Application of the mechanical oscillator technique to the investigation of EVA decompression

The ultrasonic bubble detection technique has been used as a versatile tool in the investigation of hypobaric decompression procedures for the last two decades. However, this method can only detect relatively large bubbles > 30-50 micrometers (usually in venous blood) and not the very first stages of bubble formation. Recently, the mechanical oscillator technique has been applied in air diving trials in order to detect small blood density changes due to hypothetical fluid shifts. However, sharp density drops were found in the decompression process, and these have been attributed to gas bubble formation. In this study, this method was applied together with Doppler controls to a series of altitude decompressions to 300 and 500 hPa, which represents the range of EVA operational pressures currently used or planned. Six subjects participated in both series; the oscillator sample tube could be pressurized. By the application of pressure on a blood sample containing questionable gas bubbles, these are reduced in volume, like in recompression therapy, and thus the density of the sample is increased. This effect has been shown in all 6 subjects undergoing decompression to 300 hPa, whereas in the 500 hPa series only 3 out of 6 subjects corresponded with gas phase formation immediately after decompression. Typically, Doppler bubbles appeared only after some latency time between 20 and 60 min; after this time, the density effect had nearly vanished. It is concluded that the mechanical oscillator technique represents a complementary research instrument to the Doppler method, because it is able to deliver a quantitative resolution of the early stage of gas phase formation.     

Results of space experiment program "Interferon"

The results of the biological space experiment "Interferon" performed by two international cosmonaut teams (26 May 1980, and 16 May 1981) aboard space laboratory Solyut-6 are reported: (1) Human lymphocytes separated from blood of healthy donors and placed into "Interferon I" equipment could be kept for 7 days in suspension culture under spaceflight conditions. Interferon production could be induced in human lymphocytes by preparations of different origin: virus, synthetic polyribonucleotides, bacterial protein and plant pigment. An increased lymphocyte interferon production in space laboratory compared to ground control was observed. (2) Human interferon preparations and interferon inducers placed in space laboratory at room temperature for 7 days maintained their biological activity. (3) A decrease of induced interferon production and natural killer activity of lymphocytes isolated from peripheral blood of cosmonauts was observed on the 1st day on Earth after 7-days spaceflight.     

Precision bone and muscle loss measurements by advanced, multiple projection DEXA (AMPDXA) techniques for spaceflight applications.

An advanced, multiple projection, dual energy x-ray absorptiometry (AMPDXA) scanner system is under development. The AMPDXA is designed to make precision bone and muscle loss measurements necessary to determine the deleterious effects of microgravity on astronauts as well as develop countermeasures to stem their bone and muscle loss. To date, a full size test system has been developed to verify principles and the results of computer simulations. Results indicate that accurate predictions of bone mechanical properties can be determined from as few as three projections, while more projections are needed for a complete, three-dimensional reconstruction.     

Envelope Threshold Detection in a Class of Non-Gaussian Interference

This paper considers the detection of a sinusoidal or chirp signal imbedded in wideband FM interference (as might be generated by some types of active jamming), such that after pulse compression or other integration, the interference can be approximated by a sum of sinusoids of independent phase. The detection probability in such non-Gaussian noise is compared to that for Gaussian noise, with the Gaussian result approached, as required, in the limit that the number of sinusoids in the sum increases without bound. For detection using a comparison of the envelope with a threshold which yields a given false-alarm probability (CFAR detection), the detection probability is improved over the case of Gaussian noise, so that the usual approach basing the design on Gaussian noise would be conservative. Using a threshold determined from the envelope mean, the FM interference yields a lower false-alarm probability than for Gaussian noise, with detection probability only slightly degraded.     

Application of the Concept of Referenced Radio Navigation

This paper discusses referenced radio navigation, the concept whereby monitoring stations at known locations are used to calibrate out systematic errors in a navigation system. This concept is implemented by broadcasting calibration data to the navigating user for application as real-time corrections to the position fixes made by the user's basic navigation equipment. A method is suggested for the automatic transmission and receiver processing of the correction data. Referenced radio navigation overcomes many of the shortcomings generally associated with long-distance navigation systems, and can increase accuracy and repeatability significantly. The concept is particularly applicable to global navigation systems such as OMEGA, in which propagation or synchronization errors can contribute substantially to the system error budget.     

