Metabolic assessments during extra-vehicular activity

Extra-vehicular activity (EVA) has a significant role during extended space flights. It demonstrates that humans can survive and perform useful work outside the Orbital Space Stations (OSS) while wearing protective space suits (SS). When the International Space Station 'Alpha' (ISSA) is fully operational, EVA assembly, installation, maintenance and repair operations will become an everyday repetitive work activity in space. It needs new ergonomic evaluation of the work/rest schedule for an increasing of the labor amount per EVA hour. The metabolism assessment is a helpful method to control the productivity of the EVA astronaut and to optimize the work/rest regime. Three following methods were used in Russia to estimate real-time metabolic rates during EVA: 1. Oxygen consumption, computed from the pressure drop in a high pressure bottle per unit time (with actual thermodynamic oxygen properties under high pressure and oxygen leakage taken into account). 2. Carbon dioxide production, computed from CO2 concentration at the contaminant control cartridge and gas flow rate in the life support subsystem closed loop (nominal mode) or gas leakage in the SS open loop (emergency mode). 3. Heat removal, computed from the difference between the temperatures of coolant water or gas and its flow rate in a unit of time (with assumed humidity and wet oxygen state taken into account). Comparison of heat removal values with metabolic rates enables us to determine the thermal balance during an operative medical control of EVA at "Salyut-6", "Salyut-7" and "Mir" OSS. Complex analysis of metabolism, body temperature and heat rate supports a differential diagnosis between emotional and thermal components of stress during EVA. It gives a prognosis of human homeostasis during EVA. Available information has been acquired into an EVA data base which is an effective tool for ergonomical optimization.     

Production of neutrons from interactions of GCR-like particles

In order to help assess the risk to astronauts due to the long-term exposure to the natural radiation environment in space, an understanding of how the primary radiation field is changed when passing through shielding and tissue materials must be obtained. One important aspect of the change in the primary radiation field after passing through shielding materials is the production of secondary particles from the breakup of the primary. Neutrons are an important component of the secondary particle field due to their relatively high biological weighting factors, and due to their relative abundance, especially behind thick shielding scenarios. Because of the complexity of the problem, the estimation of the risk from exposure to the secondary neutron field must be handled using calculational techniques. However, those calculations will need an extensive set of neutron cross section and thicktarget neutron yield data in order to make an accurate assessment of the risk. In this paper we briefly survey the existing neutron-production data sets that are applicable to the space radiation transport problem, and we point out how neutron production from protons is different than neutron production from heavy ions. We also make comparisons of one the heavy-ion data sets with Boltzmann-Uehling-Uhlenbeck (BUU) calculations.     

Muscle atrophy associated with microgravity in rat: basic data for countermeasures

Morphological, contractile properties and myosin heavy chain (MHC) composition of rat soleus muscles were studied after 2 weeks of unloading (HS) and after 2 weeks of HS associated with selective deafferentation (HS + DEAF) at the level L4 and L5. The same significant reductions in muscle mass and tetanic tension were found after HS and HS + DEAF. However, the transformation of the slow-twitch soleus muscle towards a faster type characterized by a decrease in twitch time parameters and an increase in fast-twitch type MHC isoforms in HS did not appear in HS + DEAF conditions. Our results also showed that a pattern similar to firing rate of motoneurones innervating slow-twitch muscles inhibited the slow to fast fiber changes observed during HS. Nevertheless, neither the loss of mass or force output in the HS muscles were prevented by electrostimulation. Immobilization in a stretched position during HS maintained the muscle wet weight, mechanical and electrophoretical characteristics close to control values. We concluded that the decrease in mechanical strains imposed on the muscle during unloading was the main factor for the development of atrophy, while the kinetic changes might be predominantly modulated by the nervous command. These basic data suggested that some experimental conditions such as electrostimulation or stretching, could participate in countermeasure programmes.     

MEDES clinical research facility as a tool to prepare ISSA space flights

This new multi-disciplinary medical experimentation center provides the ideal scientific, medical and technical environment required for research programs and to prepare international space station Alpha (ISSA) missions, where space and healthcare industries can share their expertise. Different models are available to simulate space flight effects (bed-rest, confinement,...). This is of particular interest for research in Human psychology, physiology, physiopathology and ergonomics, validation of biomedical materials and procedures, testing of drugs, and other healthcare related products. This clinical research facility (CRF) provides valuable services in various fields of Human research requiring healthy volunteers. CRF is widely accessible to national and international, scientific, medical and industrial organisations. Furthermore, users have at their disposal the multi-disciplinary skills of MEDES staff and all MEDES partners on a single site.     

Positive consequences of SETI before detection

Even before a signal is detected, six positive consequences will result from the scientific search for extraterrestrial intelligence, usually called SETI. (1) Humanity’s self-image: SETI has enlarged our view of ourselves and enhanced our sense of meaning. Increasingly, we feel a kinship with the civilizations whose signals we are trying to detect. (2) A fresh perspective: SETI forces us to think about how extraterrestrials might perceive us. This gives us a fresh perspective on our society’s values, priorities, laws and foibles. (3) Questions: SETI is stimulating thought and discussion about several fundamental questions. (4) Education: some broad-gage educational programs have already been centered around SETI. (5) Tangible spin-offs: in addition to providing jobs for some people, SETI provides various spin-offs, such as search methods, computer software, data, and international scientific cooperation. (6) Future scenarios: SETI will increasingly stimulate us to think carefully about possible detection scenarios and their consequences, about our reply, and generally about the role of extraterrestrial communication in our long-term future. Such thinking leads, in turn, to fresh perspectives on the SETI enterprise itself.     

