Research on Biolab, a multi-user facility for APM

A study carried out by a team of seven scientists appointed by ESA resulted in the design of a biological laboratory "Biolab" for Columbus APM. The basis for the study were four pre-Phase A studies performed by industry on the assumption that 15 racks would be available to biology and biotechnology in the APM. Due to the constraints newly imposed by the Columbus project, only five racks are now allocated. The tasks of the Biolab scientific team were: (i) to define the scientific objectives of biological research in Columbus; (ii) to review the requirements of the industrial studies; and (iii) to design a multi-purpose facility compatible with the present constraints and satisfying the requirements of the biological investigations considered in the four studies. The Biolab team was able to define a facility capable of accommodating in five racks the following biological objects: small plants (up to 40 cm), insects like drosophila, frog eggs, single cells from animals, bacteria, slime molds and protozoa, as well as human physiology, but restricted to general diagnostic needs. The Biolab facility includes instruments and devices providing the capacity of holding and/or growing the organisms as well as to perform basic experimentation and a minimum essential diagnostic inflight. Within the growth unit the growth chambers/incubators are exchangeable, permitting the use of growth chambers of different sizes. The temperature will be adjustable to the requirements of the objects under investigation, i.e. either 20 or 37 degrees C. Thus a considerable level of flexibility will permit to investigate a broad spectrum of living systems.     

Submicron lunar ejecta in the magnetosphere associated with meteor showers

Recent studies of the lunar ejecta from lunar impacts of interplanetary dust particles indicate that during favorable lunar phases, over 80% of the submicron ejecta enters the earth's magnetosphere. This “pulse” of lunar ejecta produced by the sporadic meteor background will follow the random variations of the sporadic flux. An additional enhancement of this flux can be related to major meteor showers. Since the annual periods of these showers occur during varying lunar phase angles, magnetosphere ejecta flux associated with major showers will vary depending on the coincidence of shower periods and favorable lunar phase angles. The results of an analysis of the “pulse” of ejecta flux in the magnetosphere during the Quadrantids, Geminids, Leonids, and Perseids meteor showers are presented. These results are compared to the satellite measurements of 1959 Eta and HEOS II.     

Scientific results from the pioneer Saturn infrared radiometer

The Pioneer 11 Infrared Radiometer instrument made observations of Saturn and its rings in broadband channels centered at 20 and 45 μm and obtained whole-disk information on Titan. A planetary average effective temperature of 96.5±2.5 K implies a total emission 2.8 times the absorbed sunlight. Correlation with radio science results implies that the molar fraction of H₂ is 90±3% (assuming the rest is He). Temperatures at the 1 bar level are 137 to 140 K; regions appearing cooler may be overlain by a cloud acting as a 124 K blackbody surface. A minimum temperature averaging 87 K is reached near 0.06 bars. Ring boundaries and optical depths are consistent with those at optical wavelengths. Ring temperatures are 64–86 K on the south (illuminated) side, ～54 K on the north (unilluminated) side, and at least 67 K in Saturn's shadow. There is evidence for a south to north drop in ring temperatures. Titan's 45 μm brightness temperature is 75±5 K.     

ATE paperless multimedia information and data collection system

An overview is given of the Productivity, Reliability, Availability, and Maintainability (PRAM) Project 00-256, which aims to integrate the Digital Multimedia Information System (DMIS) into the Reconnaissance Module Automatic Test System (RMATS). Benefits to be derived from the incorporation of the DMIS and return on investment for the US Air Force are discussed. The process used to obtain approval and funding support for this advanced maintenance aiding and data collection system is described     

Extreme dryness and DNA-protein cross-links.

Exposure of fungal conidia (Aspergillus ochraceus) or spores of Bacillus subtilis to extreme dryness or vacuum induces DNA lesions, including strand breaks and the formation of DNA-protein cross-links. In wet cells only a small amount of protein is bound to DNA, but exposure to conditions of lowered water activity results in an increasing number of cross-links between DNA and proteins. In fungal conidia these cross-links are detected after selective iodination (125 J) of the DNA-bound proteins followed by gel electrophoresis and subsequent autoradiography. Another approach is the labelling of DNA with 32P by means of nick translation and the detection of differences in the electrophoretic mobility of DNA before and after digestion with proteinase K of proteins bound to DNA.     

Reduced lymphocyte activation in space: role of cell-substratum interactions.

We investigated the effect of substratum adhesiveness on stimulated lymphocyte blastogenesis by reducing and blocking cell adhesion with poly (2-hydroxyethyl methacrylate) (poly-HEMA) in a simple on-ground system. Cells grown on medium-thick and thick poly-HEMA films were rounded in shape and displayed no signs of spreading. By contrast, on tissue culture plastic and very thin poly-HEMA films, they showed clear signs of spreading. The mitogenic response of lymphocytes grown on thick poly-HEMA films was reduced by up to 68% of the control (tissue culture plastic). Interferon-gamma production was near zero when the cells were grown on the least adhesive substratum. On uncoated plastic, activated lymphocytes subjected to high gravity (20g) exhibited an increased proliferation rate (40%) compared with 1g. By contrast, on poly-HEMA, high gravity did not improve lymphocyte responsiveness. These results show that activated lymphocytes need to anchor and spread prior to achieving an optimal proliferation response. We conclude that decreased lymphocyte adhesion could contribute to the depressed in vitro lymphocyte responsiveness found in the microgravity conditions of space flight.     

The statistical properties of coronal mass ejections during 1979–1981

The Solwind coronagraph on the P78-1 earth-orbiting satellite has been monitoring the Sun routinely at 10-minute intervals during the 5-year interval from April, 1979 to the present. In a statistical analysis of about 1000 mass ejections observed through the end of 1981, we find an average occurrence rate of 1.8 mass ejections per day. Histograms of speed, central latitude, angular span, brightness, and other parameters have been constructed, and properties such as shape classification have been tabulated. These characteristics are summarized for these years near sunspot maximum. The average speed and mass estimate are found to be similar to those found at the declining phase of the previous sunspot cycle. The angular span and central latitude distributions are quite different than seen during the declining phase, and are very dependent upon structural class. The fluctuations in the occurrence rate of CMEs does not seem to match the fluctuations in the sunspot number. There is a tendency for high speed CMEs to occur more frequently in 1981 than in 1980, and more frequently in 1980 than in 1979.     

Embedded information system re-engineering

Currently fielded embedded information systems face readiness challenges imposed by evolving missions and extended service lifespans. The ability to overcome these challenges is constrained by such factors as shrinking budgets, limited computational capacity and diminished manufacturing sources effects that impact both hardware and software options. Wholesale redevelopment is often cost prohibitive, particularly since large portions of embedded applications continue to fulfil mission requirements. Solutions must preserve prior investments while providing efficient pathways for continued technology refresh. A technology solution for affordable modernization of legacy system software is being development. The Embedded Information System Re-engineering (EISR) project is developing an automation-assisted JOVIAL-to-C re-engineering capability that permits simultaneous modernization of both the structure and source language of legacy embedded applications. Engineers will be able to apply the proven labor-saving visualization and analysis features of modern CASE tools to legacy JOVIAL applications. EISR will thus allow the DoD to recapture previous investments in proven legacy algorithms and mission capabilities while permitting the full exploitation of COTS economies of scale. This paper describes in brief the goals and objectives of the EISR project, and provides the current status of the EISR capability.