Study of water-salt metabolism and renal function in cosmonauts

In manned space flights the renal function and water-salt metabolism undergo substantial changes. With the reserve capabilities of kidneys in mind, their function and regulation of the water-salt balance were investigated in cosmonauts postflight and in Earth-bound simulation experiments with the aid of water loading, hormonal injections (pituitrin, engiotensin, DOCA, ACTH); water- and ion-release were also studied during LBNP and physical exercises. The cosmonauts who performed space flights of 2 to 5 days showed water retention and increased urine excretion of salts during the first postflight days in response to a water load. After the 18-day flight water excretion remained unchanged whereas salt excretion increased. The capacity for osmotic concentration and urine dilution did not alter. The study of the hormonal effect in simulation experiments of different duration demonstrated a normal renal response to the hormonal excretion. After the LBNP tests and physical exercises the water- and salt-excretion declined; a correlation between the level of water- and salt-excretion and the level of these loads was established. The data on the blood- and urine-ionic composition, excretion of nitrogen metabolites, and hormones postflight as well as the results of load and functional tests suggest that changes in the renal function of cosmonauts in weightlessness are associated with regulatory effects on the kidney rather than disturbances in the function of nephron cells.     

Summary of medical investigations in the U.S.S.R. manned space missions.

The results of biomedical investigations carried out in the U.S.S.R. manned space missions are discussed. Their basic result is well-documented evidence that man can perform space flights of long duration. The investigations have demonstrated no direct correlation between inflight or postflight physiological reactions of crewmembers and flight duration. In all likelihood, this can be attributed to the fact that special exercises done inflight efficiently prevented adverse effects of weightlessness. However, human reactions to weightlessness need further study. They include negative calcium balance and anemia as well as vestibulo-autonomic disorders shown by crewmembers at early stages of weightlessness. Attention should be given to psychological, social-psychological and ethical problems that may also limit further increase in flight duration.     

Motion of a Planet with a Complex Structure

The motion of a planet consisting of a mantle and a core (solid bodies) connected by a viscoelastic layer and interacting with each other and an external point mass by the law of gravitation is considered. The mutual motions of the core and mantle are investigated assuming that the centers of mass of the planet and external point mass moves along undisturbed Keplerian orbits around the common center of mass of the system. The planetary core and mantle have an axial symmetry and different principal moments of inertia, which leads to a displacement of the center of mantle relative to the center of core and to their mutual rotations. The results obtained on the basis of averaged equations are illustrated by the example of the Earth–Moon system.     

Some technical aspects of gaseous detonation

This paper briefly describes two attempts to utilize detonative combustion processes to MHD conversion of thermal energy of fuel to electrical energy and bonding of atmospheric nitrogen. For this purpose a continuous impulse detonation chamber with a frequency up to 200 cps was constructed. Using methane-oxygen-nitrogen mixtures the chamber was maintained in stable operation for several hundred hours. Oil was also employed as fuel.Estimates based on experimental data showed that up to 2% of chemical energy of the fuel may be converted into electrical energy. The use of an accelerating nozzle may improve this result.The concentration of nitrogen oxide in combustion products of the detonation wave was higher by 14% than that expected under usual combustion conditions.The advantages of this type of apparatus are: absence of compressors for fuel and oxidant, impulse current generation, low temperatures of chamber walls, and operation over a large range of operating conditions.Problems associated with the effect of the magnetic field on the propagation of the detonation wave are discussed and the possibility of applying the Zeldovich theory to the case of MHD interaction is described. It is shown that the detonation velocity may either increase or decrease depending on the relative orientation of the direction of magnetic field with respect to the detonation wave.     

Solving Optimization Problems for the Flight Trajectories of a Spacecraft with a High-Thrust Jet Engine in Pulse Formulation for an Arbitrary Gravitational Field in a Vacuum

A mathematically well-posed technique is suggested to obtain first-order necessary conditions of local optimality for the problems of optimization to be solved in a pulse formulation for flight trajectories of a spacecraft with a high-thrust jet engine (HTJE) in an arbitrary gravitational field in vacuum. The technique is based on the Lagrange principle of derestriction for conditional extremum problems in a function space. It allows one to formalize an algorithm of change from the problems of optimization to a boundary-value problem for a system of ordinary differential equations in the case of any optimization problem for which the pulse formulation makes sense. In this work, such a change is made for the case of optimizing the flight trajectories of a spacecraft with a HTJE when terminal and intermediate conditions (like equalities, inequalities, and the terminal functional of minimization) are taken in a general form. As an example of the application of the suggested technique, we consider in this work, within the framework of a bounded circular three-point problem in pulse formulation, the problem of constructing the flight trajectories of a spacecraft with a HTJE through one or several libration points (including the case of going through all libration points) of the Earth–Moon system. The spacecraft is launched from a circular orbit of an Earth's artificial satellite and, upon passing through a point (or points) of libration, returns to the initial orbit. The expenditure of mass (characteristic velocity) is minimized at a restricted time of transfer.     

