It examines the basic qualifications and advanced skills required of space tourism pilots and discusses key training requirements for selected pilots and space pilots' pay and benefits. In addition, the research concludes that, just as the pioneers of passenger transport in aviation entertained and captured the interest of their passengers, the space pilot should have the skills of a tour guide.     

Materials selection for electronic enclosures in space environment considering electromagnetic interference effect

Using low power electronic devices for space applications to reduce the mass and energy consumption has lead to electromagnetic interference (EMI) problem. Electronic enclosures are used to shield electronic devices against EMI. In the past, electromagnetic shielding has been mainly the only criteria considered in electronic enclosure design. However, there are several structural and thermal requirements for selection of shielding materials which should also be taken into account. In this research work, three quantitative materials selection methods, i.e. Digital Logic (DL), Modified Digital Logic (MDL), and Z-transformation, are employed to select the best material from among a list of candidate materials. Composite and metallic electronic enclosures are explored and the best material is selected. Z-transformation method is applicable to both of the considered case studies while DL and MDL can only be used for solving one of them. Z-transformation method ranks aluminum as the first choice among various metallic materials. The wide range of Z-transformation application and its practical results confirm the superiority of Z-transformation method over DL and MDL methods.     

Assessing the feasibility of involving gaseous products resulting from physicochemical oxidation of human liquid and solid wastes in the cycling of a bio-technical life support system

The study addresses the possible ways of involving gaseous products produced by “wet” incineration of human wastes mixed with H₂O₂ in an alternating electric field in the cycling of the physical model of a bio-technical life support system (BTLSS). The resulting gas mixture contains CO₂ and O₂, which are easily involved in the cycling in the closed ecosystem, and NH₃, which is unacceptable in the atmosphere of the BTLSS. NH₃ fixation has been proposed, which is followed by nitrification and involvement of the resulting products in the mass exchange of the closed system. Experiments have been performed to show that plants can be grown in the atmosphere resulting from the closing of the gas loop that includes a physicochemical installation and a growth chamber with plants representing the phototrophic compartment of the BTLSS. The results of the study suggest the conclusion that the proposed method of organic waste oxidation can be a useful tool in creating a physical model of a closed-loop integrated BTLSS.