Effects of microgravity on c-fos gene expression in osteoblast-like MC3T3-E1 cells.

The paper summarizes the data on proliferation and gravity-related gene expression of osteoblasts that were obtained from an experiment conducted under simulated and real microgravity conditions. Simulated microgravity conditions obtained in a clinostat depress proliferation of both osteoblast-like MC3T3-E1 and HeLa carcinoma cells. This depression of proliferation occurs in a collagen gel culture in which the flow of culture medium by rotation may be reduced. Interestingly, MC3T3-E1 cells which are probably one of target cells to microgravity are more sensitive than the HeLa cells. Simulated microgravity inhibited the epidermal growth factor (EGF)-induced c-fos gene expression in the MC3T3-El cells. To examine in detail the effect of real microgravity on the EGF signal transduction cascade in osteoblasts, MC3T3-E1 cells were cultured in the Cell Culture Experiment Module of the sounding rocket TR-1A6. The EGF-induced c-fos expression in cells was depressed under short-term microgravity conditions in the sounding rocket, while the phosphorylation of mitogen-activated protein kinase (MAPK) was not affected compared with the controls grown on the ground. These results suggest that an action site of microgravity in the signal transduction pathway may be downstream of MAPK.     

Galileo Photopolarimeter/Radiometer experiment

The Photopolarimeter/Radiometer (PPR) is a remote sensing instrument on the Galileo Orbiter designed to measure the degree of linear polarization and the intensity of reflected sunlight in ten spectral channels between 410 and 945 nm to determine the physical properties of Jovian clouds and aerosols, and to characterize the texture and microstructure of satellite surfaces. The PPR also measures thermal radiation in five spectral bands between 15 and 100 m to sense the upper tropospheric temperature structure. Two additional channels which measure spectrally integrated solar and solar plus thermal radiation are used to determine the planetary radiation budget components. The PPR photopolarimetric measurements utilize previously flown technology for high-precision polarimetry using a calcite Wollaston prism and two silicon photodiodes to enable simultaneous detection of the two orthogonal polarization components. The PPR radiometry measurements are made with a lithium tantalate pyroelectric detector utilizing a unique arrangement of radiometric stops and a scene/space chopper blade to enable a warm instrument to sense accurately the much colder scene temperatures.     

Application of Gram-Schmidt algorithm to fully adaptive arrays

The Gram-Schmidt orthogonalization (GSO) algorithm has excellent numerical performance and is readily applicable to systolic implementations such as in a field of adaptive cancellation systems. A modified GSO algorithm for a fully adaptive array is proposed and computer simulations show that the proposed algorithm gives superior performance. A systolic implementation of the proposed GSO algorithm for fully adaptive array is presented. A feedback mode GSO algorithm for use with analog weights is also presented and has been shown to have excellent performance in the presence of weight errors     

SWE,a comprehensive plasma instrument for the WIND spacecraft

The Solar Wind Experiment (SWE) on the WIND spacecraft is a comprehensive, integrated set of sensors which is designed to investigate outstanding problems in solar wind physics. It consists of two Faraday cup (FC) sensors; a vector electron and ion spectrometer (VEIS); a strahl sensor, which is especially configured to study the electron strahl close to the magnetic field direction; and an on-board calibration system. The energy/charge range of the Faraday cups is 150 V to 8 kV, and that of the VEIS is 7 V to 24.8 kV. The time resolution depends on the operational mode used, but can be of the order of a few seconds for 3-D measurements. Key parameters which broadly characterize the solar wind positive ion velocity distribution function will be made available rapidly from the GGS Central Data Handling Facility.     

Radiative and hybrid cooling of infrared space telescopes

The designs of cold space telescopes, cryogenic and radiatively cooled, are similar in most elements and both benefit from orbits distant from the Earth. In particular such orbits allow the anti-sunward side of radiatively-cooled spacecraft to be used to provide large cooling radiators for the individual radiation shields. Designs incorporating these features have predictedT _tel near 20 K. The attainability of such temperatures is supported by limited practical experience (IRAS, COBE). Supplementary cooling systems (cryogens, mechanical coolers) can be advantageously combined with radiative cooling in hybrid designs to provide robustness against deterioration and yet lower temperatures for detectors, instruments, and even the whole telescope. The possibility of such major additional gains is illustrated by the Very Cold Telescope option under study forEdison, which should offerT _tel5 K for a little extra mechanical cooling capacity.     

Communications and radio determination system using twogeostationary satellites. I. System and experiments

We developed two types of hybrid terminals that can provide both satellite communication and position determination services in one system. One terminal uses the single channel per carrier (SCPC) technique and the other uses the spread spectrum (SS) technique. To evaluate the performance of the two systems, we carried out experiments in Japan and in the Pacific Ocean using two geostationary satellites, ETS-V (150°E) and Inmarsat (180°E). The ranging accuracy between the mobile terminals and the base station via the satellites was found to be about 200 m using the SCPC system and about 10 m using the SS system. The measured positioning accuracy was about 1 km in the SCPC system and about 600 m in the SS system when experiments were carried out near Japan. The experimental results show that the positioning errors were mainly caused by the orbital determination errors of the two satellites. Presented here are the configurations and features of the SCPC and SS terminals, the experimental system, and the experimental results     

Robust algorithm for combating look direction error problems

A simple and fast zero tracking algorithm for adaptive arrays with large look direction errors is presented and investigated. Basically, the algorithm is based on adjusting the complex zeroes of a power inversion array in a time-multiplexed manner to track all the sources in the environment. To preserve the desired signal which is supposed to be closest to the look direction of 0°, the algorithm removes the zero with the shortest distance to e^j0 so that the directional response consists of only nulls steered at the jammers. When compared with the least mean square (LMS) algorithm employing zeroth and first-order look direction constraints, the new algorithm has about the same implementation complexity, is considerably faster, and possesses a much better signal-to-noise ratio (SNR) performance when the look direction is erroneous     

Neural controllers for systems with unknown dynamics

This study presents a methodology for specifying a neural controller for a system about which no a priori model information is available. The neural design presumes that a finite duration input/output (I/O) histogram on the system is available. The design procedure extracts from the histogram sufficient information to specify the neural feedback controller. The resultant controller will drive the system along a general output reference profile (unknown during the design). The resultant controller also exhibits the capability of disturbance rejection and the capacity to stabilize unstable plants     

Characteristics of Icy Surfaces

The surfaces of the Solar System’s icy satellites show an extraordinary variety of morphological features, which bear witness to exchange processes between the surface and subsurface. In this paper we review the characteristics of surface features on the moons of Jupiter, Saturn, Uranus and Neptune. Using data from spacecraft missions, we discuss the detailed morphology, size, and topography of cryovolcanic, tectonic, aeolian, fluvial, and impact features of both large moons and smaller satellites.