Onboard Pilot and Remote Copilot for Aviation Safety, Security & Cost Reduction

The 21^st Century Aviation System can reduce the cost of flying, while substantially increasing the safety and security of cargo and carrier aircraft with an onboard pilot/s and a remote copilot residing in a secure ground-based simulator.     

A technique of analyzing critical forces and moments for isotropic rods of arbitrary cross-section in the general case of their complex resistance

The derivation of parametric equations for a limiting surface in the space of internal forces and moments that act in the rod cross-sections, using the basic concepts of plasticity theory and conventional hypotheses of the rod theory, is presented. The plastic properties of rod material are described by the Mises criterion. A case of small displacements and strains under static simple loading is considered. The results of solving a number of problems of constructing limiting curves in the planes of internal forces and moments are given.     

A capillary-driven root module for plant growth in microgravity.

A new capillary-driven root module design for growing plants in microgravity was developed which requires minimal external control. Unlike existing systems, the water supply to the capillary-driven system is passive and relies on root uptake and media properties to develop driving gradients which operate a suction-induced flow control valve. A collapsible reservoir supplies water to the porous membrane which functions to maintain hydraulic continuity. Sheet and tubular membranes consisting of nylon, polyester and sintered porous stainless steel were tested. While finer pore sized membranes allow greater range of operation, they also reduce liquid flux thereby constraining system efficiency. Membrane selection should consider both the maximum anticipated liquid uptake rate and maximum operating matric head (suction) of the system. Matching growth media water retention characteristics to the porous membrane characteristics is essential for supplying adequate liquid flux and gas exchange. A minimum of 10% air-filled porosity (AFP) was necessary for adequate aeration. The capillary-driven module maintained hydraulic continuity and proper gas exchange rates for more than 80 days in a plant growth experiment.     

Optical communication systems for avionics

Avionic information processing and transmission requirements are increasing geometrically, with no end in sight, The only feasible way to meet them is to incorporate fiber-optic communication systems into avionic platforms, Such systems can be employed to replace standard electronic components, to augment existing systems, or to enable new technologies. In this paper, we survey the field of low-power communication systems from the avionics engineering perspective. We review the fundamental merits of optical fiber for information transmission and discuss various information modulation schemes. These modulation techniques determine the performance requirements for laser transmitters, We describe the horizontal- and vertical-cavity semiconductor lasers currently available for these systems, and measure their performance against the additional environmental constraints of avionics platforms. Finally, we outline expected near- and far-term trends in system and device development     

Biodosimetry of heavyions by interphase chromosome painting

We report measurements of chromosomal aberrations in peripheral blood lymphocytes from cancer patients undergoingradiotherapy treatment. Patients with cervix or esophageal cancer were treated with 10 MV X-rays produced at a LINAC accelerator, or high-energy carbon ions produced at the HIMAC accelerator at the National Institute for Radiological Sciences (NIRS) in Chiba. Blood samples were obtained before, during, and after the radiation treatment. Chromosomes were prematurely condensed by incubation in calyculin A. Aberrations in chromosomes 2 and 4 were scored after fluorescence in situ hybridization with whole-chromosome probes. Pre-treatment samples were exposed in vitro to X-rays, individual dose-response curves for the induction of chromosomal aberrations were determined, and used as calibration curves to calculate the effective whole-body dose absorbed during the treatment. This calculated dose, based on the calibration curve relative to the induction of reciprocal exchanges, has a sharp increase after the first few fractions of the treatment, then saturates at high doses. Although carbon ions are 2–3 times more effective than X-rays in tumor sterilization, the effective dose was similar to that of X-ray treatment. However, the frequency of complex-type chromosomal exchanges was much higher for patients treated with carbon ions than X-ray.     

Evolution of galaxy cluster scaling from XMM-Newton observation of the galaxy clusters at z ⩾ 0.4

We present here new XMM-Newton observations of 3 relatively cool clusters at z ≈ 0.4, complemented by archival observations of 3 other clusters at similar redshift. We derived the M–T and R–T relations from the hydrostatic equation using an isothermal temperature distribution.     

