A new perspective of carcinogenesis from protracted high-LET radiation arises from the two-stage clonal expansion model.

When applied to the Colorado Plateau miner population, the two-stage clonal expansion (TSCE) model of radiation carcinogenesis predicts that radiation-induced promotion dominates radiation-induced initiation. Thus, according to the model, at least for alpha-particle radiation from inhaled radon daughters, lung cancer induction over long periods of protracted irradiation appears to be dominated by radiation-induced modification of the proliferation kinetics of already-initiated cells rather than by direct radiation-induced initiation (i.e., mutation) of normal cells. We explore the possible consequences of this result for radiation exposures to space travelers on long missions. Still unknown is the LET dependence of this effect. Speculations of the cause of this phenomenon include the suggestion that modification of cell kinetics is caused by a "bystander" effect, i.e., the traversal of normal cells by alpha particles, followed by the signaling of these cells to nearby initiated cells which then modify their proliferation kinetics.     

Autogeneration of an Instability of a Plasma Composition Equilibrium in the Plasmaspheric Transition Region during a Postsunset High-Altitude Launch of the Vertikal'-10 Rocket

A cause of the instability of equilibrium of plasma ion composition is discussed and exemplified by the data on a burst of amplitudes of small-scale plasma irregularities in the plasmaspheric transition region during an evening launch of the Vertikal'-10 rocket. This burst is accompanied by a simultaneous decrease in the average plasma density at altitudes of 700–1100 km. Specific features of the observed events are compared to postsunset incoherent scatter radar observations of the ion diffusion flux density. It is demonstrated that the instability is caused by peculiarities of the protonosphere–ionosphere interaction associated with a sharp difference between thermal conditions of the ionospheric and protonospheric air shortly after sunset. The induced nonuniformity of postsunset cooling of the protonospheric–ionospheric plasma causes density irregularities in ion diffusion fluxes and generates local bunches of heavy ions, which are usually only a minor impurity to lighter ions. As a result, conditions are created that are favorable for the nondissipative accumulation of potential energy for the mutual opposition of two or more groups of ions with different masses and for the subsequent release of this energy by a threshold excitation of impurity-driven plasma instabilities.     

Families of Periodic Solutions to the Beletsky Equation

A review of achievements in the investigation of the planar periodic oscillations and rotations of a satellite around its center of mass, which moves along an elliptic orbit in the central gravitational field, is presented. These oscillations and rotations of the satellite are described by an ordinary differential equation (Beletsky equation) of the second order with periodic coefficients and two parameters. The equation is equivalent to a periodic Hamiltonian system with a single degree of freedom and has a singularity. It turned out that two-parameter families of the generalized periodic solutions to this simple equation form complicated structures of a new type. A comparison of numerous separate results made it possible to outline a sufficiently unified and complete picture of the location and structure of the families of generalized 2-periodic solutions with an integer number of rotation. These families are compared with known data related to the resonance rotations of the natural satellites in the solar system.     

Aspartic acid racemization and age-depth relationships for organic carbon in Siberian permafrost

We have analyzed the degree of racemization of aspartic acid in permafrost samples from Northern Siberia, an area from which microorganisms of apparent ages up to a few million years have previously been isolated and cultured. We find that the extent of aspartic acid racemization in permafrost cores increases very slowly up to an age of approximately 25,000 years (around 5 m in depth). The apparent temperature of racemization over the age range of 0-25,000 years, determined using measured aspartic acid racemization rate constants, is -19 degrees C. This apparent racemization temperature is significantly lower than the measured environmental temperature (-11 to -13 degrees C) and suggests active recycling of D-aspartic acid in Siberian permafrost up to an age of around 25,000 years. This indicates that permafrost organisms are capable of repairing some molecular damage incurred while in a "dormant" state over geologic time.     

A search for optical beacons: implications of null results

Over the past few years a series of searches for interstellar radio beacons have taken place using the Parkes radio telescope. Here we report hitherto unpublished results from a search for optical beacons from 60 solar-type stars using the Perth-Lowell telescope. We discuss the significance of the null results from these searches, all of which were based on the interstellar contact channel hypothesis. While the null results of all searches to date can be explained simply by the nonexistence of electromagnetically communicating life elsewhere in the Milky Way, four other possible explanations that do not preclude its existence are proposed: (1) Extraterrestrial civilizations desiring to make contact through the use of electromagnetic beacons have a very low density in the Milky Way. (2) The interstellar contact channel hypothesis is incorrect, and beacons exist at frequencies that have not yet been searched. (3) The search has been incomplete in terms of sensitivity and/or target directions: Beacons exist, but more sensitive equipment and/or more searching is needed to achieve success. (4) The search has occurred before beacon signals can be expected to have arrived at the Earth, and beacon signals may be expected in the future. Based on consideration of the technology required for extraterrestrial civilizations to identify target planets, we argue that the fourth possibility is likely to be valid and that powerful, easily detectable beacons could be received in coming centuries.     