Detection of Known Signals in Nonstationary Noise

The basic design of a nonlinear, time-invariant filter is postulated for detecting signal pulses of known shape imbedded in nonstationary noise. The noise is a sample function of a Gaussian random process whose statistics are approximately constant during the length of a signal pulse. The parameters of the filter are optimized to maximize the output signal-to-noise ratio (SNR). The resulting nonlinear filter has the interesting property of approximating the performance of an adaptive filter in that it weights each frequency band of each input pulse by a factor that depends on the instantaneous noise power spectrum present at that time. The SNR at the output of the nonlinear filter is compared to that at the output of a matched filter. The relative performance of the nonlinear system is good when the signal pulses have large time-bandwidth products and the instantaneous noise power spectrum is colored in the signal pass band.     

Activity of the sympathetic-adrenomedullary system in rats after space flight on the COSMOS biosatellites

The indicators of adrenomedullary activity (catecholamine content (CA) and the activity of the catecholamine-synthesizing enzymes tyrosine hydroxylase (TH) and dopamine-β-hydroxylase (DBH)) were measured in the adrenal glands of rats living in a state of weightlessness for 18.5–19.5 days on board the biosatellites COSMOS 936 and COSMOS 1129. None of these indicators was significantly changed by space flight, neither in the group living in a state of weightlessness nor in the group living in a centrifuge on board the spacecraft and exposed to artificial gravity of 1 g (COSMOS 936). Animals exposed after space flight to repeated immobilization stress on Earth showed a significant decrease of adrenal adrenaline and an appreciable increase in adrenal TH activity compared to stressed animals which were not in space. These results suggest that a prolonged state of weightlessness during space flight does not by itself represent an intensive stressful stimulus for the adrenomedullary system but potentiates the response of cosmonauts to stress after return to Earth.     

Observations of 1–30 MeV gamma rays from the galactic center

Preliminary results are reported for gamma ray observations of the galactic center region made during a 15 hour balloon flight from Alice Springs, Australia on April 18, 1979. The observations were carried out with the UCR double-scatter gamma-ray telescope at energies of 1 to 30 MeV. The observations are compatible with a galactic source of approximately equal brightness along the region 300°<ℓII<60°. The energy distribution joins smoothly to previous spark chamber results at energies above 30 MeV and to scintillator results below 1 MeV. It appears to be a combination of nuclear gamma ray lines superimposed on a bremsstrahlung spectrum with a power law (1.3±.7) × 10⁻³ E⁻(^1.7±.2). The ¹²C* line at 4.4 MeV appears to be present with a significance of about 16σ. The flux in the line is (6±3) × 10⁻⁴photons cm⁻²s⁻¹rad⁻¹. The oxygen line at 6.1 MeV does not seem to appear significantly above background.     

The nighttime mid-latitude foF2 and geomagnetic indices

The correlation between AE, Ap and Dst indices, on the one hand, and nighttime critical frequencies, on the other, in northern midlatitudes in investigated. The correlation is closest for the Dst-index. A possible mechanism involving the effect of ring currents on the electron density in the mid-latitude F-region is mentioned.     

CELSS transportation analysis

Regenerative life support systems based on the use of biological material have been considered for inclusion in manned spacecraft since the early days of the United States space program. These biological life support systems are currently being developed by NASA in the Controlled Ecological Life Support System (CELSS) program. Because of the progress being achieved in the CELSS program, it is time to determine which space missions may profit from use of the developing technology. This paper presents the results of a study that was conducted to estimate where potential transportation cost savings could be anticipated by using CELSS technology for selected future manned space missions.

Six representative missions were selected for study from those included in NASA planning studies. The selected missions ranged from a low Earth orbit mission to those associated with asteroids and a Mars sortie. The crew sizes considered varied from four persons to five thousand. Other study parameters included mission duration and life support closure percentages, with the latter ranging from complete resupply of consumable life support materials to 97% closure of the life support system. The paper presents the analytical study approach and describes the missions and systems considered, together with the benefits derived from CELSS when applicable.