Do heavy ions cause microlesions in cell membranes?

Heavy ions are a hazard in manned deep space missions. It has been theoretically postulated that when they interact with cells, localized damage in the forms of \"microlesions\" may occur. Purported morphological evidence of these lesions, however, has not been confirmed in the most extensively studied tissue so far, the cornea. Recent morphological evidence from rat corneas demonstrated that holes in membranes do not form as consequence of heavy ion irradiation. This does not mean, however, that some other form of damage is excluded. For example such damage may be physiological in nature, impairing the ability of cells or tissues to function properly. In order to uncover any physiological effects, we investigated the microlesion question by monitoring the electrical potential difference across the endothelium of rat corneas in vitro before, during, and after irradiation. When the corneas were exposed to 1 Gy of 56Fe ions (450 and 600 MeV/a.m.u.), we detected no effect on this parameter. These results suggest that direct physical damage to cell membranes, as predicted by the microlesion theory, does not take place.     

Investigation of helicopter maneuverability by the power balance method

The algorithms for calculating available overloads and maneuvers are presented. Nesterov’s loop maneuver is analyzed.     

A self-normalizing gradient search adaptive array algorithm

A method is described to normalize the step parameter and perturbation amount used for gradient search adaptive algorithms. The step normalization assures rapid stable convergence. The perturbation normalization also assures rapid stable convergence and limits the output perturbation noise to a level below thermal noise. The normalizations are computationally simple and are consistent with the use of a single receiver at the adaptive array output. Results are presented to verify the robustness of the technique.<>     

The effect of the longitudinal propagating waves on the electron acceleration in the reconnecting current sheet

Based upon the most efficient electron acceleration near the midplane of 3D non-neutral driven reconnecting current sheet (RCS) and the electrostatic wave excitation by the drift Maxwellian distribution of electrons in Vlasov simulation, we assume that the electrostatic waves mainly propagate opposite to the reconnecting electric field and investigated how these waves affect the electron acceleration. The main results are: (1) when the electron’s velocity equals to the phase speed of the waves, they will be trapped and have the different accelerating characteristics from the untrapped electrons through solving the momentum equations of electrons analytically; (2) the test particle simulations further prove that the number of the energetic electrons decreases with the increasing intensity of unstable waves, and the distribution of the energetic electrons takes on the double power-law.     

Did life begin on the beach?

Water is one of the prerequisites of life. Further requirements are the existence of a system of interacting organic molecules capable of capturing and converting the supply of external energy and elaborating the replicating function that is needed for propagation. None of this would be possible without the existence of some means of concentrating, selecting, and then containing these mutually interacting substances in proximity to one another, i.e., a primitive cell. Starting from this hypothesis we propose a model for the development of life on Earth. Our model embodies the following new features: (1) rapid cycles of catalysis and transport of material, (2) desegregation (separation by tidal action and degradation by catalysis) as well as segregation (by chromatography on tidal beaches), (3) cross-catalysis instead of auto-catalysis, as well as (4) compartmentalization, although the latter idea is of course not new. But our "lipid first" model, in contrast to earlier "peptide first" or "RNA first" models, provides for the compartments needed to act as a cradle for the subsequent development of information- rich molecules like peptides and RNA. If anything, the earliest information-rich molecules were probably membrane-spanning peptides/proteins.