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81.
The oncogenic potential of high-energy 56Fe particles (1 GeV/nucleon) accelerated with the Alternating Gradient Synchrotron at the Brookhaven National Laboratory was examined utilizing the mouse C3H 10T1/2 cell model. The dose-averaged LET for high-energy 56Fe is estimated to be 143 keV/μm with the exposure conditions used in this study. For 56Fe ions, the maximum relative biological effectiveness (RBEmax) values for cell survival and oncogenic transformation were 7.71 and 16.5 respectively. Compared to 150 keV/μm 4He nuclei, high-energy 56Fe nuclei were significantly less effective in cell killing and oncogenic induction. The prostaglandin E1 analog misoprostol, an effective oncoprotector of C3H 10T1/2 cells exposed to X rays, was evaluated for its potential as a radioprotector of oncogenic transformation with high-energy 56Fe. Exposure of cells to misoprostol did not alter 56Fe cytotoxicity or the rate of 56Fe-induced oncogenic transformation.  相似文献   
82.
Angular motion at atmospheric entry is studied in the paper for a spacecraft with a bi-harmonic moment characteristic. Special attention is given to the case when the spacecraft possesses two stable balanced positions, and, hence, it can oscillate in dense atmospheric layers in the ranges of small or large angles of attack. The averaged equations of spacecraft motion are derived, which allow one to increase the speed of calculations by several orders of magnitude. A real example is presented, which concerns a spacecraft specially designed for descending in the Martian atmosphere.  相似文献   
83.
    
The aim of the proposed Beagle 2 small lander for ESA's 2003 Mars Express mission is to search for organic material on and below the surface of Mars and to study the inorganic chemistry and mineralogy of the landing site. The lander will have a total mass of 60kg including entry, descent, and landing system. Experiments will be deployed on the surface using a robotic arm. It will use a mechanical mole and grinder to obtain samples from below the surface, under rocks, and inside rocks. Sample analysis by a mass spectrometer will include isotopic analysis. An optical microscope, an X-ray spectrometer and a Mossbauer spectrometer will conduct in-situ rock studies.  相似文献   
84.
    
We propose to study the radiation environment on board different flight vehicles: cosmos-type satellites, orbital stations, Space Shuttles and civil (sonic and supersonic) aircraft. These investigations will be carried out with single type of passive detector, namely, nuclear photoemulsions (NPE) with adjustable threshold of particle detection within broad range of linear energy transfer (LET) that is done by means of the technique of selective development of NPE exposed in space.

These investigations will allow one to determine:

• integral spectra of LET of charged particles of cosmic ray (CR) over a wide range from 2.0 to 5×104 MeV/cm in biological tissue;

• differential energy spectra of fast neutrons (1–20 MeV);

• estimation of absorbed and equivalent doses from charged and neutral component CR;

• charge and energy spectra of low energy nuclei (E≤100 MeV) with Z≥2 having in view the extreme hazard radiation to biological objects and microelectronic schemes taken on board inside and outside of these different flight vehicles with exposures from several days to several months.

The investigation of radiation environment on board the airplanes depending on the flight parameters will be conducted using emulsions of different sensitivity without any controlling of threshold sensitivity (Akopova et al., 1996). The proposed detector can be used in the joint experiments on the new International Cosmic Station “Alpha”.  相似文献   

85.
    
Beyond the magnetic influence of the Earth, the flux of galactic cosmic radiation (GCR) represents a radiological concern for long-term manned space missions. Current concepts of radiation quality and equivalent dose are inadequate for accurately specifying the relative biological \"efficiency\" of low doses of such heavily ionising radiations, based as they are on the single parameter of Linear Energy Transfer (LET). Such methods take no account of the mechanisms, nor of the highly inhomogeneous spatial structure, of energy deposition in radiation tracks. DNA damage in the cell nucleus, which ultimately leads to the death or transformation of the cell, is usually initiated by electrons liberated from surrounding molecules by the incident projectile ion. The characteristics of these emitted \"delta-rays\", dependent primarily upon the charge and velocity of the ion, are considered in relation to an idealised representation of the cellular environment. Theoretically calculated delta-ray energy spectra are multiplied by a series of weighting algorithms designed to represent the potential for DNA insult in this environment, both in terms of the quantity and quality of damage. By evaluating the resulting curves, and taking into account the energy spectra of heavy ions in space, a relative measure of the biological relevance of the most abundant GCR species is obtained, behind several shielding configurations. It is hoped that this method of assessing the radiation quality of galactic cosmic rays will be of value when considering the safety of long-term manned space missions.  相似文献   
86.
    
