Biological responses to space: results of the experiment "Exobiological Unit" of ERA on EURECA I.

Spores of different strains of Bacillus subtilis and the Escherichia coli plasmid pUC19 were exposed to selected conditions of space (space vacuum and/or defined wavebands and intensities of solar ultraviolet radiation) in the experiment ER 161 "Exobiological Unit" of the Exobiology Radiation Assembly (ERA) on board of the European Retrievable Carrier (EURECA). After the approximately 11 months lasting mission, their responses were studied in terms of survival, mutagenesis in the his (B. subtilis) or lac locus (pUC19), induction of DNA strand breaks, efficiency of DNA repair systems, and the role of external protective agents. The data were compared with those of a simultaneously running ground control experiment. The survival of spores treated with the vacuum of space, however shielded against solar radiation, is substantially increased, if they are exposed in multilayers and/or in the presence of glucose as protective, whereas all spores in "artificial meteorites", i.e. embedded in clays or simulated Martian soil, are killed. Vacuum treatment leads to an increase of mutation frequency in spores, but not in plasmid DNA. Extraterrestrial solar ultraviolet radiation is mutagenic, induces strand breaks in the DNA and reduces survival substantially; however, even at the highest fluences, i.e. 3 x 10(8) J m-2, a small but significant fraction of spores survives the insolation. Action spectroscopy confirms results of previous space experiments of a synergistic action of space vacuum and solar UV radiation with DNA being the critical target.     

Influence of graviceptives cues at different level of visual information processing: the effect of prolonged weightlessness

We evaluated the influence of prolonged weightlessness on the performance of visual tasks in the course of the Russian-French missions ANTARES, Post-ANTARES and ALTAIR aboard the MIR station. Eight cosmonauts were subjects in two experiments executed pre-flight, in-flight and post-flight sessions.

In the first experiment, cosmonauts performed a task of symmetry detection in 2-D polygons. The results indicate that this detection is locked in a head retinal reference frame rather than in an environmentally defined one as meridional orientations of symmetry axis (vertical and horizontal) elicited faster response times than oblique ones. However, in weightlessness the saliency of a retinally vertical axis of symmetry is no longer significantly different from an horizontal axis. In the second experiment, cosmonauts performed a mental rotation task in which they judged whether two 3-D objects presented in different orientations were identical. Performance on this task is basically identical in weightlessness and normal gravity.     

The effect of head-down tilt on brain potentials related to visual attention

To study the possible effect of simulated weightlessness on brain function state, the brain event-related potentials (ERPs) in a simple visual selective response task were compared between HDT and HUT in 9 normal subjects. The results were: The Target(T) and non-Target(NT) flash signals both induced significant slow positive potentials which were supposed to related to the attention state; the amplitude of the positive potentials in frontal regions decreased significantly especially for NT-ERPs during HDT comprared with that during HUT. The data reported provide new evidence indicating that more attention should be paid on the brain function study during space flight.     

Effect of potassium and calcium loading on healthy subjects under hypokinesia and physical exercise with fluid and salt supplements

The objective of this investigation was to determine the acute responses to the electrolyte challenges under hypokinesia and physical exercise (PE) of different intensities with fluid and salt supplementation (FSS). The studies were performed on 12 physically healthy male volunteers aged 19-24 years under 364 days of hypokinesia (decreased number of steps per day) with a set of PE with FSS. The volunteers were divided into two equal groups. The first group was subjected to a set of intensive PE and the second group was submitted to a set of moderate PE. Both groups of subjects consumed daily water and salt supplements that aimed to increase the body hydration level. For simulation of the hypokinetic effect all subjects were kept under an average of 3000 steps per day. Functional tests with a potassium chloride (KCl) and calcium lactate (Cal) load were performed during the hypokinetic period of 364 days and the 60-day, prehypokinetic period that served as control, while both groups of subjects consumed daily calcium and potassium supplements. The concentration of electrolyte and hormone levels in the blood and their excretion rate in urine were determined. Renal excretion of calcium and potassium and the blood concentration thereof increased markedly in both groups of subjects. With the potassium chloride load tests the increased potassium excretion was accompanied by higher aldosterone and insulin blood levels, and with the calcium lactate load tests the increased calcium excretion was accompanied by a decreased parathyroid content in the blood. FSS and PE, regardless of intensity, failed to attenuate calcium and potassium losses. Additional intake of KCl and Cal also failed to normalize potassium and calcium abnormalities. It was concluded that during the KCl and Cal loading tests, the increased losses of potassium and calcium in the hypokinetic subjects were due to the inability of their bodies to retain these electrolytes, and that electrolyte abnormalities could not be reversed by PE or rehydration in individuals subjected to prolonged restriction of motor activity.     