Space education: a step forward

One hundred European university students, with different interests and backgrounds, were asked to complete a questionnaire aimed at understanding their general knowledge and personal rapport with space issues and activities. Although the overall interest in space seemed to be relatively satisfactory, the data resulting from the survey—used for statistical purposes only—showed a poor awareness concerning the past, present and future of space programmes and achievements, and more generally of the economic, political and social implications of space. Stimulated and moved by the survey questions, the students interviewed showed their worries about the already developing process of division, control and commercialisation of space, underlining how the concept of education is differentiated from that of information when dealing with these issues. However, at the same time, all their statements seemed to be based on simple assumptions, preconceptions and presumptions. On the basis of the survey results, the final section of the paper reviews and discusses the present situation of space education in Europe, analysing its deficiencies and suggesting modifications, adjustments and a “step forward” that should be taken into consideration.     

Translational–Rotational Motion of a Viscoelastic Sphere in Gravitational Field of an Attracting Center and a Satellite

We study the translational–rotational motion of a planet modeled by a viscoelastic sphere in the gravitational fields of an immovable attracting center and a satellite modeled as material points. The satellite and the planet move with respect to their common center of mass that, in turn, moves with respect to the attracting center. The exact system of equations of motion of the considered mechanical system is deduced from the D'Alembert–Lagrange variational principle. The method of separation of motions is applied to the obtained system of equations and an approximate system of ordinary differential equations is deduced which describes the translational–rotational motion of the planet and its satellite, taking into account the perturbations caused by elasticity and dissipation. An analysis of the deformed state of the viscoelastic planet under the action of gravitational forces and forces of inertia is carried out. It is demonstrated that in the steady-state motion, when energy dissipation vanishes, the planet's center of mass and the satellite move along circular orbits with respect to the attracting center, being located on a single line with it. The viscoelastic planet in its steady-state motion is immovable in the orbital frame of reference. It is demonstrated that this steady-state motion is unstable.     

Regulation of autonomic nervous system in space and magnetic storms.

Variations in the earth's magnetic field and magnetic storms are known to be a risk factor for the development of cardiovascular disorders. The main "targets" for geomagnetic perturbations are the central nervous system and the neural regulation of vascular tone and heart rate variability. This paper presents the data about effect of geomagnetic fluctuations on human body in space. As a method for research the analysis of heart rate variability was used, which allows evaluating the state of the sympathetic and parasympathetic parts of the autonomic nervous system, vasomotor center and subcortical neural centers activity. Heart rate variability data were analyzed for 30 cosmonauts at the 2nd day of space flight on transport spaceship Soyuz (32nd orbit). There were formed three groups of cosmonauts: without magnetic storm (n=9), on a day with magnetic storm (n=12) and 1-2 days after magnetic storm (n=9). The present study was the first to demonstrate a specific impact of geomagnetic perturbations on the system of autonomic circulatory control in cosmonauts during space flight. The increasing of highest nervous centers activity was shown for group with magnetic storms, which was more significant on 1-2 days after magnetic storm. The use of discriminate analysis allowed to classify indicated three groups with 88% precision. Canonical variables are suggested to be used as criterions for evaluation of specific and non-specific components of cardiovascular reactions to geomagnetic perturbations. The applied aspect of the findings from the present study should be emphasized. They show, in particular, the need to supplement the medical monitoring of cosmonauts with predictions of probable geomagnetic perturbations in view of the prevention of unfavorable states appearances if the adverse reactions to geomagnetic perturbations are added to the tension experienced by regulatory systems during various stresses situations (such as work in the open space).     

The influence of gravity on the process of development of animal systems

The development of animal systems is described in terms of a series of overlapping phases: pattern specification; differentiation; growth; and aging. The extent to which altered (micro) gravity (g) affects those phases is briefly reviewed for several animal systems. As a model, amphibian egg/early embryo is described. Recent data derived from clinostat protocols indicates that microgravity simulation alters early pattern specification (dorsal/ventral polarity) but does not adversely influence subsequent morphogenesis. Possible explanations for the absence of catastrophic microgravity effects on amphibian embryogenesis are discussed.