Accumulation of tumor suppressor p53 in rat muscle after a space flight.

Tumor suppressor p53 functions as a cell cycle checkpoint under stressful conditions. Early studies have shown that genotoxic stress activates p53 pathway. Recently, many kinds of non-genotoxic stress such as heat shock, cold shock, and low pH also have been found to activate p53 pathway. The effects on living organism remains to be explored. Here, we show that an 18-day space flight induced a 3.6 fold accumulation of p53 in rat skeletal muscle. This results suggests that the p53 pathway plays a role in safeguarding genomic stability against the stressful space environments and supports our previous observation of p53 accumulation in rat skin after a space flight.     

Rocket observation of the ultraviolet spectrum of comet Halley

An ultraviolet sounding rocket telescope/spectrograph experiment observed Comet Halley on 26 February 1986, 17 days after perihelion. From the long-slit spectra, the production rates of O, C, and CO are calculated. The derived water production rate is a lower limit of 5.0 × 10²⁹ s⁻¹ and the volume mixing ratio of CO to H₂O is 21%. The predicted brightness distribution from a radial outflow model with H₂O and CO as parent molecules are in accordance with the measured spatial profiles of OI and CO emissions. The ratio of the production rates of CO to C is 2.7 which is consistent with the carbon source being the photodissociation of CO. However, the radial outflow model which best fits the CO data predicts significantly weaker CI emissions than was observed. A better fit to the carbon data is found when an inner coma source of C at a rate of 3% of the water production rate is included in the model.     

ETS-II Experiments Part III: Weather Radar System

The weather radar system used in conjunction with Earth-satellite propagation experiments for quantifying rainfall rate in a unit volume, determined by the beamwidth and the pulselength, is described. Firstly, methods for deriving rainfall rate per unit volume are stated in detail with special emphasis on calibration to determine unknown parameters associated with propagation losses in waveguides and the atmosphere. The calibration method is somewhat different from a conventional one but is useful for routine observation. Secondly, in addition to a simple explanation of the hardware of this radar system, the data modes, developed for measuring rainfall rate along the propagation path and radar reflectivity factor in the horizontal and vertical cross sections around the station are described. These data modes are effectively combined by the operational scanning modes for routine observation of propagation experiments, while each data mode can also be operated independently. Examples obtained by each data mode are also given.     

Conceptual design of a hypervelocity asteroid intercept vehicle (HAIV) and its flight validation mission

An intercept mission with nuclear explosives is the most effective of the practical mitigation options against the impact threat of near-Earth objects (NEOs) with a short warning time (e.g., much less than 10 years). The existing penetrated subsurface nuclear explosion technology limits the intercept velocity to less than approximately 300 m/s. Consequently, an innovative concept of blending a hypervelocity kinetic impactor with a subsurface nuclear explosion has been developed for optimal penetration, fragmentation, and dispersion of the target NEO. A proposed hypervelocity asteroid intercept vehicle (HAIV) consists of a kinetic-impact leader spacecraft and a follower spacecraft carrying nuclear explosives. This paper describes the conceptual development and design of a baseline HAIV system and its flight validation mission architecture for three mission cost classifications (e.g., $500 M, $1 B, and $1.5 B).     

Acceleration of solar cosmic rays and the fine spectral structure of type II radio bursts

On the basis of data, obtained by means of the ground-based solar service RSTN (Radio Solar Telescope Network) and the geostationary satellite system GOES, the relationship between the solar cosmic rays (SCR) intensity I _p with the proton energy E _p > 1 MeV and parameters of meter-decameter type II radio bursts in the frequency range of 25–180 MHz is studied. The process of proton acceleration by shock waves was characterized by the frequency drift velocity of radio bursts V _mII and the relative difference between radio emission frequencies at the first two harmonics b. It is shown that the coefficient of correlation between I _p and b increases with E _p growing from 0.40 to 0.70, while a similar coefficient between I _p and V _mII does not exceed 0.30. Indications in favor of the two-stage SCR acceleration model are obtained.     

The SEVAN Worldwide network of particle detectors: 10 years of operation

The Space Environment Viewing and Analysis Network (SEVAN) aims to improve the fundamental research on particle acceleration in the vicinity of the sun, on space weather effects and on high-energy physics in the atmosphere and lightning initiation. This new type of a particle detector setup simultaneously measures fluxes of most species of secondary cosmic rays, thus being a powerful integrated device for exploration of solar modulation effects and electron acceleration in the thunderstorm atmosphere. The SEVAN modules are operating at the Aragats Space Environmental Center (ASEC) in Armenia, in Croatia, Bulgaria, Slovakia, the Czech Republic (from 2017) and in India. In this paper, we present the most interesting results of the SEVAN network operation during the last decade. We present this review on the occasion of the 10th anniversary of the International Heliophysical Year in 2007.     

Common-Mode Noise Generation in a DC-to-DC Converter

Analytical and experimental considerations of the common-mode noise in a dc-to-dc connverterare discussed. Analyzing the mechanism of the common-mode noise generation by means of a high-frequency equivalent circuit, we estimate the output noise voltage generated during the transistor's turn-on time. This commonmode noise consists mainly of two frequency components distributed in several megahertz. The effects of parasitic parameters on the noise voltage and frequencies are clarified. In addition, the effect of a common-mode choke on the noise suppression is discussed experimentally.     

A Method of Measuring Hydrogen Isotopes in Surface Layers of Planetary Soils by Spectroscopy of Recoil Protons in Alpha Particle Elastic Scattering

A theoretical and experimental feasibility study of possible determination of the hydrogen and deuterium concentrations in the surface layers of planetary bodies is presented. The method under study is the recoil proton and deuteron spectrometry of forward scattering in the course of elastic interaction of alpha particles with the nuclei of hydrogen isotopes. The spectra of recoil protons and deuterons were recorded using a prototype model of a hydrogen spectrometer, and these spectra were used to determine the hydrogen concentrations in the samples of different compositions.     

The dynamics of blood biochemical parameters in cosmonauts during long-term space flights

Most of the previously obtained data on cosmonauts' metabolic state concerned certain stages of the postflight period. In this connection, all conclusions, as to metabolism peculiarities during the space flight, were to a large extent probabilistic. The purpose of this work was study of metabolism characteristics in cosmonauts directly during long-term space flights. In the capillary blood samples taken from a finger, by "Reflotron IV" biochemical analyzer, "Boehringer Mannheim" GmbH, Germany, adapted to weightlessness environments, the activity of GOT, GPT, CK, gamma-GT, total and pancreatic amylase, as well as concentration of hemoglobin, glucose, total bilirubin, uric acid, urea, creatinine, total, HDL- and LDL cholesterol, triglycerides had been determined. HDL/LDL-cholesterol ratio also was computed. The crewmembers of 6 main missions to the "Mir" orbital station, a total of 17 cosmonauts, were examined. Biochemical tests were carried out 30-60 days before launch, and in the flights different stages between the 25-th and the 423-rd days of flights. In cosmonauts during space flight had been found tendency to increase, in compare with basal level, GOT, GPT, total amylase activity, glucose and total cholesterol concentration, and tendency to decrease of CK activity, hemoglobin, HDL-cholesterol concentration, and HDL/LDL - cholesterol ratio. Some definite trends in variations of other determined biochemical parameters had not been found. The same trends of mentioned biochemical parameters alterations observed in majority of tested cosmonauts, allows to suppose existence of connection between noted metabolic alterations with influence of space flight conditions upon cosmonaut's body. Variations of other studied blood biochemical parameters depends on, probably, pure individual causes.