Changes of deoxyribonucleoprotein in the spleen, thymus and liver of rats exposed to weightlessness and artificial gravity aboard the Cosmos biosatellites

Changes of deoxyribonucleoprotein in the spleen, thymus and liver of rats exposed to wegithlessness or artifical gravity on board biosatellites Cosmos 782 and Cosmos 936 after 20 days of flight were investigated. The level of polydeoxyribonucleotides in the spleen and thymus of rats exposed during the flight to weightlessness increased 4 – 11 hours after landing, suggesting breakdown of a part of the deoxyribonucleoprotein present. The use of artifical gravity prevented this breakdown in the thymus but not in the spleen. The breakdown was accompanied in the majority of cases by a decrease in teh deoxyribonucleoprotein content. We believe the breakdown of deoxyribonucleoprotein is due to a nonspecific stress reaction to the change from the weightless state to that of terrestrial gravity during landing. The polydeoxyribonucleotide level and amount of deoxyribonucleoprotein in the majority of cases returned to normal values during the 25 days of readaptation. No substantial change of deoxyribonucleoprotein was found in the liver. The different findings in the three organs are due to the fact that breakdown of deoxyribonucleoprotein takes place in sensitive cells underlying pycnosis. These cells are found in the spleen and thymus, but not in the liver.     

Low fluence.

The question of the appropriate extrapolation to low dose has long been a subject of controversy. A linear no-threshold model is favored by regulatory bodies as the basis of RBE assignments and estimates of radiation hazards to the general population. This model is largely supported by extensive application of the linear-quadratic survival formula "fitted" statistically to a wide variety of experimental data obtained at doses typically exceeding 1 Gy, and then extrapolated to mGy for practical applications, and even to the prediction of hazards from single electrons. Such extrapolations are questionable at best, and may even prove hazardous for risk evaluations. Fluence and geometry rather than dose based data are proposed as a basis for a limiting "threshold" for a "low dose" extrapolation. The proposed threshold is one where the fluence of particles is one per square micron, where on average only 2/3 of the 1 micrometers2 pixels covering an irradiated area are traversed by one or more particles. The corresponding dose threshold is determined by the LET of the bombarding radiation. For relativistic electrons this dose is about 0.032 Gy.     

Does mental arithmetic before head up tilt have an effect on the orthostatic cardiovascular and hormonal responses?

Passive head up tilt (HUT) and mental arithmetic (MA) are commonly used for providing mental and orthostatic challenges, respectively. In animal experiments, even a single exposure to a stressor has been shown to modify the response to subsequent stress stimulus. We investigated whether MA applied before HUT elicits synergistic responses in orthostatic heart rate (HR), cardiac output (CO), heart rate variability and arterial blood pressure. The 15 healthy young males were subjected to two randomized protocols: (a) HUT and (b) HUT preceded by MA, with sessions randomized and ≥2 weeks apart. Beat to beat continuous hemodynamic variables were measured and saliva samples taken for hormonal assay. HUT alone increased HR from 59±7 (baseline) to 80±10 bpm (mean±SD) and mean blood pressure (MBP) from 88±10 to 91±14 mmHg. HUT results after MA were not different from those with HUT alone. The activity of alpha amylase showed differences during the experiments irrespective of the protocols. We conclude that mental challenge does not affect orthostatic cardiovascular responses when applied before; the timing of mental loading seems to be critical if it is intended to alter cardiovascular responses to upright standing.     

The effects of the solar magnetic polarity and the solar wind velocity on Bz-component of the interplanetary magnetic field

We have studied the effect of both solar magnetic polarity and the solar wind velocity on the Bz-component of the interplanetary magnetic field, IMFBz, for the minimum activity of the solar cycles 21, 22, 23 and 24. We made a statistical study of IMFBz in the first section which is considered as an extension of Lyatsky et al. (2003). They made a statistical study of IMFBz for two periods of minimum solar activity 22 and 23 related to 1985–1987 and 1995–1997 when the solar magnetic field had opposite polarity. Our results seem to be consistent with the results obtained by Lyatsky et al. (2003). We found that there is a dependence of IMFBz on the IMFBx and the solar magnetic polarity for the minimum periods of the selected four solar cycles. In addition, we found that there is a dependence of IMFBz on the solar wind velocity.     

The Plasma and Suprathermal Ion Composition (PLASTIC) Investigation on the STEREO Observatories

The Plasma and Suprathermal Ion Composition (PLASTIC) investigation provides the in situ solar wind and low energy heliospheric ion measurements for the NASA Solar Terrestrial Relations Observatory Mission, which consists of two spacecraft (STEREO-A, STEREO-B). PLASTIC-A and PLASTIC-B are identical. Each PLASTIC is a time-of-flight/energy mass spectrometer designed to determine the elemental composition, ionic charge states, and bulk flow parameters of major solar wind ions in the mass range from hydrogen to iron. PLASTIC has nearly complete angular coverage in the ecliptic plane and an energy range from ～0.3 to 80 keV/e, from which the distribution functions of suprathermal ions, including those ions created in pick-up and local shock acceleration processes, are also provided.     

