Effect of track structure and radioprotectors on the induction of oncogenic transformation in murine fibroblasts by heavy ions

The oncogenic potential of high-energy ⁵⁶Fe particles (1 GeV/nucleon) accelerated with the Alternating Gradient Synchrotron at the Brookhaven National Laboratory was examined utilizing the mouse C3H 10T1/2 cell model. The dose-averaged LET for high-energy ⁵⁶Fe is estimated to be 143 keV/μm with the exposure conditions used in this study. For ⁵⁶Fe ions, the maximum relative biological effectiveness (RBE_max) values for cell survival and oncogenic transformation were 7.71 and 16.5 respectively. Compared to 150 keV/μm ⁴He nuclei, high-energy ⁵⁶Fe nuclei were significantly less effective in cell killing and oncogenic induction. The prostaglandin E₁ analog misoprostol, an effective oncoprotector of C3H 10T1/2 cells exposed to X rays, was evaluated for its potential as a radioprotector of oncogenic transformation with high-energy ⁵⁶Fe. Exposure of cells to misoprostol did not alter ⁵⁶Fe cytotoxicity or the rate of ⁵⁶Fe-induced oncogenic transformation.     

Features of rotational motion of a spacecraft descending in the Martian atmosphere

Angular motion at atmospheric entry is studied in the paper for a spacecraft with a bi-harmonic moment characteristic. Special attention is given to the case when the spacecraft possesses two stable balanced positions, and, hence, it can oscillate in dense atmospheric layers in the ranges of small or large angles of attack. The averaged equations of spacecraft motion are derived, which allow one to increase the speed of calculations by several orders of magnitude. A real example is presented, which concerns a spacecraft specially designed for descending in the Martian atmosphere.     

Behavior of tethered debris with flexible appendages

Active exploration of the space leads to growth of a near-Earth space pollution. The frequency of the registered collisions of space debris with functional satellites highly increased during last 10 years. As a rule a large space debris can be observed from the Earth and catalogued, then it is possible to avoid collision with the active spacecraft. However every large debris is a potential source of a numerous small debris particles. To reduce debris population in the near Earth space the large debris should be removed from working orbits. The active debris removal technique is considered that intend to use a tethered orbital transfer vehicle, or a space tug attached by a tether to the space debris. This paper focuses on the dynamics of the space debris with flexible appendages. Mathematical model of the system is derived using the Lagrange formalism. Several numerical examples are presented to illustrate the mutual influence of the oscillations of flexible appendages and the oscillations of a tether. It is shown that flexible appendages can have a significant influence on the attitude motion of the space debris and the safety of the transportation process.     

"Signal" search for intelligence in the galactic nucleus with the array of the Lowlands

In August, 1981, the Westerbork Synthesis Radio Telescope was used for 4 h to search for narrowband pulsing radio beacons in the direction of the Galactic Center. By using both the spatial discrimination and temporal stability available to an interferometric measurement, weak intermittent signals can be detected even in the face of the strong, naturally caused radiation from this region. A radio beacon within our bandwidth, centered on the 21 cm neutral hydrogen line, would be recognizable if it had a repetition period between 40 sec and 1/2 h. The rms sensitivity to point sources was approximately 50 mJy/cycle, and the detection limit was 500 mJy/cycle. The limit degrades for pulse widths < 0.02s. No repetitive signals were found. For a swept, narrow-band radio beacon constrained to the Galactic Disk (beamwidth = 0.02 rad), our detection limit corresponds to a transmitter power of 10(11) MW at the Galactic Center.     

Design of the HEAO Main Bus Shunt Regulator

The High Energy Astronomy Observatory (HEAO) main bus regulator contains a redundant error amplifier (REA) and a 12-section sequenced shunt transconductance amplifier (STA) in which not more than three and not less than one shunt section are in an active control mode regardless of a failure in any one of the twelve sections. The part of the work concerned with the shaping of the frequency response of the REA and STA minor feedback loops and of the teolator major feedback loop is described. Emphasis is on the application of a general design technique embodying a "design-analyze-measure iteration loop," in which a first-cut design and analysis is corrected ard improved after experimental observation of discrepancies and deficiencies. In particular, an incipient high-frequency oscillation was thereby reliably eliminated. It is demonstrated that analysis techniques involving a minimum of algebra can provide full quantitative information on an efficient and reliable system design.