Postmission plasma volume and red-cell mass changes in the crews of the first two Skylab missions

Red-cell mass determinations were performed before and after the first two Skylab missions. The data showed a 14% mean decrease in red-cell mass after the 28-day mission and a 12% mean decrease after the 59-day mission. The red-cell mass returned to premission levels more slowly after the shorter (28-day) than after the longer mission. Plasma volume decreases were found after each mission. with the crew from the longer mission showing the greater change (13% vs. 8.4%). Postmission decreases in red-cell mass and plasma volume have been a general finding in crewmen who return from short or long spaceflight.     

Equivalent Electric Circuit Models of Coronal Magnetic Loops and Related Oscillatory Phenomena on the Sun

Coronal loops, which trace closed magnetic field lines, are the primary structural elements of the solar atmosphere. Complex dynamics of solar coronal magnetic loops, together with action of possible subphotospheric dynamo mechanisms, turn the majority of the coronal loops into current-carrying structures. In that connection none of the loops can be considered as isolated from the surroundings. The current-carrying loops moving relative to each other interact via the magnetic field and currents. One of the ways to take into account this interaction consists in application of the equivalent electric circuit models of coronal loops. According to these models, each loop is considered as an equivalent electric LCR-circuit with variable inductive coefficients L, capacitance C, and resistance R, which depend on shape, scale, position of the loop with respect to neighbouring loops, as well as on the plasma parameters in the magnetic tube. Such an approach enables to describe the process of electric current dynamics in the groups of coronal loops, as well as the related dynamical, energy release and radiation processes. In the present paper we describe the major principles of LCR-circuit models of coronal magnetic loops, and show their application for interpretation of the observed oscillatory phenomena in the loops and in the related radiation.     

The Role and Contributions of Energetic Neutral Atom (ENA) Imaging in Magnetospheric Substorm Research

Energetic Neutral Atom (ENA) imaging has contributed substantially to substorm research. This technique has allowed significant advances in areas such as observation and quantification of injected particle drift as a function of energy, observation of dynamics in the tail that are directly related to the effects of imposed (growth phase) and induced (expansion phase) electric fields on the plasma, the prompt extraction of oxygen from the ionosphere during substorms, the relationship between storms and substorms, and the timing of substorm ENA signatures. We present discussion of the advantages and shortcomings of the ENA technique for studying space plasmas. Although the technique is in its infancy, it is yielding results that enrich our understanding of the substorm process and its effects.     

Effect of microgravity on Escherichia coli and MS-2 bacteriophage disinfection by iodinated resins

Experiments on chemical disinfection by iodinated resins were conducted on STS 50 (USML-1), which flew a 13 day mission during 1992. Fluid processing apparatus containing microorganisms and iodinated resins was assembled in either Manhattan, Kansas, or Boulder, Colorado, and loaded on-board the Space Shuttle for the mission. Pentaiodide resin was more effective than the triiodide resin against Escherichia coli. Both resins were more effective bactericides at unit gravity than microgravity because of cosedimentation of bacteria and iodinated resin beads. In bacteriophage experiments, the triiodide resin reduced the viable titer of MS-2 by nine logs. The few viable phage surviving chemical disinfection were associated with precipitant formation in the fluid processing apparatus.     

Molecular alterations in tumorigenic human bronchial and breast epithelial cells induced by high LET radiation.

Carcinogenesis is a multi-stage process with sequence of genetic events governing the phenotypic expression of a series of transformation steps leading to the development of metastatic cancer. In the present study, immortalized human bronchial (BEP2D) and breast (MCF-10F) cells were irradiated with graded doses of either 150 keV/micrometer alpha particles or 1 GeV/nucleon 56Fe ions. Transformed cells developed through a series of successive steps before becoming tumorigenic in nude mice. Cell fusion studies indicated that radiation-induced tumorigenic phenotype in BEP2D cells could be completely suppressed by fusion with non-tumorigenic BEP2D cells. The differential expressions of known genes between tumorigenic bronchial and breast cells induced by alpha particles and their respective control cultures were compared using cDNA expression array. Among the 11 genes identified to be differentially expressed in BEP2D cells, three (DCC, DNA-PK and p21(CIP1)) were shown to be consistently down-regulated by 2 to 4 fold in all the 5 tumor cell lines examined. In contrast, their expressions in the fusion cell lines were comparable to control BEP2D cells. Similarly, expression levels of a series of genes were found to be altered in a step-wise manner among tumorigenic MCF-10F cells. The results are highly suggestive that functional alterations of these genes may be causally related to the carcinogenic process.     

On adaptive multiband signal detection with the SMI algorithm

In a nonstationary and/or nonhomogeneous interference environment, an adaptive system for target detection may suffer a severe performance degradation due to the lack of a sufficient amount of data from which the system can learn (estimate) the statistics of the environment. The detection performance of an adaptive system, which employs a frequency diversity (multiband) signaling waveform and a multiband sample matrix inversion algorithm (SMI), is analyzed. By comparison with the corresponding single-band system under the chosen system constraint, it is shown that the multiband system can significantly outperform the single band when the amount of data available from a single frequency band is severely limited by the environment     

长征运载火箭飞行过程中二级游机提前或推迟关机问题的探讨

论述了具有小推力飞行段的长征运载火箭在飞行过程中二级游机提前或推迟关机的机理,明确给出了游机可能提前或推迟关机的时间范围,为以后的火箭飞行参数判定提供理论依据。     

Aspartic acid racemization and age-depth relationships for organic carbon in Siberian permafrost

We have analyzed the degree of racemization of aspartic acid in permafrost samples from Northern Siberia, an area from which microorganisms of apparent ages up to a few million years have previously been isolated and cultured. We find that the extent of aspartic acid racemization in permafrost cores increases very slowly up to an age of approximately 25,000 years (around 5 m in depth). The apparent temperature of racemization over the age range of 0-25,000 years, determined using measured aspartic acid racemization rate constants, is -19 degrees C. This apparent racemization temperature is significantly lower than the measured environmental temperature (-11 to -13 degrees C) and suggests active recycling of D-aspartic acid in Siberian permafrost up to an age of around 25,000 years. This indicates that permafrost organisms are capable of repairing some molecular damage incurred while in a "dormant" state over geologic time.     

Observations of diffuse galactic positron annihilation radiation

The Galactic plane was scanned nearly three times by the UCSD/MIT Hard X-Ray and Low Energy Gamma-Ray Experiment on HEAO-1 from August 1977 through September 1978. Its Medium Energy Detectors were of the NaI/CsI phoswich type and operated over the 100 keV to 2 MeV range, with a 17° FWHM field of view and a 9% energy resolution at 511 keV. Sky maps for each epoch of observation were constructed in several energy bands. After subtraction of known point sources, a component associated with the galactic plane remains, whose spectrum is consistent with a power law and a positron annihilation spectrum. In the 333 to 583 keV energy band the flux is concentrated within ±35° of the galactic center, and the ratio of flux/radian (anticenter) is high, with a 2σ lower limit of 13. The parameters of the galactic center region's annihilation spectrum are positronium fraction of 0.9±0.1 and 511 keV flux of (2.0±0.7)×10⁻³ photons/cm²-sec-rad.