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861.
E.S. Seo T. Anderson D. Angelaszek S.J. Baek J. Baylon M. Buénerd M. Copley S. Coutu L. Derome B. Fields M. Gupta J.H. Han I.J. Howley H.G. Huh Y.S. Hwang H.J. Hyun I.S. Jeong D.H. Kah K.H. Kang D.Y. Kim H.J. Kim K.C. Kim M.H. Kim K. Kwashnak J. Lee M.H. Lee J.T. Link L. Lutz A. Malinin A. Menchaca-Rocha J.W. Mitchell S. Nutter O. Ofoha H. Park I.H. Park J.M. Park P. Patterson J.R. Smith J. Wu Y.S. Yoon 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2014
The Cosmic Ray Energetics And Mass (CREAM) instrument is configured with a suite of particle detectors to measure TeV cosmic-ray elemental spectra from protons to iron nuclei over a wide energy range. The goal is to extend direct measurements of cosmic-ray composition to the highest energies practical, and thereby have enough overlap with ground based indirect measurements to answer questions on cosmic-ray origin, acceleration and propagation. The balloon-borne CREAM was flown successfully for about 161 days in six flights over Antarctica to measure elemental spectra of Z = 1–26 nuclei over the energy range 1010 to >1014 eV. Transforming the balloon instrument into ISS-CREAM involves identification and replacement of components that would be at risk in the International Space Station (ISS) environment, in addition to assessing safety and mission assurance concerns. The transformation process includes rigorous testing of components to reduce risks and increase survivability on the launch vehicle and operations on the ISS without negatively impacting the heritage of the successful CREAM design. The project status, including results from the ongoing analysis of existing data and, particularly, plans to increase the exposure factor by another order of magnitude utilizing the International Space Station are presented. 相似文献
862.
L Sciola M Cogoli-Greuter A Cogoli A Spano P Pippia 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1999,24(6):801-805
The effects of microgravity on Jurkat cells--a T-lymphoid cell line--was studied on a sounding rocket flight. An automated pre-programmed instrument permitted the injection of fluorescent labelled concanavalin A (Con A), culture medium and/or fixative at given times. An in-flight 1 g centrifuge allowed the comparison of the data obtained in microgravity with a 1 g control having the same history related to launch and re-entry. After flight, the cells fixed either at the onset of microgravity or after a or 12 minute incubation time with fluorescent concanavalin A were labelled for vimentin and actin and analysed by fluorescence microscopy. Binding of Con A to Jurkat cells is not influenced by microgravity, whereas patching of the Con A receptors is significantly lower. A significant higher number of cells show changes in the structure of vimentin in microgravity. Most evident is the appearance of large bundles, significantly increased in the microgravity samples. No changes are found in the structure of actin and in the colocalisation of actin on the inner side of the cell membrane with the Con A receptors after binding of the mitogen. 相似文献
863.
M Schwarzenberg P Pippia M A Meloni G Cossu M Cogoli-Greuter A Cogoli 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1999,24(6):793-800
In this paper we discuss the effect of microgravity on T cells and we present the data of studies with two new machines for 0 g simulations. Several experiments in space show that mitogenic T cell activation is lost at 0 g. Immunocytochemistry indicates that such effect is associated with changes of the cytoskeleton. Biochemical studies suggest that the lack of expression of the interleukin-2 receptor is one of the major causes of the loss of activity. In fact, interleukin-2 is the third signal required for full activation. In order to deepen our investigations we are now working with the free-fall machine, FFM, invented by D. Mesland, and with the random positioning machine, RPM, or three-dimensional clinostat, developed by T. Hoson. The FFM produces periods of free-fall lasting approximately 800 ms followed by bounces of 15-30 g lasting 45-60 ms. The RPM eliminates the effect of gravity by rotating biological specimen randomly around two orthogonal axes. While the FFM failed to reproduce the results obtained with T lymphocytes in space, the data from the RPM are in good agreement with those in real microgravity. In fact, the inhibition of the mitotic index in the RPM is 89% compared to static controls. The RPM (as the FFM) can carry markedly larger specimen than the fast rotating clinostat and thus allows to conduct comprehensive studies to select suitable biological objects for further investigations in space. 相似文献
864.