Analysis of Multimodal Systems

The estimation of a multimodal linear system whose mode-to-mode transitions are described by a finite-state Markov chain is described. The problem has application in studying separation standards in an air traffic control environment. An optimal solution is formulated which is computationally infeasible. A suboptimal estimator is then derived which closely approximates the optimal estimator. An example is presented to illustrate the technique.     

Interference between FM Carriers and a Digitally Modulated SCPC Circuit

The interference from the digital single channel per carrier (SCPC) circuits into frequency-modulated carrier systems has been calculated by convolving the desired and the interfering spectra extending the previously published works. Resulting interference noise power in FDM/FM systems covering a wide range of modulation indices and basebands has been presnted. Also plots of interference noise power as a function of the number of SCPC circuits have been presented for various values of carrier power to interference power ratios.     

Medium PRF set selection using evolutionary algorithms

This paper presents a new and novel method of selecting multiple pulse repetition frequency (PRF) sets for use in medium PRF pulsed-Doppler radars. Evolutionary algorithms are used to minimise the blind areas in the range/Doppler space. The evolutionary algorithm allows optimal solutions to be generated quickly, far faster than with exhaustive searches, and is fully automatic, unlike existing techniques. The evolved solutions compare very favorably against the results of both an exhaustive search and existing published PRF set selection methods. This evolutionary approach to generation of PRF sets is a major advance in medium PRF radar design.     

A new and robust CFAR detection algorithm

A constant false alarm rate (CFAR) detection method which is based on a combination of median and morphological filters (MEMO) is proposed. The MEMO algorithm has robust performance with small CFAR loss, very good behavior at clutter edges and high detection performance in the case of closely spaced narrowband signals (targets). The proposed MEMO method is favourably compared with cell averaging (CA) and ordered statistics (OS) CFAR detectors. The Monte Carlo method is employed to analyze the MEMO-CFAR detector     

