Neutral buoyancy and sleep-deprived serum factors alter expression of cytokines regulating osteogenesis

We examined expression of genes associated with cytokine production, and genes implicated in regulating bone metabolism, in bone stromal and osteoblast cells incubated under standard ground conditions and under conditions of neutral buoyancy, and in the presence/absence of serum from normal or sleep-deprived mice. We observed a clear interaction between these two conditions (exposure to neutral buoyancy and serum stimulation) in promoting enhanced osteoclastogenesis. Both conditions independently altered expression of a number of cytokines implicated in the regulation of bone metabolism. However, using stromal cells from IL-1 and TNFx cytokine(r) KO mice, we concluded that the increased bone loss under microgravity conditions was not primarily cytokine mediated.     

Orbit determination of BDS-3 satellite based on regional ground tracking station and inter-satellite link observations

The BeiDou global navigation satellite system (BDS-3) has established the Ka-band inter-satellite link (ISL) to realize a two-way ranging function between satellites, which provides a new observation technology for the orbit determination of BDS-3 satellites. Therefore, this study presents a BDS satellite orbit determination model based on ground tracking station (GTS) observations and ISL ranging observations firstly to analyze the impact of the ISL ranging observations on the orbit determination of BDS-3 satellites. Subsequently, considering the data fusion processing, the variance component estimation (VCE) algorithm is applied to the parameter estimation process of the satellite orbit determination. Finally, using the measured data from China’s regional GTS observations and BDS-3 ISL ranging observations, the effects of ISL ranging observations on the orbit determination accuracy of BDS-3 satellites are analyzed. Moreover, the impact of the VCE algorithm on the fusion data processing is evaluated from the aspects of orbit determination accuracy, Ka-band hardware delay parameter stability, and ISL ranging observation residuals. The results show that for China’s regional GTSs, the addition of BDS-3 ISL ranging observations can significantly improve the orbit determination accuracy of BDS-3 satellites. The observed orbit determination accuracy of satellite radial component is improved from 48 cm to 4.1 cm. In addition, when the initial weight ratio between GTS observations and ISL ranging observations is not appropriate, the various indicators which include orbit determination accuracy, ISL hardware delay, and ISL observation residuals were observed to have improved after the adjustment of the VCE algorithm. These results validate the effectiveness of the VCE algorithm for the fusion data processing of the GTS observations and ISL ranging observations.     

A method of estimating GPS instrumental biases with a convolution algorithm

This paper presents a method of deriving the instrumental differential code biases (DCBs) of GPS satellites and dual frequency receivers. Considering that the total electron content (TEC) varies smoothly over a small area, one ionospheric pierce point (IPP) and four more nearby IPPs were selected to build an equation with a convolution algorithm. In addition, unknown DCB parameters were arranged into a set of equations with GPS observations in a day unit by assuming that DCBs do not vary within a day. Then, the DCBs of satellites and receivers were determined by solving the equation set with the least-squares fitting technique. The performance of this method is examined by applying it to 361?days in 2014 using the observation data from 1311 GPS Earth Observation Network (GEONET) receivers. The result was crosswise-compared with the DCB estimated by the mesh method and the IONEX products from the Center for Orbit Determination in Europe (CODE). The DCB values derived by this method agree with those of the mesh method and the CODE products, with biases of 0.091?ns and 0.321?ns, respectively. The convolution method's accuracy and stability were quite good and showed improvements over the mesh method.     

同步双小行星系统共振轨道设计

研究了同步双小行星系统中共振轨道的设计方法及演化规律。首先，基于双椭球模型建立探测器运动方程，并给出共振轨道初值选取方法。然后，利用改进并行打靶法，提出一种双小行星系统平面共振轨道两步修正方法。同时结合稳定性理论及分岔理论，给出双小行星系统三维共振轨道生成和延拓方法；最后，以双小行星系统1999KW4为例，设计了共振比为1∶1,1∶2,1∶3,1∶4,2∶3的平面和空间共振轨道族，并分析了共振轨道的特性及轨道周期和轨道能量的变化规律。给出的双小行星系统中共振轨道的设计方法具有普适性，对未来双小行星系统探测任务中的轨道设计具有一定的参考意义与借鉴价值。     

双燃式冲压发动机中超燃燃烧室冷态流场数值模拟

采用Ｍａｃ Ｃｏｒｍ ａｃｋ 矢通分裂格式, 求解雷诺平均的Ｎ－Ｓ方程组, 采用Ｂａｌｄｗ ｉｎ－Ｌｏ－ｍ ａｘ 代数湍流模型和混合长度模型, 模拟超燃燃烧室内两股平行超声速来流的冷态流场, 取得了与试验相一致的结果, 计算表明回流区和射流流动参数对超燃燃烧室流场内波系的变化有着较大的影响。     

地下原油无缆电加热系统可靠性措施的计算机仿真与优化决策

本文根据给定的油井地质资料,用计算机对其进行拟合再现,着重讨论了井下原油无缆电加热系统的可靠性措施及其计算机仿真与优化决策方法。     

基于神经网络的机械加工信息融合

概述了基于神经网络的信息融合技术在机械加工中的刀具状态监控、加工精度预测、误差补偿等方面的应用,并展望了该技术的应用前景。     

Single-phase three-level rectifier and random PWM inverter drives

A novel ac/dc/ac converter topology with three-level pulsewidth modulated (PWM) scheme for the single-phase ac/dc rectifier and random PWM scheme for ac drives is proposed. In order to improve the power quality in the single-phase rectifier, a ROM-based (read-only memory) control scheme, based on hysteresis current comparator, region detector, and capacitor compensator, is used to achieve a sinusoidal line current with low current distortion. The control scheme of the adopted three-level rectifier is easy to implement. The blocking voltage of power switches is clamped to half of the dc bus voltage. To reduce the mechanical vibration from an induction motor, random pulse position PWM scheme is adopted to spread the harmonics in a wide frequency range which results in the reduction of torque pulsation in the ac motor drives. Simulation and experimental results based on the laboratory prototype circuit are presented to verify the proposed control scheme     

分析计算航天飞机气动系数的边界元局部方法

空间运载工具设计阶段为分析比较不同外形高超音速各流动领域的性能,广泛应用局部方法。在其原始形式下,形状函数计算繁复,并限于简单几何外形组成的轴对称体。用边界元局部方法进行形状函数计算,可免去原局部方法面积分的繁复和藉助表格的局限。对STS-1轨道飞行器外形进行计算得到丁形状函数,并根据实验数据确定领域系数。由此计算出飞行器的法向力、轴向力和俯仰力矩系数,计算结果与实验数据相符。     

起落架双腔缓冲器初始压力的优化设计

本文提出并讨论了起落架双腔缓冲器的初始压力优化设计问题,给出了分析模型与方法。国产某运输机起落架改双腔的算例表明,该模型与方法是可行的。