某型惯性导航系统典型53#故障的排除及解析

某型惯性导航系统在飞机上时有故障发生,造成导航系统无法正常使用,其中较为突出的是惯导报53#环境温控故障.为降低该惯导在飞机上的故障率,通过研究环境温控回路的工作原理,解析其故障机理,并以几起典型53#故障的排除为例深入分析,提出有效的预防措施,以延伸修理深度,提高产品修理质量.     

3J53弹簧表面裂纹缺陷原因分析

3J53钢丝在车间缠绕成弹簧并经热处理后发现其表面存在线性缺陷。用扫描电镜对钢丝线性缺陷的形貌进行了分析,对线性缺陷区域进行了能谱分析,并利用金相显微镜观察了线性缺陷的中心部位及其周围区域的金相组织。结果表明:钢丝表面的线性缺陷呈锯齿状,沿钢丝轴向方向,为裂纹型折叠缺陷。折叠缺陷是钢丝在生产过程中形成,在绕簧和热处理过程中,裂纹型折叠缺陷发生扩展和延伸,最终形成线性缺陷。     

MMC在电网质量监测海量数据存储中的应用研究

针对长时间电压参数监测中海量数据存储问题,提出了移植数码设备中大容量通用数码卡的存储思路,论述了MMC卡的基本结构和工作原理,设计了AT89S53与MMC卡的接口电路和系统软件,阐述了基于MMC自定义文件系统的数据存储实现软件,有效解决了问题。     

Expression of p53-regulated genes in human cultured lymphoblastoid TSCE5 and WTK1 cell lines after spaceflight in a frozen state

The 53 kDa tumor suppressor protein p53 is generally thought to contribute to the genetic stability of cells and to protect cells from DNA damage through the activity of p53-centered signal transduction pathways. To clarify the effect of space radiation on the expression of p53-dependent regulated genes, gene expression profiles were compared between two human cultured lymphoblastoid cell lines: one line (TSCE5) has a wild-type p53 gene status, and the other line (WTK1) has a mutated p53 gene status. Frozen human lymphoblastoid cells were stored in a freezer in the International Space Station (ISS) for 133 days. Gene expression was analyzed using DNA chips after culturing the space samples for 6 h on the ground after their return from space. Ground control samples were also cultured for 6 h after being stored in a frozen state on the ground for the same time period that the frozen cells were in space. p53-Dependent gene expression was calculated from the ratio of the gene expression values in wild-type p53 cells and in mutated p53 cells. The expression of 50 p53-dependent genes was up-regulated, and the expression of 94 p53-dependent genes was down-regulated after spaceflight. These expression data identified genes which could be useful in advancing studies in basic space radiation biology. The biological meaning of these results is discussed from the aspect of gene functions in the up- and down-regulated genes after exposure to low doses of space radiation.     

A low dose pre-irradiation induces radio- and heat-resistance via HDM2 and NO radicals,and is associated with p53 functioning

The aim of this work was to clarify the effect of low dose pre-irradiation on radio- and heat-sensitivity. Wild-type (wt) p53 and mutated (m) p53 cells derived from the human lung cancer H1299 cell line were used. The parental H1299 cell line is p53-null. Cellular sensitivities were determined with a colony-forming assay. When wtp53 cells were exposed to a low dose X-irradiation, induction of radio- and heat-resistance was observed only in the absence of RITA (an inhibitor of p53-HDM2 interactions), aminoguanidine (an iNOS inhibitor) and c-PTIO (an NO radical scavenger). In contrast, the induced radio- and heat-resistance was not observed under similar conditions in mp53 cells. Moreover, heat-resistance as well as radio-resistance developed when wtp53 cells were treated with ISDN (an NO generating agent) alone. These findings suggest that NO radicals are an initiator of radio- and heat-resistance, and function through the activation of HDM2 and the depression of p53 accumulation.     

星载二氧化碳探测研究进展

二氧化碳(CO2)是大气中最典型的温室气体，大气中CO2浓度持续增加是全球气温升高的主要原因。温度升高导致自然环境恶劣，各类自然灾害频发，极端天气数量增加，对人类生活环境造成巨大的影响，因此推动绿色低碳发展势在必行。准确监测CO2的排放，了解CO2源和汇的分布，是遏制大气CO2浓度升高、减缓全球变暖的前提条件。因此，准确获取全球范围内高精度时空分辨率的CO2观测数据十分必要。卫星遥感可以有效观测CO2的全球分布，获取大范围高精度数据。本文旨在对目前用于大气CO2探测的卫星载荷发展状况进行综述，包括基于被动遥感CO2的卫星现状和数据产品、基于主动遥感CO2的卫星的研制情况和目前的主要工作进展。     

大气探测激光雷达校飞样机研制与飞行验证

星载激光雷达是高精度测量全球温室气体和气溶胶垂直廓线的重要手段，大气环境监测卫星大气探测激光雷达(ACDL)在国际首次采用激光积分路径差分吸收技术测量全球CO2柱浓度，采用532 nm高光谱探测技术测量气溶胶和云的廓线。星载激光雷达载荷研制期间，同步研制一套主要功能一致的机载大气探测激光雷达校飞样机，并开展机载飞行试验，获取了大量飞行试验及其对比数据，提供了机载平台真实的数据源，对于优化ACDL激光雷达系统参数和研究星载数据反演算法至关重要。最后在机载飞行平台下，验证了优于1 ppm的CO2柱浓度测量精度和优于15%的气溶胶测量精度。未来利用该机载样机可以进一步开展星地对比验证。