P G Vekilov 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1999,24(10):1231-1240
Protein crystals, grown under reduced gravity conditions, are either superior or inferior in their structural perfection than their Earth-grown counterparts. A reduction of the crystals' quality due to low-gravity effects on the growth processes cannot be understood from existing models. In this paper we put forth a rationale which predicts either advantages or disadvantages of microgravity growth. This rationale is based on the changes in the effective solute and impurity supply rates in microgravity and their effects on the intrinsic growth rate fluctuations that arise from the coupling of bulk transport to nonlinear interfacial kinetics and cause severe inhomogeneities. Depending on the specific diffusivity and kinetic coefficient of a protein and the impurities in the solution, either transport enhancement through forced flow or transport suppression under reduced gravity can result in a reduction of the kinetic fluctuations and, thus, growth with higher structural perfection. Investigating this mechanism of microgravity effects, we first demonstrate a one-to-one correspondence between these fluctuations, that are due to the bunching of growth steps, and the formation of defects in the crystals. We have confirmed the forced flow aspects of this rationale in ground-based experiments with lysozyme utilizing flowing solutions with varying, well characterized impurity contents. 相似文献
865.
M Andre P Chagvardieff 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1999,24(3):265-269
During the past 10 years, the main part of CELSS studies has concerned the exploration of limits of plant productivity. Very high yields were obtained in continuous and high lighting, without reaching any limit. Concepts of mineral nutrition were renewed. CELSS activities now induce a development in the techniques of image processing applied to plants in order to follow the growth, to detect stresses or diseases or to pilot harvesting robots. Notable efforts concern the development of sensors, the study of trace contaminants and the micro-organisms monitoring. In parallel, several instruments for plant culture in closed Systems were developed. The advantages of closure are emphasised in comparison with open flow systems. The concept of Artificial Ecosystems developed for space research is more and more taken into account by the scientific community. It is considered as a new tool to study basic and applied problems related to ecology and not especially concerned with space research. 相似文献
866.
In this paper, a process of flanging to create thin-walled axisymmetrical shells with the shape of truncated cone is analyzed. Also presented are some dependences that make it possible to determine the relative depth of a formed piece at the given piece-blank thickness ratio. 相似文献
867.
E. V. Kasumov 《Russian Aeronautics (Iz VUZ)》2013,56(3):224-228
A possibility of evaluating dynamic response of a mechanical system to controlling actions of the automatic stabilization and control system is considered on the basis of a numerical experiment. Examples of design analysis are presented for a light-weight helicopter in which an autopilot is part of the control system. The finite element analysis is used in this paper. 相似文献
868.
Current projects of manned missions to Mars are aimed to their realization in the second-third decades of this century. The purpose of this paper is to determine and review the main biomedical problems, that require a first and foremost decision for safety support of extravehicular activity (EVA) carried out by crewmembers of the Mars expedition. To a number of such problems the authors of the paper attribute a creation of adequate EVA equipment intended, first, for assembly of interplanetary spacecraft on the Earth orbit, performance of maintenance operations and scientific researches on the external surface of spacecraft during interplanetary flight and, secondly, for work on the Mars surface. New generation of space suits with low weight, high mobility and acceptable risk of decompression sickness must be as a central component of EVA equipment. The program for preparation to a Mars expedition also has to include special investigations in order to design the means and methods for a reliable protection of crew against space radiation, to elaborate the approach to medical monitoring and primary medical care during autonomous space mission, to maintain good health condition of crewmembers during EVA under the Mars gravity (0.38 g) after super long-term flight in weightlessness. 相似文献
869.
Ch. I. Chaban R. T. Ripetskyj E. L. Kordyum N. A. Kit 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1999,23(12):2011-2016
Under gravistimulation, dark-grown protonemata of Pottia intermedia revealed negative gravitropism with a growth rate of approximately 28 μm·h−1 at room temperature (20 °C). In 7 days, the protonema formed a bundle of vertically oriented filaments. At an elevated temperature (30 °C), bundles of vertically growing filaments were also formed. However, both filament growth rate and amplitude of the gravicurvature were reduced. Red light (RL) irradiation induced a positive phototropism of most apical protonemal cells at 20 °C. In a following period of darkness, approximately two-thirds of such cells began to grow upward again, recovering their negative gravitropism. RL irradiation at the elevated temperature caused a partial increase in the number of protonemal cells with negative phototropism, but the protonemata did not exhibit negative gravitropism after transfer to darkness. The negative gravitropic reaction was renewed only when protonemata were placed at 20 °C. A dramatic decrease in starch amount in protonemal apical cells, which are sensitive to both gravity and light, occurred at the higher temperature. Such a decrease may be one of the reasons for the inhibition of the protonemal gravireaction at the higher temperature. The observation has a bearing on the starch-statolith theory. 相似文献
870.