Magnetosphere Imaging Instrument (MIMI) on the Cassini Mission to Saturn/Titan

The magnetospheric imaging instrument (MIMI) is a neutral and charged particle detection system on the Cassini orbiter spacecraft designed to perform both global imaging and in-situ measurements to study the overall configuration and dynamics of Saturn’s magnetosphere and its interactions with the solar wind, Saturn’s atmosphere, Titan, and the icy satellites. The processes responsible for Saturn’s aurora will be investigated; a search will be performed for substorms at Saturn; and the origins of magnetospheric hot plasmas will be determined. Further, the Jovian magnetosphere and Io torus will be imaged during Jupiter flyby. The investigative approach is twofold. (1) Perform remote sensing of the magnetospheric energetic (E > 7 keV) ion plasmas by detecting and imaging charge-exchange neutrals, created when magnetospheric ions capture electrons from ambient neutral gas. Such escaping neutrals were detected by the Voyager l spacecraft outside Saturn’s magnetosphere and can be used like photons to form images of the emitting regions, as has been demonstrated at Earth. (2) Determine through in-situ measurements the 3-D particle distribution functions including ion composition and charge states (E > 3 keV/e). The combination of in-situ measurements with global images, together with analysis and interpretation techniques that include direct “forward modeling’’ and deconvolution by tomography, is expected to yield a global assessment of magnetospheric structure and dynamics, including (a) magnetospheric ring currents and hot plasma populations, (b) magnetic field distortions, (c) electric field configuration, (d) particle injection boundaries associated with magnetic storms and substorms, and (e) the connection of the magnetosphere to ionospheric altitudes. Titan and its torus will stand out in energetic neutral images throughout the Cassini orbit, and thus serve as a continuous remote probe of ion flux variations near 20R _S (e.g., magnetopause crossings and substorm plasma injections). The Titan exosphere and its cometary interaction with magnetospheric plasmas will be imaged in detail on each flyby. The three principal sensors of MIMI consists of an ion and neutral camera (INCA), a charge–energy–mass-spectrometer (CHEMS) essentially identical to our instrument flown on the ISTP/Geotail spacecraft, and the low energy magnetospheric measurements system (LEMMS), an advanced design of one of our sensors flown on the Galileo spacecraft. The INCA head is a large geometry factor (G ∼ 2.4 cm² sr) foil time-of-flight (TOF) camera that separately registers the incident direction of either energetic neutral atoms (ENA) or ion species (≥5^∘ full width half maximum) over the range 7 keV/nuc < E < 3 MeV/nuc. CHEMS uses electrostatic deflection, TOF, and energy measurement to determine ion energy, charge state, mass, and 3-D anisotropy in the range 3 ≤ E ≤ 220 keV/e with good (∼0.05 cm² sr) sensitivity. LEMMS is a two-ended telescope that measures ions in the range 0.03 ≤ E ≤ 18 MeV and electrons 0.015 ≤ E≤ 0.884 MeV in the forward direction (G ∼ 0.02 cm² sr), while high energy electrons (0.1–5 MeV) and ions (1.6–160 MeV) are measured from the back direction (G ∼ 0.4 cm² sr). The latter are relevant to inner magnetosphere studies of diffusion processes and satellite microsignatures as well as cosmic ray albedo neutron decay (CRAND). Our analyses of Voyager energetic neutral particle and Lyman-α measurements show that INCA will provide statistically significant global magnetospheric images from a distance of ∼60 R _S every 2–3 h (every ∼10 min from ∼20 R _S). Moreover, during Titan flybys, INCA will provide images of the interaction of the Titan exosphere with the Saturn magnetosphere every 1.5 min. Time resolution for charged particle measurements can be < 0.1 s, which is more than adequate for microsignature studies. Data obtained during Venus-2 flyby and Earth swingby in June and August 1999, respectively, and Jupiter flyby in December 2000 to January 2001 show that the instrument is performing well, has made important and heretofore unobtainable measurements in interplanetary space at Jupiter, and will likely obtain high-quality data throughout each orbit of the Cassini mission at Saturn. Sample data from each of the three sensors during the August 18 Earth swingby are shown, including the first ENA image of part of the ring current obtained by an instrument specifically designed for this purpose. Similarily, measurements in cis-Jovian space include the first detailed charge state determination of Iogenic ions and several ENA images of that planet’s magnetosphere.This revised version was published online in July 2005 with a corrected cover date.     

Comparison of ≳40 keV Electron Events at High and Low Heliolatitudes: Ulysses/HI-SCALE and ACE/EPAM

We have performed a joint survey of anisotropic ≳40 keV electron events from August 1997 to September 2000 using the matched detectors on the Ulysses (ULS)/HI-SCALE and the ACE/EPAM instruments. A computer algorithm selected events with strong, statistically significant pitch-angle anisotropies. Electron pitch-angle distributions at ACE (∼1 AU) are often ‘beams’ that are strongly collimated along the local interplanetary magnetic field (IMF). These flare-associated impulsive injections can display rapid rise times (∼15 min) and slower decays, or more irregular intensity histories. At ULS, the electron intensities are lower and the time histories smoother, but strong anisotropies are still observable, indicating direct, nearly field-aligned propagation outward from the Sun. We focus on four event periods, selected from the survey, during times when the angle between the footpoints of the IMF lines intersecting ACE and ULS is small. These events span three full years and cover a wide range of distances and heliographic latitudes. We found one reasonably good association between impulsive electron events at ACE and ULS, and two events with small field-aligned gradients. This revised version was published online in August 2006 with corrections to the Cover Date.