Changes in gravitational force induce alterations in gene expression that can be monitored in the live, developing zebrafish heart.

Little is known about the effect of microgravity on gene expression, particularly in vivo during embryonic development. Using transgenic zebrafish that express the gfp gene under the influence of a beta-actin promoter, we examined the affect of simulated-microgravity on GFP expression in the heart. Zebrafish embryos, at the 18-20 somite-stage, were exposed to simulated-microgravity for 24 hours. The intensity of GFP fluorescence associated with the heart was then determined using fluorescence microscopy. Our measurements indicated that simulated-microgravity induced a 23.9% increase in GFP-associated fluorescence in the heart. In contrast, the caudal notochord showed a 17.5% increase and the embryo as a whole showed only an 8.5% increase in GFP-associated fluorescence. This suggests that there are specific effects on the heart causing the more dramatic increase. These studies indicate that microgravity can influence gene expression and demonstrate the usefulness of this in vivo model of 'reporter-gene' expression for studying the effects of microgravity.     

Microgravity particle research on the space station: the Gas-Grain Simulation Facility.

In the gravitational field on Earth, the large settling rate of micron-sized particles and the effects of gravity-induced convection prohibit many interesting studies of phenomena such as coagulation, collisions, and mutual interactions of droplets, dust grains and other particles. Examples of exobiology experiments involving these phenomena are the simulation of organic aerosol formation in Titan's atmosphere, studies of the role of comets in prebiotic chemical evolution, and simulations of carbon grain interactions in various astrophysical environments. The Gas-Grain Simulation Facility (GGSF) is a proposed Earth-orbital laboratory that will allow present ground-based experimental programs which study processes involving small particles and weak interactions to be extended to a new domain. Physics issues that scientists wishing to propose GGSF experiments must consider are reviewed in this paper. Specifically, coagulation, motion in gases and vacua, and wall deposition of particles in a microgravity environment are discussed.     

Defense Meteorological Satellite Program

The DMSP is a total satellite system composed of spacecraft with meteorological sensors, an earthbased command and control network, fixed and mobile user stations, and a communication network linking the various segments together.     

Navigating towards the future: transitioning from terrestrial radio navigation to satellite navigation and airborne surveillance

This paper presents a proposal for transitioning from terrestrial-based navigation aids to implementing satellite and airborne surveillance as the primary navigation means. The transition occurs through several steps. First, the installation and use of modern navigation and surveillance equipment is mandated by the regulatory organizations. The installations should take place in a sequenced fashion to allow time for companies to absorb the initial cost. Next, the existing network of terrestrial navigation aids is down-sized leaving only the areas of heaviest use in service. At this point, the global positioning system (GPS) will be deemed the primary method of terrestrial and oceanic travel. Finally, terrestrial navigation stations will be available around airports and the remaining stations will be put in a standby condition for use in the event of a national emergency. This paper will discuss the security benefits and examples of cost savings through implementation of these steps.     

Minimizing human-machine interface failures in high risk systems

Technology now permits the building of very complex man-machine systems with centralized controls, with the result that many processes can be run by relatively few individual workers. Studies of failures within these complex systems indicate that they are usually the consequence of a series of highly complex coincidences. There is an institutional neglect or misunderstanding of the implications of low-probability, high-consequence events for the design of complex man-machine systems. We must stop designing systems in which we virtually guarantee that operator errors will occur with catastrophic consequences. The greatest payback in reducing high risk system accidents is to reduce catastrophes induced or exacerbated by human error. This paper discusses some task breakdowns between the human element and software/hardware. These task allocations allow the complex man-machine system to be designed more robustly and prevent human error so as to reduce possible catastrophic consequences     

A root moisture sensor for plants in microgravity.

Development of components for bioregenerative life-support systems is a vital step toward long-term space exploration. The culturing of plants in a microgravity environment may be optimized by the use of appropriate sensors and controllers. This paper describes a sensor developed for determining the amount of fluid (nutrient solution) available on the surface of a porous ceramic nutrient delivery substrate to the roots of conventional crop plants. The sensor is based on the change in thermal capacitance and thermal conductance near the surface as the moisture content changes. The sensor could be employed as a data acquisition and control sensor to support the automated monitoring of plants grown in a microgravity environment.     

Measurements of electrical breakdown in the vicinity of a sounding rocket differentially charged to 10 kV

During the initial period of high voltage biasing of the SPEAR-3 sounding rocket payload, it was observed that electrical breakdown occurred in the gas surrounding the rocket. The breakdown occurred almost all the way to apogee of 289 km on the upleg, but did not recur on the downleg until the payload reached an altitude of 100 km. It is suggested that this behavior can be attributed to payload outgassing on the upleg leading to abnormally high gas pressure near the payload skin. Consideration of a modified Paschen discharge process with varying pressure along the discharge path was found to be consistent with the results.     

Monitoring power supply current and using a neural network routineto diagnose circuit faults

As a circuit is tested, the current drawn from a power supply can vary as different functions are invoked by the test. The current draw can be plotted against time, showing a characteristic trace for the test performed. Sensors in the ATS power supply can be used to monitor the current flow during test execution. Defective components can be classified using a Neural Network according to the pattern of variation from the “trace” of a good card. This can be performed as a background function, with the network gaining in accuracy over time. This paper discusses the Neural Network Routine for diagnosing circuit faults using monitored power supply current