Eye light flashes on the Mir space station

The phenomenon of light flashes (LF) in eyes for people in space has been investigated onboard Mir. Data on particles hitting the eye have been collected with the SilEye detectors, and correlated with human observations. It is found that a nucleus in the radiation environment of Mir has roughly a 1% probability to cause an LF, whereas the proton probability is almost three orders of magnitude less. As a function of LET, the LF probability increases above 10 keV/micrometer, reaching about 5% at around 50 keV/micrometer.     

Long-term operation of "Orlan" space suits in the "Mir" orbiting station: experience obtained and its application

The started assembly of the International Space Station (ISS) and its further operation will call for a great number of extravehicular activity sorties (EVA) to be performed by ISS crews. Therefore, of great importance is to make use of the EVA experience gained by cosmonauts in the process of 15-year operation of the Mir orbiting station (OS). Over the 15-year period, Mir crewmembers wearing Orlan type semi-rigid space suits have accumulated 158 man/sorties from the orbiting station. Crewmembers used 15 suits in orbit and some of the suits were in operation for more than 3 years. The paper presents principal design features, which provide effective and safe operation of orbit-based suits, and briefly describes procedures for preparation and maintenance of suit systems, which ensure long-term operation of space suit in orbit. The paper gives results of the space suit modifications, presents suit performance characteristics and lists novel or upgraded components of the space suit and its systems. The paper also summarizes improvements in the Orlan type suits described in some earlier publications. They refer, in the first run, to the improvement of space suit operations characteristics and reliability, and the utilization of the Orlan type space suit in the ISS program. The paper analyses the experience gained and drawbacks detected and observations made, and gives statistical data on long-term space suit operations aboard the Mir station. The paper reviews certain problems in the process of EVAs performed from the station, and describes the ways of their solution as applied to the further utilization of the suit within the ISS program.     

Beam-Park-Experiment-1/2000 with TIRA

A monostatic 24-h debris observation campaign (BPE-1/2000) has been prepared and conducted using FGAN's TIRA L-Band system. Based on experiences from previous Beam-park experiments a similar largely automated data processing is applied on an extended range window of 300–2000km. More than 1500 detections are encountered, 471 of them are verified as being real objects in Low-Earth-Orbit (LEO). PROOF's observation forecasting of catalogued objects is evaluated against the observed objects, and the difficulties obtaining radar cross-sections (RCSs) and object sizes from Beam-park experiments are discussed. Sidelobe detections are identified by using background information like two-line element (TLE) sets and/or catalogued RCSs.In comparison with previous experiments, the statistics show similarities confirming the concept of Beam-park experiments for space debris observations, despite the snapshot character of 24-h experiments. The comparison with MASTER/PROOF'99 and ORDEM2000 leads to a reasonable agreement between models and observations.     

Study of cosmic rays and light flashes on board Space Station MIR: the SilEye experiment.

The SilEye experiment aims to study the cause and processes related to the anomalous Light Flashes (LF) perceived by astronauts in orbit and their relation with Cosmic Rays. These observations will be also useful in the study of the long duration manned space flight environment. Two PC-driven silicon detector telescopes have been built and placed aboard Space Station MIR. SilEye-1 was launched in 1995 and provided particles track and LF information; the data gathered indicate a linear dependence of FLF(Hz) ( 4 2) 10(3) 5.3 1.7 10(4) Fpart(Hz) if South Atlantic Anomaly fluxes are not included. Even though higher statistic is required, this is an indication that heavy ion interactions with the eye are the main LF cause. To improve quality and quantity of measurements, a second apparatus, SilEye-2, was placed on MIR in 1997, and started work from August 1998. This instrument provides energetic information, which allows nuclear identification in selected energy ranges; we present preliminary measurements of the radiation field inside MIR performed with SilEye-2 detector in June 1998.