Induction of high grade astrocytoma (HGA) by protons: molecular mechanisms and RBE considerations.

Protons of a specific energy, 55 MeV, have been found to induce primary high grade astrocytomas (HGA) in the Rhesus monkey (Macaca mulatta). Brain tumors of this type were not induced by protons of other energies (32-2,300 MeV). Induction of HGA has been identified in human patients who have had radiation therapy to the head. We believe that the induction of HGA in the monkey is a consequence of dose distribution, not some unique "toxic" property of protons. Comparison of the human experience with the monkey data indicates the RBE for induction of brain tumors to be about one. It is unlikely that protons cause an unusual change in oncogenic expression, as compared to conventional electromagnetic radiation.     

Radiation risk of the crew members of the expeditions on the "MIR" station during the 22nd solar activity cycle.

The radiation risk at the end of the flight was calculated for the members of the main expeditions on the "Mir" station. It was based on the absorbed dose dynamics data measured by the board dosimeter. The radiation damage models created for standards of the radiation safety of the space flights were used in the calculations. The analysis of the obtained values of the risk and its dynamics for some cosmonauts are presented in the topic. The risk values delta P are close to the limited levels given by equation of delta P = 0.6 x 10 x T(-4), [this equation appears also as delta RHrad = 0.6 x 10(-4) x T later in the text] where T--is flight duration in months.     

A demonstration of the potential of Cryosat-2 to contribute to mesoscale observation

Cryosat-2 was designed for its primary scientific objectives, i.e. for cryosphere science. As far as oceanography is concerned, various mission design choices make it less accurate than missions designed to comply with ocean surface topography requirements such as Jason-2 or ENVISAT. Cryosat-2-specific errors are equivalent to more than 50% of the sea surface height variability over 40% of the oceans. Cryosat-2’s sampling pattern is also suboptimal for mesoscale observation because the satellite tracks from any consecutive period of 2 to 20 days (e.g. the most recent and most valuable data for near real time mesoscale observation) are aggregated in 500 km wide bands which are interleaved with 500 km wide observation gaps.     

Improved predictions of equatorial TEC for real time applications

It is important to use models developed specifically for the equatorial ionospheric estimation for real-time applications, particularly in Satellite Navigation. This work demonstrates a methodology for improved predictions of VTEC in real time using the model developed for the equatorial ionosphere by the authors. This work has been done using TEC data of the low solar activity period of 2005 obtained using dual frequency GPS receivers installed under the GAGAN project of ISRO. For the purpose, the model is first used in conjunction with Kriging technique. Improvement in accuracy is observed when compared with the estimations from the model alone using the measurements as true reference. Further improvement is obtained by Bayesian combination of these estimates with independent Neural Network based predictions. Statistical performance of improvement is provided. An improvement of ∼1 m in confidence level of estimation of VTEC is obtained.     

工件表面轮廓均方根斜率的光散射测量

描述并确定具有明显纹理粗糙表面均方根斜率的光散射技术(均方根斜率是联合表面轮廓高度和波长特性的混合参数)。称为散射光锥法(The scattered light-conemethod)的该技术是基于激光角散射检测阵列(DALLAS——Defector Array for Laser LishtAngular Scattering),它用于测量粗糙表面散射光角分布的仪器。均方根斜率是从DALLAS光散射图象的角宽得到的。一般可以发现角宽(即估计的均方根斜率)对光的入射角和散射角变化相当大时是不敏感的。这些结果与表面材料无关,并且对正弦和随机粗糙表面都是有效的。介绍了散射光锥法的测量原理、实验、数据分析和几点结论。     

Energetic ion emission for active spacecraft control

Future space missions aiming at the accurate measurement of cold plasmas and DC to very low frequency electric fields will require that the potential of their conductive surfaces be actively controlled to be near the ambient plasma potential. In the near-Earth space these spacecraft are usually solar-cell powered; consequently, parts of their surface are most of the time exposed to solar photons. Outside the plasmasphere, a positive surface potential due the dominance of surface-emitted photoelectrons over ambient plasma electrons is to be expected. Photo- and ambient electrons largely determine the potential and positive values between a few Volts up to 100 V have been observed. Active ion emission is the obvious solution of this problem. A liquid metal ion emitter and a saddle field ion emitter are nearing the stage of flight unit fabrication. We will attempt to clamp the spacecraft potential to values close to the plasma potential. We present first results from vacuum chamber tests and describe the emission behaviour and characteristics of emitters producing, respectively, In⁺ and N₂⁺ beams with an energy of ≥ 5 keV.     

PAMELA observational capabilities of Jovian electrons

PAMELA is a satellite-borne experiment that has been launched on June 15th, 2006. It is designed to make long duration measurements of cosmic radiation over an extended energy range. Specifically, PAMELA is able to measure the cosmic ray antiproton and positron spectra over the largest energy range ever achieved and will search for antinuclei with unprecedented sensitivity. Furthermore, it will measure the light nuclear component of cosmic rays and investigate phenomena connected with solar and earth physics. The apparatus consists of: a time of flight system, a magnetic spectrometer, an electromagnetic imaging calorimeter, a shower tail catcher scintillator, a neutron detector and an anticoincidence system. In this work a study of the PAMELA capabilities to detect electrons is presented. The Jovian magnetosphere is a powerful accelerator of electrons up to several tens of MeV as observed at first by Pioneer 10 spacecraft (1973). The propagation of Jovian electrons to Earth is affected by modulation due to Corotating Interaction Regions (CIR). Their flux at Earth is, moreover, modulated because every 13 months Earth and Jupiter are aligned along the average direction of the Parker spiral of the Interplanetary Magnetic Field.PAMELA will be able to measure the high energy tail of the Jovian electrons in the energy range from 50 up to 130 MeV. Moreover, it will be possible to extract the Jovian component reaccelerated at the solar wind termination shock (above 130 MeV up to 2 GeV) from the galactic flux.     

Preparation of the Biochip experiment on the EXPOSE-R2 mission outside the International Space Station

Biochips might be suited for planetary exploration. Indeed, they present great potential for the search for biomarkers – molecules that are the sign of past or present life in space – thanks to their size (miniaturized devices) and sensitivity. Their detection principle is based on the recognition of a target molecule by affinity receptors fixed on a solid surface. Consequently, one of the main concerns when developing such a system is the behavior of the biological receptors in a space environment. In this paper, we describe the preparation of an experiment planned to be part of the EXPOSE-R2 mission, which will be conducted on the EXPOSE-R facility, outside the International Space Station (ISS), in order to study the resistance of biochip models to space constraints (especially cosmic radiation and thermal cycling). This experiment overcomes the limits of ground tests which do not reproduce exactly the space parameters. Indeed, contrary to ground experiments where constraints are applied individually and in a limited time, the biochip models on the ISS will be exposed to cumulated constraints during several months. Finally, this ISS experiment is a necessary step towards planetary exploration as it will help assessing whether a biochip can be used for future exploration missions.