Solar flare forecasting model supported with artificial neural network techniques

Nowadays operational models for solar activity forecasting are still based on the statistical relationship between solar activity and solar magnetic field evolution. In order to set up this relationship, many parameters have been proposed to be the measures. Conventional measures are based on the sunspot group classification which provides limited information from sunspots. For this reason, new measures based on solar magnetic field observations are proposed and a solar flare forecasting model supported with an artificial neural network is introduced. This model is equivalent to a person with a long period of solar flare forecasting experience.     

Simultaneous measurement of multiple radiation-induced protein expression profiles using the Luminex(TM) system.

Space flight results in the exposure of astronauts to a mixed field of radiation composed of energetic particles of varying energies, and biological indicators of space radiation exposure provides a better understanding of the associated long-term health risks. Current methods of biodosimetry have employed the use of cytogenetic analysis for biodosimetry, and more recently the advent of technological progression has led to advanced research in the use of genomic and proteomic expression profiling to simultaneously assess biomarkers of radiation exposure. We describe here the technical advantages of the Luminex(TM) 100 system relative to traditional methods and its potential as a tool to simultaneously profile multiple proteins induced by ionizing radiation. The development of such a bioassay would provide more relevant post-translational dynamics of stress response and will impart important implications in the advancement of space and other radiation contact monitoring.     

Track segment association, fine-step IMM and initialization with Doppler for improved track performance

In this work we present a new track segment association technique to improve track continuity in large-scale target tracking problems where track breakages are common. A representative airborne early warning (AEW) system scenario, which is a challenging environment due to highly maneuvering targets, close target formations, large measurement errors, long sampling intervals, and low detection probabilities, provides the motivation for the new technique. Previously, a tracker using the interacting multiple model (IMM) estimator combined with an assignment algorithm was shown to be more reliable than a conventional Kalman filter based approach in tracking similar targets but it still yielded track breakages due to the difficult environment. In order to combine the broken track segments and improve track continuity, a new track segment association algorithm using a discrete optimization approach is presented. Simulation results show that track segment association yields significant improvements in mean track life as well as in position, speed, and course rms errors. Also presented is a modified one-point initialization technique with range rate measurements, which are typically ignored by other initialization techniques, and a fine-step IMM estimator, which improves performance in the presence of long revisit intervals. Another aspect that is investigated is the benefit of "deep" (multiframe or N-dimensional, with N > 2) association, which is shown to yield significant benefit in reducing the number of false tracks.     

Genomic instability and tumorigenic induction in immortalized human bronchial epithelial cells by heavy ions

Carcinogenesis is postulated to be a progressive multistage process characterized by an increase in genomic instability and clonal selection with each mutational event endowing a selective growth advantage. Genomic instability as manifested by the amplification of specific gene fragments is common among tumor and transformed cells. In the present study, immortalized human bronchial (BEP2D) cells were irradiated with graded doses of either 1GeV/nucleon ⁵⁶Fe ions or 150 keV/μm alpha particles. Transformed cells developed through a series of successive steps before becoming tumorigenic in nude mice. Tumorigenic cells showed neither ras mutations nor deletion in the p16 tumor suppressor gene. In contrast, they harbored mutations in the p53 gene and over-expressed cyclin D1. Genomic instability among transformed cells at various stage of the carcinogenic process was examined based on frequencies of PALA resistance. Incidence of genomic instability was highest among established tumor cell lines relative to transformed, non-tumorigenic and control cell lines. Treatment of BEP2D cells with a 4 mM dose of the aminothiol WR-1065 significantly reduced their neoplastic transforming response to ⁵⁶Fe particles. This model provides an opportunity to study the cellular and molecular mechanisms involved in malignant transformation of human epithelial cells by heavy ions.