The Hydrogen Exospheric Density Profile Measured with ASPERA-3/NPD

We have evaluated the Lyman-α limb emission from the exospheric hydrogen of Mars measured by the neutral particle detector of the ASPERA-3 instrument on Mars Express in 2004 at low solar activity (solar activity index = 42, F_10.7=100). We derive estimates for the hydrogen exobase density, n _H = 10¹⁰ m^?3, and for the apparent temperature, T > 600 K. We conclude that the limb emission measurement is dominated by a hydrogen component that is considerably hotter than the bulk temperature at the exobase. The derived values for the exosphere density and temperature are compared with similar measurements done by the Mariner space probes in the 1969. The values found with Mars Express and Mariner data are brought in a broader context of exosphere models including the possibility of having two hydrogen components in the Martian exosphere. The present observation of the Martian hydrogen exosphere is the first one at high altitudes during low solar activity, and shows that for low solar activity exospheric densities are not higher than for high solar activity.     

Regolith X-Ray Imaging Spectrometer (REXIS) Aboard the OSIRIS-REx Asteroid Sample Return Mission

The Regolith X-ray Imaging Spectrometer (REXIS) is the student collaboration experiment proposed and built by an MIT-Harvard team, launched aboard NASA’s OSIRIS-REx asteroid sample return mission. REXIS complements the scientific investigations of other OSIRIS-REx instruments by determining the relative abundances of key elements present on the asteroid’s surface by measuring the X-ray fluorescence spectrum (stimulated by the natural solar X-ray flux) over the range of energies 0.5 to 7 keV. REXIS consists of two components: a main imaging spectrometer with a coded aperture mask and a separate solar X-ray monitor to account for the Sun’s variability. In addition to element abundance ratios (relative to Si) pinpointing the asteroid’s most likely meteorite association, REXIS also maps elemental abundance variability across the asteroid’s surface using the asteroid’s rotation as well as the spacecraft’s orbital motion. Image reconstruction at the highest resolution is facilitated by the coded aperture mask. Through this operation, REXIS will be the first application of X-ray coded aperture imaging to planetary surface mapping, making this student-built instrument a pathfinder toward future planetary exploration. To date, 60 students at the undergraduate and graduate levels have been involved with the REXIS project, with the hands-on experience translating to a dozen Master’s and Ph.D. theses and other student publications.     

Ionospheric response of equatorial and low latitude F-region during the intense geomagnetic storm on 24–25 August 2005

In this investigation, we present and discuss the response of the ionospheric F-region in the South American and East Asian sectors during an intense geomagnetic storm in August 2005. The geomagnetic storm studied reached a minimum Dst of −216 nT at 12:00 UT on 24 August. In this work ionospheric sounding data obtained of 24, 25, and 26 August 2005 at Palmas (PAL; 10.2° S, 48.2° W; dip latitude 6.6° S), São José dos Campos (SJC, 23.2° S, 45.9° W; dip latitude 17.6° S), Brazil, Ho Chi Minh City, (HCM; 10.5° N, 106.3° E; dip latitude 2.9° N), Vietnam, Okinawa (OKI; 26.3° N, 127.8° E; dip latitude 21.2° N), Japan, are presented. Also, the GPS observations obtained at different stations in the equatorial and low-latitude regions in the Brazilian sector are presented. On the night of 24–25 August 2005, the h′F variations show traveling ionospheric disturbances associated with Joule heating in the auroral zone from SJC to PAL. The foF2 variations show a positive storm phase on the night of 24–25 August at PAL and SJC during the recovery phase. Also, the GPS-VTEC observations at several stations in the Brazilian sector show a fairly similar positive storm phase on 24 August. During the fast decrease of Dst (between 10:00 and 11:00 UT) on 24 August, there is a prompt penetration of electric field of magnetospheric origin that result in abrupt increase (∼12:00 UT) in foF2 at PAL, SJC (Brazil) and OKI (Japan) and in VTEC at IMPZ, BOMJ, PARA and SMAR (Brazil). OKI showed strong oscillations of the F-region on the night 24 August resulted to the propagation of traveling atmospheric disturbances (TADs) by Joule heating in the auroral region. These effects result a strong positive observed at OKI station. During the daytime on 25 August, in the recovery phase, the foF2 observations showed positive ionospheric storm at HCM station. Some differences in the latitudinal response of the F-region is also observed in the South American and East Asian sectors.     

Subjective vertical before and after space flight

Three scientist astronauts on the D1 spacelab mission participated in a series of orientation experiments before and after exposure to orbital weightlessness. Each subject was tilted about a roll axis at 15 deg intervals up to +/-90 deg. At each angle the subject set a luminous line to what he perceived to be the vertical. The results of these tests are presented.     

Theory of Operation of an Elastically Supported Tuned Gyroscope

Detailed derivation of the transfer function for a multigimbal, elastically supported, tuned gyro is presented and comparison made between its characteristics and those of a classical two-axis, free-rotor gyro. Knowledge of the gyro transfer function is necessary for the purpose of servo analysis of the system in which the gyro is used; also, the transfer function is a basis of evaluation of errors caused by angular inputs that occur at twice spin frequency.