Effect of microgravity on Escherichia coli and MS-2 bacteriophage disinfection by iodinated resins

Experiments on chemical disinfection by iodinated resins were conducted on STS 50 (USML-1), which flew a 13 day mission during 1992. Fluid processing apparatus containing microorganisms and iodinated resins was assembled in either Manhattan, Kansas, or Boulder, Colorado, and loaded on-board the Space Shuttle for the mission. Pentaiodide resin was more effective than the triiodide resin against Escherichia coli. Both resins were more effective bactericides at unit gravity than microgravity because of cosedimentation of bacteria and iodinated resin beads. In bacteriophage experiments, the triiodide resin reduced the viable titer of MS-2 by nine logs. The few viable phage surviving chemical disinfection were associated with precipitant formation in the fluid processing apparatus.     

Some problems of identifying types of large-scale solar wind and their role in the physics of the magnetosphere

This paper discusses the errors in analyzing solar-terrestrial relationships, which result from either disregarding the types of interplanetary drivers in studying the magnetosphere response on their effect or from the incorrect identification of the type of these drivers. In particular, it has been shown that the absence of selection between the Sheath and ICME (the study of so-called CME-induced storms, i.e., magnetic storms generated by CME) leads to errors in the studies of interplanetary conditions of magnetic storm generation, because the statistical analysis has shown that, in the Sheath + ICME sequences, the largest number of storm onsets fell on the Sheath, and the largest number of storms maxima fell at the end of the Sheath and the beginning of the ICME. That is, the situation is observed most frequently when at least the larger part of the main phase of storm generation falls on the Sheath and, in reality, Sheath-induced storms are observed. In addition, we consider several cases in which magnetic storms were generated by corotating interaction regions, whereas the authors attribute them to CME.     

Influence of the interplanetary magnetic field on ULF oscillations of the ionospheric resonator

A weak but statistically reliable dependence of the diurnal activity of oscillations in the ionospheric Alfvén resonator on orientation of the interplanetary magnetic field ahead of the magnetospheric front has been detected based on observations of ULF oscillations at Sayan solar observatory Mondy of the Institute of Solar–Terrestrial Physics. The interpretation of the result has been proposed. The essence is that the electromagnetic fluctuations penetrate into the magnetosphere from the interplanetary environment and influence the ionospheric resonator. The formulation of the problem and the method of solving it are part of the broad program of the experimental and theoretical study of the influence of the interplanetary magnetic field on the oscillation regime of ULF oscillations of the magnetosphere.     

Precipitation of subrelativistic-energy electrons near the polar boundary of the Earth radiation belt according to the data of measurements on the <Emphasis Type=Italic>Vernov</Emphasis> and <Emphasis Type=Italic>Lomonosov</Emphasis> satellites

The work is devoted to observations of sharp growths of magnetospheric electron fluxes in the vicinity of the polar boundary of the outer radiation belt of the Earth according to the data of measurements on the Vernov and Lomonosov satellites. This precipitation was observed at the high-latitude boundary of the outer radiation belt toward the equator from the isotropization boundary, and can be caused by scattering waves of various physical natures, including electromagnetic and electrostatic waves.     

Observation of Terrestrial gamma-ray flashes in the RELEC space experiment on the <Emphasis Type="Italic">Vernov</Emphasis> satellite

The RELEС scientific payload of the Vernov satellite launched on July 8, 2014 includes the DRGE spectrometer of gamma-rays and electrons. This instrument comprises a set of scintillator phoswich-detectors, including four identical X-ray and gamma-ray detector with an energy range of 10 kev to 3 MeV with a total area of ~500 cm² directed to the atmosphere, as well as an electron spectrometer containing three mutually orthogonal detector units with a geometric factor of ~2 cm² sr. The aim of a space experiment with the DRGE instrument is the study of fast phenomena, in particular Terrestrial gamma-ray flashes (TGF) and magnetospheric electron precipitation. In this regard, the instrument provides the transmission of both monitoring data with a time resolution of 1 s, and data in the event-by-event mode, with a recording of the time of detection of each gamma quantum or electron to an accuracy of ~15 μs. This makes it possible to not only conduct a detailed analysis of the variability in the gamma-ray range, but also compare the time profiles with the results of measurements with other RELEC instruments (the detector of optical and ultraviolet flares, radio-frequency and low-frequency analyzers of electromagnetic field parameters), as well as with the data of ground-based facility for thunderstorm activity. This paper presents the first catalog of Terrestrial gamma-ray flashes. The criterion for selecting flashes required in order to detect no less than 5 hard quanta in 1 ms by at least two independent detectors. The TGFs included in the catalog have a typical duration of ~400 μs, during which 10–40 gamma-ray quanta were detected. The time profiles, spectral parameters, and geographic position, as well as a result of a comparison with the output data of other Vernov instruments, are presented for each of candidates. The candidate for Terrestrial gamma-ray flashes detected in the near-polar region over Antarctica is discussed.