Comparison of the roles of nucleotide synthesis, polymerization, and recombination in the origin of autocatalytic sets of RNAs

Ribozymes that act as polymerases and nucleotide synthases are known experimentally, even though no fully self-replicating system has yet been found. If the RNA World hypothesis is true, ribozymes must have arisen initially from within a random abiotic polymerization system. To investigate the origin of the RNA world, we studied a mathematical model of a chemical reaction system describing RNA polymerization. It is supposed that, in absence of ribozymes, polymerization occurs at a small spontaneous rate, and that in the presence of polymerase ribozymes, polymerization occurs at a faster rate that is proportional to the ribozyme concentration. Chains must be longer than a minimum threshold length in order to have the possibility of acting as ribozymes. The reaction system has two stable states that we term dead and living. The dead state is controlled by the small spontaneous rate and has negligible concentration of ribozymes. The living state has high concentration of ribozymes, and the reaction rates are determined by the ribozymes; thus, the system is autocatalytic. Concentration fluctuations in a finite volume can cause a transition to occur from the dead to the living state, that is, an origin of life occurs within this model. We also consider ribozymes that catalyze nucleotide synthesis. We show that living and dead states arise in the presence of synthase ribozymes in the same way as for polymerases. It has been proposed that recombination reactions are a way of generating long RNA chains in the early stages of life. We show that if the possibility of random reversible recombination reactions is added to our model, this does not lead to an increase in long polymer concentration. Thus, if recombination is fully reversible, there is no autocatalytic state controlled by recombination. Nevertheless, recombination can play an important role in ribozyme synthesis if there is an additional process that keeps the recombination reactions out of equilibrium. We modeled a case studied experimentally in which building block strands of moderate length associate due to RNA secondary structure formation. A recombination reaction then occurs between these strands to form a longer sequence that catalyzes its own formation via the recombination reaction. This system has an autocatalytic state, and it is possible for it to arise within our random polymerization system. If complexes formed by associations of shorter strands can act as catalysts without the requirement that the strands be covalently linked, this would alleviate the need for synthesis of very long strands; hence, it makes the emergence of an autocatalytic system from an abiotic random polymerization system much more likely.     

Broad band X-ray properties of GRO J1948+32/KS 1947+300

We present here results obtained from three BeppoSAX observations of the transient X-ray pulsar GRO J1948+32 carried out during the declining phase of its 2000 November–2001 June outburst. Timing analysis of the data clearly shows a 18.7 s pulsation in the X-ray light curves in 0.1–100 keV energy band. The pulse profile of GRO 1948+32 is characterized by a broad peak with a sharp rise followed by a narrow dip. The dip in the pulse profile shows very strong energy dependence. Phase-averaged spectroscopy obtained with three of the BeppoSAX instruments shows that the 0.1–100 keV energy spectrum is described by a Comptonized component, a weak blackbody component (7% of the total emission) for soft X-rays, a narrow and weak iron emission line at 6.7 keV and low column density of material in the line of sight. The results obtained from the analysis are discussed in this paper.     

Current legal issues pertaining to space solar power systems

This paper discusses a range of legal issues that need to be considered in planning for a space solar power system. Because objects placed in space are inherently international, the paper primarily looks at international law that affects launching, construction, operation, property rights, the environment, communication and liability. International coordination early in the planning process is urged to make space solar powers systems a reality more speedily.     

Smart Sensor Web: Web-based exploitation of sensor fusion forvisualization of the tactical battlefield

Smart Sensor Web (SSW) is a recent DUSD (S&T) initiative inspired by extraordinary technological advances in sensors and microelectronics and by the emergence of the Internet as a real time communication tool. The overall vision for SSW is an intelligent, Web-centric distribution and fusion of sensor information that provides greatly enhanced situational awareness, on demand, to warfighters at lower echelons. Emphasis is on multi-sensor fusion of large arrays of local sensors, joined with other assets, to provide real-time imagery, weather, targeting information, mission planning, and simulations for military operations on land, sea, and air. This paper gives an overview of this new initiative, highlights some of the technology challenges in sensor/information Fusion, and presents a program approach for near-term demonstrations and long-term solutions, involving the DoD, National Labs, commercial industry, and academia     

The LISA Pathfinder Mission

LISA Pathfinder, formerly known as SMART-2, is the second of the European Space Agency’s Small Missions for Advance Research and Technology, and is designed to pave the way for the joint ESA/NASA Laser Interferometer Space Antenna (LISA) mission, by testing the core assumption of gravitational wave detection and general relativity: that free particles follow geodesics. The new technologies to be demonstrated in a space environment include: inertial sensors, high precision laser interferometry to free floating mirrors, and micro-Newton proportional thrusters. LISA Pathfinder will be launched on a dedicated launch vehicle in late 2011 into a low Earth orbit. By a transfer trajectory, the sciencecraft will enter its final orbit around the first Sun-Earth Lagrange point. First science results are expected approximately 3 months thereafter. Here, we give an overview of the mission including the technologies being demonstrated.     

飞机腹舱的检查维修

货舱和行李舱所受的磨损程度仅次于机轮和刹车装置。这是因为在货物装卸过程中,货舱及行李舱受到日复一日的损坏。货舱和行李舱也是腐蚀最多的部位,而且在飞机进行大修检查前是无法察觉的。     

民用直升机MRO市场减速慢行

在金融危机发生之前,航空战略咨询公司曾预计2009年国际直升机MRO市场的增长速度是3%,达到56亿美元.但考虑到目前的经济状况,2009年民用直升机的MRO市场会比2008年减少5%～10%.这主要是因为直升机的使用率在下降,以及金融危机爆发之前高企的油价所致.(本文所指的民用直升机还包括经过特殊改装后的军用和准军用直升机,但不包括武装直升机.)     

A review of observed variability in the dayside ionosphere of Mars

Recent measurements by Mars Global Surveyor and Mars Express have greatly increased the number of observations of the martian dayside ionosphere available for study. Together with earlier measurements from the Viking era, these datasets have been used to investigate variations in well-known properties of the martian dayside ionosphere and to discover new ionospheric features. The dayside ionosphere includes the main peak, called the M2 layer, and a lower layer, called the M1 layer. In the topside, above the M2 layer, electron densities exponentially decrease with increasing altitude.