There were several cases when modulated electron beam had been injected from APEX satellite into an otherwise unmodified ionospheric plasma. The beams were formed from 2 μs pulses repeated at a rate of 40kHz. Injections took place in the altitude range 400–1100km over Europe. The onboard receiver connected to the dipole antenna swept the frequency interval 1–10 MHz in 1 sec. Due to a relatively narrow receiver bandwidth (15 kHz), moderate frequency step (50 kHz), slow changes of fn and fc (local electron plasma and gyro frequencies) fine structure of excited emissions was detected. In many cases, a very prominent doublet could be convincingly identified as a (fn,fu=sqrt(fn*fn+fc*fc)) band, with fn practically equal to the local plasma frequency in the unperturbed ionosphere. Determination of plasma frequency is of prime importance in analysis of complex structures composed from various harmonics fn,fc,fu. Complexity is manifested as coalescing of various harmonics with maxima shifted from nominal frequencies or splitting them into components due to mixing of local and propagation effects. Despite the existence of strong emissions on frequencies characteristic for the unperturbed ionosphere, very strong broadcasting transmissions are frequently cut off, even when the beam is directed upward. Most typical spectra are discussed.  相似文献   
87.
    
By using a Doppler Weather Radar (DWR) at Shriharikota (13.66°N & 80.23°E), an Artificial Neural Network (ANN) based technique is proposed to improve the accuracy of rain intensity estimation. Three spectral moments of a Doppler spectra are utilized as an input data to an ANN. Rain intensity, as measured by the tipping bucket rain gauges around the DWR station, are considered as a target values for the given inputs. Rain intensity as estimated by the developed ANN model is validated by the rain gauges measurements. With the help of a developed technique, reasonable improvement in the estimation of rain intensity is observed. By using the developed technique, root mean square error and bias are reduced in the range of 34–18% and 17–3% respectively, compared to ZR approach.  相似文献   
88.
    
An evident signature of a least studied quasi-90-day oscillation is found in the winds and tides in the MLT from an equatorial station, São João do Cariri (7.4°S, 36.5°W). The oscillation is found to appear mainly in certain intervals with small but appreciable seasonal (fourth harmonic of annual oscillation) contribution. The maximum amplitude of the oscillation is found to be around 10 m/s in the zonal wind. The enhancement peak of the oscillation exhibits downward movement indicating a plausible role of upward moving waves/tides in carrying its imprint from below to the MLT. Similar oscillation feature in the tropospheric zonal wind and ozone may imply its lower atmospheric origin as a component of the intraseasonal oscillation (ISO) that moves upward by modulating the tides. Subsequently, the propagating tides (mainly semidiurnal) are enhanced by the ozone in the stratosphere through absorption of solar UV radiation and finally manifest the oscillation in the MLT. Consistency of the present findings with the past investigations are observed in some aspects of the oscillation, whereas existing mismatches in others are believed to be due to geophysical variability depending on space and time among various locations on the globe.  相似文献   
89.
A correlative analysis has been made between cosmic ray intensity and solar activity (sunspot numbers) during high amplitude days for the period 1991–1995. The high amplitude days with the time of maximum in the corotational/azimuthal direction do not indicate any significant correlation with solar activity. The diurnal amplitude significantly remains constant and high (0.5%) during the entire period. Our observations suggest that the direction of the anisotropy of high amplitude anisotropic wave train events contribute significantly to the short-term behavior of the cosmic ray diurnal anisotropy. The correlation coefficient is found to remain positive during solar activity maximum for all the high amplitude anisotropic wave train events.  相似文献   
90.
    
During the years 2002 and 2003, three closed system experiments were carried out in the \"Laboratory Biosphere\" facility located in Santa Fe, New Mexico. The program involved experimentation of \"Hoyt\" Soy Beans, (experiment #1) USU Apogee Wheat (experiment #2) and TU-82-155 sweet potato (experiment #3) using a 5.37 m2 soil planting bed which was 30 cm deep. The soil texture, 40% clay, 31% sand and 28% silt (a clay loam), was collected from an organic farm in New Mexico to avoid chemical residues. Soil management practices involved minimal tillage, mulching, returning crop residues to the soil after each experiment and increasing soil biota by introducing worms, soil bacteria and mycorrhizae fungi. High soil pH of the original soil appeared to be a factor affecting the first two experiments. Hence, between experiments #2 and #3, the top 15 cm of the soil was amended using a mix of peat moss, green sand, humates and pumice to improve soil texture, lower soil pH and increase nutrient availability. This resulted in lowering the initial pH of 8.0-6.7 at the start of experiment #3. At the end of the experiment, the pH was 7.6. Soil nitrogen and phosphorus has been adequate, but some chlorosis was evident in the first two experiments. Aphid infestation was the only crop pest problem during the three experiments and was handled using an introduction of Hyppodamia convergens. Experimentation showed there were environmental differences even in this 1200 cubic foot ecological system facility, such as temperature and humidity gradients because of ventilation and airflow patterns which resulted in consequent variations in plant growth and yield. Additional humidifiers were added to counteract low humidity and helped optimize conditions for the sweet potato experiment. The experience and information gained from these experiments are being applied to the future design of the Mars On Earth(R) facility (Silverstone et al., Development and research program for a soil-based bioregenerative agriculture system to feed a four person crew at a Mars base, Advances in Space Research 31(1) (2003) 69-75; Allen and Alling, The design approach for Mars On Earth(R), a biospheric closed system testing facility for long-term space habitation, American Institute of Aeronautics and Astronautics Inc., IAC-02-IAA.8.2.02, 2002).  相似文献   
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