Retinal photoreceptor and related gene expression in normal and clinostat-treated fish embryos

Medaka fish had performed mating behavior successfully in space for the first time among vertebrate, and the eggs which were laid in space developed normally, and hatched during the space travel of 15 days aboard the space shuttle in the second International Microgravity Laboratory (IML-2) mission in 1994 (Ijiri 1994). But there has been few studies whether microgravity affects the development of rather complex tissues in this fish. Investigating this problem, we focused on the organogenetic events in the retina in developing Medaka under normal and simulated microgravity conditions (by a three-dimensional clinostat, 3D-clinostat). Our results showed that both normal and 3D-clinostat-treated Medaka embryos developed on almost equal time course. Moreover, we investigated the development of the retina in normal and 3D-clinostat-treated embryos, but there were no differences in organogenesis of their retina. Lamination of retina occurred almost at equal timing and the expressions of opsin genes in the 3D-clinostat-treated group also began almost at the same time as control. Our observations suggest that there were no definite effects of simulated microgravity on the organizations of a complex tissue such as retina in developing fish embryos.     

恒幅及飞行模拟载荷下厚度对裂纹增长的影响

不同厚度试样的疲劳裂纹扩展试验及断口微观分析表明,恒幅加载低应力比飞行模拟载荷条件下具有明显的厚度影响。考查了模型对厚度影响的预测能力。Newman的模型具有预测厚度影响的潜力,广义改进的wellenborg模型不含有厚度影响的考虑,即使通过调整约束系数α的方法也不能计及厚度的影响。厚度对裂纹增长影响的物理原因及模型化有待于进一步研究。     

Tracking considerations in selection of radar waveform for rangeand range-rate measurements

The conventional approach for tracking system design is to treat the detection and tracking subsystems as completely independent units. However, the two subsystems can be designed jointly to improve system (tracking) performance. It is known that different radar signal waveforms result in very different resolution cell shapes (for example, a rectangle versus an eccentric parallelogram) in the range/range-rate space, and that there are corresponding differences in overall tracking performance. We develop a framework for the analysis of this performance. An imperfect detection process, false alarms, target dynamics, and the matched filter sampling grid are all accounted for, using the Markov chain approach of Li and Bar-Shalom. The role of the grid is stressed, and it is seen that the measurement-extraction process from contiguous radar "hits" is very important. A number of conclusions are given, perhaps the most interesting of which is the corroboration in the new measurement space of Fitzgerald's result for delay-only (i.e., range) measurements, that a linear FM upsweep offers very good tracking performance     

The ozonesonde intercomparison experiment at Thumba

An Indo-Soviet collaborative experiment on Ozonesonde Intercomparison was conducted at TERLS in March 1983. Thirteen rocket ozonesondes, eleven balloon ozonesondes and seven meteorological rockets were launched from Thumba. The rocket and balloon soundings were supported by on site Dobson spectrophotometric observations, surface ozone measurements as well as measurements with a Volz type filter photometer. The programme has yielded data on ozone vertical profiles from eleven rocketsondes, seven balloon-sondes and four sets of Umkehr observations. The data is studied with a view to intercompare the various sensors.     

Intramuscular calcium movements: experiments from the Soviet biosatellite Biocosmos.

Experiments have been performed in skeletal muscle fibres from the lateral head of gastrocnemius muscle of female rats. Changes in intramuscular calcium movements due to microgravity conditions have been tested by tension measurements in chemically skinned muscle fibres. Our results show that microgravity induces i) a decrease in maximal muscle strength developed by contractile proteins ii) a decrease of intensity and rate of both Ca release and Ca uptake by the sarcoplasmic reticulum.     

Biological degradation and composition of inedible sweetpotato biomass.

Many challenges are presented by biological degradation in a bioregenerative Controlled Ecological Life Support System (CELSS) as envisioned by the U.S. National Aeronautics and Space Administration (NASA). In the studies conducted with biodegradative microorganism indigenous to sweetpotato fields, it was determined that a particle size of 75 microns and incubation temperature of 30 degrees C were optimal for degradation. The composition of the inedible biomass and characterization of plant nutrient solution indicated the presence of potential energy sources to drive microbial transformations of plant waste. Selected indigenous soil isolates with ligno-cellulolytic or sulfate-reducing ability were utilized in biological studies and demonstrated diversity in ability to reduce sulfate in solution and to utilize alternative carbon sources: a lignin analog--4-hydroxy, 3-methoxy cinnamic acid, cellulose, arabinose, glucose, sucrose, mannitol, galactose, ascorbic acid.     

Material recycling in a regenerative life support system for space use: its issues and waste processing.

First, sources of wastes produced in future human activities in space will be discussed. The quantity and quality of each source will be evaluated. Secondly, water quality requirements for human safety will be shown. Then, techniques to be used for processing and/or recycling the wastes to attain the requirements will be listed. Specific characteristics and limitations of each will be explained. Last, examples of system configurations of the techniques will be shown. The material balances will also be calculated. The issues to be solved will be made clear.     

Human factor in manned Mars mission.

This paper presents the set of specific problems in manned Mars mission, connected with human factor, and scientific approaches for their resolution. The concept of multifunctional medical Complex for Martian spacecraft is discussed.     

The dose rate observed on 19-21 October 1989 and its modulation by geophysical effects.

The Liulin dosimeter-radiometer on the MIR space station detected the 19 October 1989 high energy solar proton event. These results show that the main particle increase contains protons with energies up to about 9 GeV. After the main particle onset the Liulin dosimeter observed a typical geomagnetic cutoff modulation of the dose rate from the solar particles as the MIR space station traversed magnetic latitudes. When the interplanetary shock and associated solar plasma enveloped the earth on 20 October between 14 and 17 UT the radiation exposure increased significantly due to the lowering of the geomagnetic cutoff. The analysis of this event shows how various geophysical phenomena can significantly modulate the dose rate encountered by earth-orbiting spacecraft.     

Evaluating and optimizing horticultural regimes in space plant growth facilities.

In designing innovative space plant growth facilities (SPGF) for long duration space flight, various limitations must be addressed including onboard resources: volume, energy consumption, heat transfer and crew labor expenditure. The required accuracy in evaluating on board resources by using the equivalent mass methodology and applying it to the design of such facilities is not precise. This is due to the uncertainty of the structure and not completely understanding the properties of all associated hardware, including the technology in these systems. We present a simple criteria of optimization for horticultural regimes in SPGF: Qmax = max [M x (EBI)2/(V x E x T], where M is the crop harvest in terms of total dry biomass in the plant growth system; EBI is the edible biomass index (harvest index), V is volume occupied by the crop; E is the crop light energy supply during growth; T is the crop growth duration. The criterion reflects directly on the consumption of onboard resources for crop production.