Detection of microlesions induced by heavy ions using liposomes filled with fluorescent dye.

In cells irradiation by heavy ions has been hypothesized to produce microlesions, regions of local damage. In cell membranes this damage is thought to manifest itself in the form of holes. The primary evidence for microlesions comes from morphological studies of cell membranes, but this evidence is still controversial, especially since holes also have been observed in membranes of normal, nonirradiated, cells. However, it is possible that damage not associated with histologically discernable disruptions may still occur. In order to resolve this issue, we developed a system for detecting microlesions based on liposomes filled with fluorescent dye. We hypothesized that if microlesions form in these liposomes as the result of irradiation, then the entrapped dye will leak out into the surrounding medium in a measurable way. Polypropylene vials containing suspensions of vesicles composed of either dipalmitoyl phosphatidylcholine, or a combination of egg phosphatidylcholine and cholesterol were irradiated at the Brookhaven National Laboratory using 56Fe ions at 1 GeV/amu. In several cases we obtained a significant loss of the entrapped dye above the background level. Our results suggest that holes may form in liposomes as the result of heavy ion irradiation, and that these holes are large enough to allow leakage of cell internal contents that are at least as large as a 1 nm diameter calcein molecule.     

称重传感器的一种新的滞后补偿方法(英文)

通过对电阻应变式称重传感器在各种加载卸载情况下的滞后特性的分析 ,建立了其相应的数学模型 ,并初步探讨了一种可以通过程序在仪表中对传感器的重要指标—滞后进行补偿从而提高整个传感器的精度的方法。最后 ,对以上方法进行了验证性试验 ,证明了补偿方法的可行性。     

Differential flank growth.

With the mathematical basis for the precise analysis of developmental processes in plants, the patterns of growth in phototropic and gravitropic responses have become better understood. A detailed temporal and spatial quantification of a growth process is an important tool for evaluating hypotheses about the underlying physiological mechanisms. Studies of growth rates and curvature show that the original Cholodny-Went hypothesis cannot explain the complex growth patterns during tropic responses of shoots and roots. In addition, regulating factors other than the lateral redistribution of hormones must be taken into account. Electrophysiological studies on roots led to a modification of the Cholodny-Went hypothesis in that redistributions of bioelectrical activities are observed.     

The Electron Beam Instrument (F6) on Freja

The Electron Beam Instrument (F6) onFreja is the first attempt to apply the electron drift technique in a region of large ambient magnetic fields. The paper describes the operational principles, the technical realization, and the difficulties encountered in the derivation of the electric fields.     

Field formation around negatively biased solar arrays in the LEO-plasma

Heavy emission caused by impacting plasma ions results in a fast discharging effect of the initially large surface potentials on the dielectric solar cells. This eventually counteracts the energization process of the plasma ions to the cover glasses and leaves no significant electric fields. Thus, with an existing thermal plasma, electrons are again able to reach dielectric surfaces. Strong localized electric fields of the order of several 10 kV/cm form near the interconnector-cover glass interface.     

Circumstellar chemistry from microwave and mm-wave spectroscopy.

Stars in their late stages of evolution often shed matter in the form of a cool wind which is molecular in composition. These winds are a major source of replenishment of the interstellar gas and dust, so they furnish a large part of the raw materials for new generations of stars and planets. The chemistry of the circumstellar envelope depends strongly on the photospheric abundances of the elements, especially C and O. If C/O > 1, a rich organic chemistry is observable in the microwave and mm-wavelength emission lines of the reactions products. This paper reviews the observational evidence for the presence of organic molecules and their formation pathways in circumstellar envelopes, with special emphasis on rotational spectra at microwave and millimeter wavelengths.     

The INFRARED SPACE OBSERVATORY (ISO)

The INFRARED SPACE OBSERVATORY (ISO), a project of the European Space Agency (ESA), will make various astronomical observations in the wavelength range of 2 to 200 μm. Two-thirds of its observing time will be available to guest observers via the traditional route of proposal submission. ISO will be launched in 1995 by an Ariane 4 from Kourou (Guyana) and be brought into a very elongated orbit with a 24hr period of which 16 hr can be used for astronomical observations. The payload module is essentially a large cryostat with a tank that will be filled with over 2000 litres of superfluid helium to keep the instruments cold (2 to 4 K) during an expected lifetime of 18 months. Inside the dewar, there is a Ritchey-Chretien telescope with a primary mirror of diameter 60cm. Four instruments, each provided by a different PI consortium, share the ISO focal plane. These instruments are : a photometer, a camera and two spectrometers — one for the wavelength range 2–45 μm and the other for 45–180 μm.     

Observer-type Kalman innovation filter for uncertain linear systems

An observer-type of Kalman innovation filtering algorithm to find a practically implementable "best" Kalman filter, and such an algorithm based on the evolutionary programming (EP) optima-search technique, are proposed, for linear discrete-time systems with time-invariant unknown-but-hounded plant and noise uncertainties. The worst-case parameter set from the stochastic uncertain system represented by the interval form with respect to the implemented "best" filter is also found in this work for demonstrating the effectiveness of the proposed filtering scheme. The new EP-based algorithm utilizes the global optima-searching capability of EP to find the optimal Kalman filter and state estimates at every iteration, which include both the best possible worst case Interval and the optimal nominal trajectory of the Kalman filtering estimates of the system state vectors. Simulation results are included to show that the new algorithm yields more accurate estimates and is less conservative as compared with other related robust filtering schemes     

Extracting multiple frequencies from phase-only data

The problem of extracting multiple frequencies from phase-only data is addressed. Multiple frequency estimation is accomplished by reconstructing the Fourier transform of the complex-valued time signal and then finding peaks in the frequency domain. We present a set of conditions under which a discrete-time complex sequence can be completely specified by its phase-only information. Two candidate multiple frequency estimation schemes are introduced, one based on a closed-form least-squares inverse, the other an iterative reconstruction algorithm. The uniqueness of the closed-form solution and the convergence of the iterative scheme have been proven under certain conditions. Several examples are given, including the case where the phase is quantized as would happen in an analog-to-digital (A/D) converter. Extensions to the multidimensional case, and to the case of real-part only reconstruction are straightforward.